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Patent code US9777010

Compile Data Set for Download or QSAR
Found 124 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249469
PNG
(US10072016, Compound 68 | US9434727, 68 | US977701...)
Show SMILES COC(=O)N1CCc2[nH]nc(C(=O)N3CCC(CC3)c3cccc(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C21H22F4N4O3/c1-32-20(31)29-10-7-16-14(11-29)18(27-26-16)19(30)28-8-5-12(6-9-28)13-3-2-4-15(22)17(13)21(23,24)25/h2-4,12H,5-11H2,1H3,(H,26,27)
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n/an/a<1.37n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249550
PNG
(US10072016, Compound 148 | US9434727, 148 | US9777...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(CCc23)C#N)c1Cl
Show InChI InChI=1S/C19H19ClFN5O/c20-17-13(2-1-3-15(17)21)12-4-8-26(9-5-12)19(27)18-14-6-7-25(11-22)10-16(14)23-24-18/h1-3,12H,4-10H2,(H,23,24)
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n/an/a<1.37n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249485
PNG
(US10072016, Compound 83 | US9434727, 83 | US977701...)
Show SMILES CC(=O)N1Cc2[nH]nc(C(=O)N3CCC(CC3)c3ccc(F)c(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C20H19F5N4O2/c1-10(30)29-8-13-15(9-29)26-27-18(13)19(31)28-6-4-11(5-7-28)12-2-3-14(21)17(22)16(12)20(23,24)25/h2-3,11H,4-9H2,1H3,(H,26,27)
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n/an/a<1.37n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249474
PNG
(US10072016, Compound 77 | US9434727, 73 | US943472...)
Show SMILES COCCN1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1cccc(F)c1C(F)(F)F
Show InChI InChI=1S/C22H26F4N4O2/c1-32-12-11-29-8-7-16-18(13-29)27-28-20(16)21(31)30-9-5-14(6-10-30)15-3-2-4-17(23)19(15)22(24,25)26/h2-4,14H,5-13H2,1H3,(H,27,28)
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n/an/a 2.88n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249554
PNG
(US10072016, Compound 152 | US9434727, 152 | US9777...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2nnc3ccc(cn23)C#N)c1Cl
Show InChI InChI=1S/C19H15ClFN5O/c20-17-14(2-1-3-15(17)21)13-6-8-25(9-7-13)19(27)18-24-23-16-5-4-12(10-22)11-26(16)18/h1-5,11,13H,6-9H2
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n/an/a 3.10n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249522
PNG
(US10072016, Compound 120 | US9434727, 120 | US9777...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(CCc23)C#N)c(c1F)C(F)(F)F
Show InChI InChI=1S/C20H18F5N5O/c21-14-2-1-12(16(17(14)22)20(23,24)25)11-3-7-30(8-4-11)19(31)18-13-5-6-29(10-26)9-15(13)27-28-18/h1-2,11H,3-9H2,(H,27,28)
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n/an/a 3.45n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249466
PNG
(US10072016, Compound 65 | US9434727, 65 | US977701...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2nnc3ccc(cn23)C#N)c1C(F)(F)F
Show InChI InChI=1S/C20H15F4N5O/c21-15-3-1-2-14(17(15)20(22,23)24)13-6-8-28(9-7-13)19(30)18-27-26-16-5-4-12(10-25)11-29(16)18/h1-5,11,13H,6-9H2
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n/an/a 4.13n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249482
PNG
(US10072016, Compound 81 | US9434727, 80 | US943472...)
Show SMILES CC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1ccc(F)c(F)c1C(F)(F)F
Show InChI InChI=1S/C21H21F5N4O2/c1-11(31)30-9-6-14-16(10-30)27-28-19(14)20(32)29-7-4-12(5-8-29)13-2-3-15(22)18(23)17(13)21(24,25)26/h2-3,12H,4-10H2,1H3,(H,27,28)
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n/an/a 4.33n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249482
PNG
(US10072016, Compound 81 | US9434727, 80 | US943472...)
Show SMILES CC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1ccc(F)c(F)c1C(F)(F)F
Show InChI InChI=1S/C21H21F5N4O2/c1-11(31)30-9-6-14-16(10-30)27-28-19(14)20(32)29-7-4-12(5-8-29)13-2-3-15(22)18(23)17(13)21(24,25)26/h2-3,12H,4-10H2,1H3,(H,27,28)
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n/an/a 4.33n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249482
PNG
(US10072016, Compound 81 | US9434727, 80 | US943472...)
Show SMILES CC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1ccc(F)c(F)c1C(F)(F)F
Show InChI InChI=1S/C21H21F5N4O2/c1-11(31)30-9-6-14-16(10-30)27-28-19(14)20(32)29-7-4-12(5-8-29)13-2-3-15(22)18(23)17(13)21(24,25)26/h2-3,12H,4-10H2,1H3,(H,27,28)
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n/an/a 4.33n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249481
PNG
(US10072016, Compound 79 | US9434727, 79 | US977701...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(CC4CC4)CCc23)c1C(F)(F)F
Show InChI InChI=1S/C23H26F4N4O/c24-18-3-1-2-16(20(18)23(25,26)27)15-6-10-31(11-7-15)22(32)21-17-8-9-30(12-14-4-5-14)13-19(17)28-29-21/h1-3,14-15H,4-13H2,(H,28,29)
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n/an/a 4.35n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249464
PNG
(US10072016, Compound 63 | US9434727, 63 | US977701...)
Show SMILES CC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1cccc(F)c1C(F)(F)F
Show InChI InChI=1S/C21H22F4N4O2/c1-12(30)29-10-7-15-17(11-29)26-27-19(15)20(31)28-8-5-13(6-9-28)14-3-2-4-16(22)18(14)21(23,24)25/h2-4,13H,5-11H2,1H3,(H,26,27)
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n/an/a 4.46n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249564
PNG
(US10072016, Compound 162 | US9434727, 162 | US9777...)
Show SMILES FC(F)(F)c1c(Cl)cccc1C1CCN(CC1)C(=O)c1nnc2ccc(cn12)C#N
Show InChI InChI=1S/C20H15ClF3N5O/c21-15-3-1-2-14(17(15)20(22,23)24)13-6-8-28(9-7-13)19(30)18-27-26-16-5-4-12(10-25)11-29(16)18/h1-5,11,13H,6-9H2
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n/an/a 4.82n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249552
PNG
(US10072016, Compound 150 | US9434727, 150 | US9777...)
Show SMILES CC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1cccc(F)c1Cl
Show InChI InChI=1S/C20H22ClFN4O2/c1-12(27)26-10-7-15-17(11-26)23-24-19(15)20(28)25-8-5-13(6-9-25)14-3-2-4-16(22)18(14)21/h2-4,13H,5-11H2,1H3,(H,23,24)
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n/an/a 4.84n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249544
PNG
(US10072016, Compound 142 | US9434727, 142 | US9777...)
Show SMILES Fc1ccc(c(c1)C1CCN(CC1)C(=O)c1nnc2ccc(cn12)C#N)C(F)(F)F
Show InChI InChI=1S/C20H15F4N5O/c21-14-2-3-16(20(22,23)24)15(9-14)13-5-7-28(8-6-13)19(30)18-27-26-17-4-1-12(10-25)11-29(17)18/h1-4,9,11,13H,5-8H2
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n/an/a 4.88n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249550
PNG
(US10072016, Compound 148 | US9434727, 148 | US9777...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(CCc23)C#N)c1Cl
Show InChI InChI=1S/C19H19ClFN5O/c20-17-13(2-1-3-15(17)21)12-4-8-26(9-5-12)19(27)18-14-6-7-25(11-22)10-16(14)23-24-18/h1-3,12H,4-10H2,(H,23,24)
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n/an/a 5.12n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249543
PNG
(US10072016, Compound 141 | US9434727, 141 | US9777...)
Show SMILES CS(=O)(=O)N1CCc2[nH]nc(C(=O)N3CCC(CC3)c3cc(F)ccc3C(F)(F)F)c2C1
Show InChI InChI=1S/C20H22F4N4O3S/c1-32(30,31)28-9-6-17-15(11-28)18(26-25-17)19(29)27-7-4-12(5-8-27)14-10-13(21)2-3-16(14)20(22,23)24/h2-3,10,12H,4-9,11H2,1H3,(H,25,26)
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n/an/a 5.24n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249465
PNG
(US10072016, Compound 64 | US9434727, 64 | US977701...)
Show SMILES CS(=O)(=O)N1CCc2[nH]nc(C(=O)N3CCC(CC3)c3cccc(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C20H22F4N4O3S/c1-32(30,31)28-10-7-16-14(11-28)18(26-25-16)19(29)27-8-5-12(6-9-27)13-3-2-4-15(21)17(13)20(22,23)24/h2-4,12H,5-11H2,1H3,(H,25,26)
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n/an/a 5.36n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249466
PNG
(US10072016, Compound 65 | US9434727, 65 | US977701...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2nnc3ccc(cn23)C#N)c1C(F)(F)F
Show InChI InChI=1S/C20H15F4N5O/c21-15-3-1-2-14(17(15)20(22,23)24)13-6-8-28(9-7-13)19(30)18-27-26-16-5-4-12(10-25)11-29(16)18/h1-5,11,13H,6-9H2
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n/an/a 5.36n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249466
PNG
(US10072016, Compound 65 | US9434727, 65 | US977701...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2nnc3ccc(cn23)C#N)c1C(F)(F)F
Show InChI InChI=1S/C20H15F4N5O/c21-15-3-1-2-14(17(15)20(22,23)24)13-6-8-28(9-7-13)19(30)18-27-26-16-5-4-12(10-25)11-29(16)18/h1-5,11,13H,6-9H2
PDB
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n/an/a 5.36n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249466
PNG
(US10072016, Compound 65 | US9434727, 65 | US977701...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2nnc3ccc(cn23)C#N)c1C(F)(F)F
Show InChI InChI=1S/C20H15F4N5O/c21-15-3-1-2-14(17(15)20(22,23)24)13-6-8-28(9-7-13)19(30)18-27-26-16-5-4-12(10-25)11-29(16)18/h1-5,11,13H,6-9H2
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249519
PNG
(US10072016, Compound 117 | US9434727, 117 | US9777...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(CCc23)C2COC2)c(c1F)C(F)(F)F
Show InChI InChI=1S/C22H23F5N4O2/c23-16-2-1-14(18(19(16)24)22(25,26)27)12-3-6-30(7-4-12)21(32)20-15-5-8-31(13-10-33-11-13)9-17(15)28-29-20/h1-2,12-13H,3-11H2,(H,28,29)
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n/an/a 5.48n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249563
PNG
(US10072016, Compound 161 | US9434727, 161 | US9777...)
Show SMILES FC(F)(F)c1ccc(Cl)cc1C1CCN(CC1)C(=O)c1nnc2ccc(cn12)C#N
Show InChI InChI=1S/C20H15ClF3N5O/c21-14-2-3-16(20(22,23)24)15(9-14)13-5-7-28(8-6-13)19(30)18-27-26-17-4-1-12(10-25)11-29(17)18/h1-4,9,11,13H,5-8H2
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249559
PNG
(US10072016, Compound 157 | US9434727, 157 | US9777...)
Show SMILES Fc1cccc(c1C1CCN(CC1)C(=O)c1nnc2ccc(cn12)C#N)C(F)(F)F
Show InChI InChI=1S/C20H15F4N5O/c21-15-3-1-2-14(20(22,23)24)17(15)13-6-8-28(9-7-13)19(30)18-27-26-16-5-4-12(10-25)11-29(16)18/h1-5,11,13H,6-9H2
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249551
PNG
(US10072016, Compound 149 | US9434727, 149 | US9777...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(CCc23)C2COC2)c1Cl
Show InChI InChI=1S/C21H24ClFN4O2/c22-19-15(2-1-3-17(19)23)13-4-7-26(8-5-13)21(28)20-16-6-9-27(14-11-29-12-14)10-18(16)24-25-20/h1-3,13-14H,4-12H2,(H,24,25)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249482
PNG
(US10072016, Compound 81 | US9434727, 80 | US943472...)
Show SMILES CC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1ccc(F)c(F)c1C(F)(F)F
Show InChI InChI=1S/C21H21F5N4O2/c1-11(31)30-9-6-14-16(10-30)27-28-19(14)20(32)29-7-4-12(5-8-29)13-2-3-15(22)18(23)17(13)21(24,25)26/h2-3,12H,4-10H2,1H3,(H,27,28)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249546
PNG
(US10072016, Compound 144 | US9434727, 144 | US9777...)
Show SMILES CS(=O)(=O)N1CCc2[nH]nc(C(=O)N3CCC(CC3)c3cc(F)ccc3Cl)c2C1
Show InChI InChI=1S/C19H22ClFN4O3S/c1-29(27,28)25-9-6-17-15(11-25)18(23-22-17)19(26)24-7-4-12(5-8-24)14-10-13(21)2-3-16(14)20/h2-3,10,12H,4-9,11H2,1H3,(H,22,23)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249533
PNG
(US10072016, Compound 131 | US9434727, 131 | US9777...)
Show SMILES CC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1cc(F)cc(F)c1C(F)(F)F
Show InChI InChI=1S/C21H21F5N4O2/c1-11(31)30-7-4-14-17(10-30)27-28-19(14)20(32)29-5-2-12(3-6-29)15-8-13(22)9-16(23)18(15)21(24,25)26/h8-9,12H,2-7,10H2,1H3,(H,27,28)
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n/an/a 6.36n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249534
PNG
(US10072016, Compound 132 | US9434727, 132 | US9777...)
Show SMILES Fc1cc(F)c(c(c1)C1CCN(CC1)C(=O)c1nnc2ccc(cn12)C#N)C(F)(F)F
Show InChI InChI=1S/C20H14F5N5O/c21-13-7-14(17(15(22)8-13)20(23,24)25)12-3-5-29(6-4-12)19(31)18-28-27-16-2-1-11(9-26)10-30(16)18/h1-2,7-8,10,12H,3-6H2
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249513
PNG
(US10072016, Compound 111 | US9434727, 111 | US9777...)
Show SMILES CCN1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1ccc(F)c(F)c1C(F)(F)F
Show InChI InChI=1S/C21H23F5N4O/c1-2-29-8-7-14-16(11-29)27-28-19(14)20(31)30-9-5-12(6-10-30)13-3-4-15(22)18(23)17(13)21(24,25)26/h3-4,12H,2,5-11H2,1H3,(H,27,28)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249476
PNG
(US10072016, Compound 75 | US9434727, 75 | US977701...)
Show SMILES CCN1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1cccc(F)c1C(F)(F)F
Show InChI InChI=1S/C21H24F4N4O/c1-2-28-9-8-15-17(12-28)26-27-19(15)20(30)29-10-6-13(7-11-29)14-4-3-5-16(22)18(14)21(23,24)25/h3-5,13H,2,6-12H2,1H3,(H,26,27)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249496
PNG
(US10072016, Compound 94 | US9434727, 94 | US977701...)
Show SMILES COCCN1CCc2[nH]nc(C(=O)N3CCC(CC3)c3ccc(F)c(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C22H25F5N4O2/c1-33-11-10-30-7-6-17-15(12-30)20(29-28-17)21(32)31-8-4-13(5-9-31)14-2-3-16(23)19(24)18(14)22(25,26)27/h2-3,13H,4-12H2,1H3,(H,28,29)
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n/an/a 6.96n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249493
PNG
(US10072016, Compound 91 | US9434727, 91 | US977701...)
Show SMILES COC(=O)N1CCc2[nH]nc(C(=O)N3CCC(CC3)c3ccc(F)c(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C21H21F5N4O3/c1-33-20(32)30-9-6-15-13(10-30)18(28-27-15)19(31)29-7-4-11(5-8-29)12-2-3-14(22)17(23)16(12)21(24,25)26/h2-3,11H,4-10H2,1H3,(H,27,28)
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n/an/a 7.06n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249477
PNG
(US10072016, Compound 76 | US9434727, 76 | US977701...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(CCC(F)(F)F)CCc23)c1C(F)(F)F
Show InChI InChI=1S/C22H23F7N4O/c23-16-3-1-2-14(18(16)22(27,28)29)13-4-9-33(10-5-13)20(34)19-15-6-8-32(11-7-21(24,25)26)12-17(15)30-31-19/h1-3,13H,4-12H2,(H,30,31)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249503
PNG
(US10072016, Compound 101 | US9434727, 101 | US9777...)
Show SMILES COC(=O)N1Cc2[nH]nc(C(=O)N3CCC(CC3)c3ccc(F)c(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C20H19F5N4O3/c1-32-19(31)29-8-12-14(9-29)26-27-17(12)18(30)28-6-4-10(5-7-28)11-2-3-13(21)16(22)15(11)20(23,24)25/h2-3,10H,4-9H2,1H3,(H,26,27)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249467
PNG
(US10072016, Compound 66 | US9434727, 66 | US977701...)
Show SMILES CNC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1cccc(F)c1C(F)(F)F
Show InChI InChI=1S/C21H23F4N5O2/c1-26-20(32)30-10-7-14-16(11-30)27-28-18(14)19(31)29-8-5-12(6-9-29)13-3-2-4-15(22)17(13)21(23,24)25/h2-4,12H,5-11H2,1H3,(H,26,32)(H,27,28)
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n/an/a 7.5n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249547
PNG
(US10072016, Compound 145 | US9434727, 145 | US9777...)
Show SMILES Fc1ccc(Cl)c(c1)C1CCN(CC1)C(=O)c1nnc2ccc(cn12)C#N
Show InChI InChI=1S/C19H15ClFN5O/c20-16-3-2-14(21)9-15(16)13-5-7-25(8-6-13)19(27)18-24-23-17-4-1-12(10-22)11-26(17)18/h1-4,9,11,13H,5-8H2
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n/an/a 7.57n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249497
PNG
(US10072016, Compound 95 | US9434727, 95 | US977701...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CCN(Cc23)C#N)c(c1F)C(F)(F)F
Show InChI InChI=1S/C20H18F5N5O/c21-14-2-1-12(16(17(14)22)20(23,24)25)11-3-7-30(8-4-11)19(31)18-13-9-29(10-26)6-5-15(13)27-28-18/h1-2,11H,3-9H2,(H,27,28)
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n/an/a 7.78n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249489
PNG
(US10072016, Compound 87 | US9434727, 87 | US977701...)
Show SMILES CCN1CCc2[nH]nc(C(=O)N3CCC(CC3)c3ccc(F)c(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C21H23F5N4O/c1-2-29-8-7-16-14(11-29)19(28-27-16)20(31)30-9-5-12(6-10-30)13-3-4-15(22)18(23)17(13)21(24,25)26/h3-4,12H,2,5-11H2,1H3,(H,27,28)
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n/an/a 7.80n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249474
PNG
(US10072016, Compound 77 | US9434727, 73 | US943472...)
Show SMILES COCCN1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1cccc(F)c1C(F)(F)F
Show InChI InChI=1S/C22H26F4N4O2/c1-32-12-11-29-8-7-16-18(13-29)27-28-20(16)21(31)30-9-5-14(6-10-30)15-3-2-4-17(23)19(15)22(24,25)26/h2-4,14H,5-13H2,1H3,(H,27,28)
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n/an/a 7.96n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249495
PNG
(US10072016, Compound 93 | US9434727, 93 | US977701...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CCN(CCC(F)(F)F)Cc23)c(c1F)C(F)(F)F
Show InChI InChI=1S/C22H22F8N4O/c23-15-2-1-13(17(18(15)24)22(28,29)30)12-3-8-34(9-4-12)20(35)19-14-11-33(10-6-21(25,26)27)7-5-16(14)31-32-19/h1-2,12H,3-11H2,(H,31,32)
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n/an/a 8n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249561
PNG
(US10072016, Compound 159 | US9434727, 159 | US9777...)
Show SMILES CS(=O)(=O)N1CCc2[nH]nc(C(=O)N3CCC(CC3)c3ccc(F)cc3C(F)(F)F)c2C1
Show InChI InChI=1S/C20H22F4N4O3S/c1-32(30,31)28-9-6-17-15(11-28)18(26-25-17)19(29)27-7-4-12(5-8-27)14-3-2-13(21)10-16(14)20(22,23)24/h2-3,10,12H,4-9,11H2,1H3,(H,25,26)
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n/an/a 8.06n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249468
PNG
(US10072016, Compound 67 | US9434727, 67 | US977701...)
Show SMILES CCN1CCc2[nH]nc(C(=O)N3CCC(CC3)c3cccc(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C21H24F4N4O/c1-2-28-9-8-17-15(12-28)19(27-26-17)20(30)29-10-6-13(7-11-29)14-4-3-5-16(22)18(14)21(23,24)25/h3-5,13H,2,6-12H2,1H3,(H,26,27)
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n/an/a 8.31n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249474
PNG
(US10072016, Compound 77 | US9434727, 73 | US943472...)
Show SMILES COCCN1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1cccc(F)c1C(F)(F)F
Show InChI InChI=1S/C22H26F4N4O2/c1-32-12-11-29-8-7-16-18(13-29)27-28-20(16)21(31)30-9-5-14(6-10-30)15-3-2-4-17(23)19(15)22(24,25)26/h2-4,14H,5-13H2,1H3,(H,27,28)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249515
PNG
(US10072016, Compound 113 | US9434727, 113 | US9777...)
Show SMILES CN1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1ccc(F)c(F)c1C(F)(F)F
Show InChI InChI=1S/C20H21F5N4O/c1-28-7-6-13-15(10-28)26-27-18(13)19(30)29-8-4-11(5-9-29)12-2-3-14(21)17(22)16(12)20(23,24)25/h2-3,11H,4-10H2,1H3,(H,26,27)
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n/an/a 8.57n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249560
PNG
(US10072016, Compound 158 | US9434727, 158 | US9777...)
Show SMILES CC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1ccc(F)cc1C(F)(F)F
Show InChI InChI=1S/C21H22F4N4O2/c1-12(30)29-9-6-16-18(11-29)26-27-19(16)20(31)28-7-4-13(5-8-28)15-3-2-14(22)10-17(15)21(23,24)25/h2-3,10,13H,4-9,11H2,1H3,(H,26,27)
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n/an/a 8.63n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249545
PNG
(US10072016, Compound 143 | US9434727, 143 | US9777...)
Show SMILES CC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1cc(F)ccc1Cl
Show InChI InChI=1S/C20H22ClFN4O2/c1-12(27)26-9-6-15-18(11-26)23-24-19(15)20(28)25-7-4-13(5-8-25)16-10-14(22)2-3-17(16)21/h2-3,10,13H,4-9,11H2,1H3,(H,23,24)
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n/an/a 8.83n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249491
PNG
(US10072016, Compound 89 | US9434727, 89 | US977701...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CCN(Cc23)C2COC2)c(c1F)C(F)(F)F
Show InChI InChI=1S/C22H23F5N4O2/c23-16-2-1-14(18(19(16)24)22(25,26)27)12-3-6-30(7-4-12)21(32)20-15-9-31(13-10-33-11-13)8-5-17(15)28-29-20/h1-2,12-13H,3-11H2,(H,28,29)
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n/an/a 8.84n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249523
PNG
(US10072016, Compound 121 | US9434727, 121 | US9777...)
Show SMILES CC(C)C(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1ccc(F)c(F)c1C(F)(F)F
Show InChI InChI=1S/C23H25F5N4O2/c1-12(2)21(33)32-10-7-15-17(11-32)29-30-20(15)22(34)31-8-5-13(6-9-31)14-3-4-16(24)19(25)18(14)23(26,27)28/h3-4,12-13H,5-11H2,1-2H3,(H,29,30)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249562
PNG
(US10072016, Compound 160 | US9434727, 160 | US9777...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2nnc3ccc(cn23)C#N)c(c1)C(F)(F)F
Show InChI InChI=1S/C20H15F4N5O/c21-14-2-3-15(16(9-14)20(22,23)24)13-5-7-28(8-6-13)19(30)18-27-26-17-4-1-12(10-25)11-29(17)18/h1-4,9,11,13H,5-8H2
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n/an/a 9.06n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249482
PNG
(US10072016, Compound 81 | US9434727, 80 | US943472...)
Show SMILES CC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1ccc(F)c(F)c1C(F)(F)F
Show InChI InChI=1S/C21H21F5N4O2/c1-11(31)30-9-6-14-16(10-30)27-28-19(14)20(32)29-7-4-12(5-8-29)13-2-3-15(22)18(23)17(13)21(24,25)26/h2-3,12H,4-10H2,1H3,(H,27,28)
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n/an/a 9.12n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249542
PNG
(US10072016, Compound 140 | US9434727, 140 | US9777...)
Show SMILES CC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1cc(F)ccc1C(F)(F)F
Show InChI InChI=1S/C21H22F4N4O2/c1-12(30)29-9-6-15-18(11-29)26-27-19(15)20(31)28-7-4-13(5-8-28)16-10-14(22)2-3-17(16)21(23,24)25/h2-3,10,13H,4-9,11H2,1H3,(H,26,27)
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n/an/a 9.28n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249520
PNG
(US10072016, Compound 118 | US9434727, 118 | US9777...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(CC4CC4)CCc23)c(c1F)C(F)(F)F
Show InChI InChI=1S/C23H25F5N4O/c24-17-4-3-15(19(20(17)25)23(26,27)28)14-5-9-32(10-6-14)22(33)21-16-7-8-31(11-13-1-2-13)12-18(16)29-30-21/h3-4,13-14H,1-2,5-12H2,(H,29,30)
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n/an/a 9.39n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249489
PNG
(US10072016, Compound 87 | US9434727, 87 | US977701...)
Show SMILES CCN1CCc2[nH]nc(C(=O)N3CCC(CC3)c3ccc(F)c(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C21H23F5N4O/c1-2-29-8-7-16-14(11-29)19(28-27-16)20(31)30-9-5-12(6-10-30)13-3-4-15(22)18(23)17(13)21(24,25)26/h3-4,12H,2,5-11H2,1H3,(H,27,28)
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n/an/a 9.46n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249480
PNG
(US10072016, Compound 78 | US9434727, 78 | US977701...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(CCc23)C2COC2)c1C(F)(F)F
Show InChI InChI=1S/C22H24F4N4O2/c23-17-3-1-2-15(19(17)22(24,25)26)13-4-7-29(8-5-13)21(31)20-16-6-9-30(14-11-32-12-14)10-18(16)27-28-20/h1-3,13-14H,4-12H2,(H,27,28)
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n/an/a 9.5n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249470
PNG
(US10072016, Compound 69 | US9434727, 69 | US977701...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CCN(CC4CC4)Cc23)c1C(F)(F)F
Show InChI InChI=1S/C23H26F4N4O/c24-18-3-1-2-16(20(18)23(25,26)27)15-6-10-31(11-7-15)22(32)21-17-13-30(12-14-4-5-14)9-8-19(17)28-29-21/h1-3,14-15H,4-13H2,(H,28,29)
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n/an/a 10n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249540
PNG
(US10072016, Compound 138 | US9434727, 138 | US9777...)
Show SMILES COC(=O)N1CCc2[nH]nc(C(=O)N3CCC(CC3)c3cc(F)cc(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C21H21F5N4O3/c1-33-20(32)30-7-4-16-14(10-30)18(28-27-16)19(31)29-5-2-11(3-6-29)13-8-12(22)9-15(23)17(13)21(24,25)26/h8-9,11H,2-7,10H2,1H3,(H,27,28)
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n/an/a 10.1n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249494
PNG
(US10072016, Compound 92 | US9434727, 92 | US977701...)
Show SMILES CNC(=O)N1CCc2[nH]nc(C(=O)N3CCC(CC3)c3ccc(F)c(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C21H22F5N5O2/c1-27-20(33)31-9-6-15-13(10-31)18(29-28-15)19(32)30-7-4-11(5-8-30)12-2-3-14(22)17(23)16(12)21(24,25)26/h2-3,11H,4-10H2,1H3,(H,27,33)(H,28,29)
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n/an/a 10.2n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249516
PNG
(US10072016, Compound 114 | US9434727, 114 | US9777...)
Show SMILES CNC(=O)N1CCc2[nH]nc(C(=O)N3CCC(CC3)c3cccc(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C21H23F4N5O2/c1-26-20(32)30-10-7-16-14(11-30)18(28-27-16)19(31)29-8-5-12(6-9-29)13-3-2-4-15(22)17(13)21(23,24)25/h2-4,12H,5-11H2,1H3,(H,26,32)(H,27,28)
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n/an/a 10.3n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249553
PNG
(US10072016, Compound 151 | US9434727, 151 | US9777...)
Show SMILES CS(=O)(=O)N1CCc2[nH]nc(C(=O)N3CCC(CC3)c3cccc(F)c3Cl)c2C1
Show InChI InChI=1S/C19H22ClFN4O3S/c1-29(27,28)25-10-7-16-14(11-25)18(23-22-16)19(26)24-8-5-12(6-9-24)13-3-2-4-15(21)17(13)20/h2-4,12H,5-11H2,1H3,(H,22,23)
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n/an/a 10.3n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249521
PNG
(US10072016, Compound 119 | US9434727, 119 | US9777...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(CCC(F)(F)F)CCc23)c(c1F)C(F)(F)F
Show InChI InChI=1S/C22H22F8N4O/c23-15-2-1-13(17(18(15)24)22(28,29)30)12-3-8-34(9-4-12)20(35)19-14-5-7-33(10-6-21(25,26)27)11-16(14)31-32-19/h1-2,12H,3-11H2,(H,31,32)
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n/an/a 10.7n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249473
PNG
(US10072016, Compound 72 | US9434727, 72 | US977701...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CCN(CCC(F)(F)F)Cc23)c1C(F)(F)F
Show InChI InChI=1S/C22H23F7N4O/c23-16-3-1-2-14(18(16)22(27,28)29)13-4-9-33(10-5-13)20(34)19-15-12-32(11-7-21(24,25)26)8-6-17(15)30-31-19/h1-3,13H,4-12H2,(H,30,31)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249460
PNG
(US10072016, Compound 36 | US9434727, 36 | US977701...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CCNCc23)c(c1F)C(F)(F)F
Show InChI InChI=1S/C19H19F5N4O/c20-13-2-1-11(15(16(13)21)19(22,23)24)10-4-7-28(8-5-10)18(29)17-12-9-25-6-3-14(12)26-27-17/h1-2,10,25H,3-9H2,(H,26,27)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249507
PNG
(US10072016, Compound 105 | US9434727, 105 | US9777...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(Cc23)C(=O)c2ccncc2)c(c1F)C(F)(F)F
Show InChI InChI=1S/C24H20F5N5O2/c25-17-2-1-15(19(20(17)26)24(27,28)29)13-5-9-33(10-6-13)23(36)21-16-11-34(12-18(16)31-32-21)22(35)14-3-7-30-8-4-14/h1-4,7-8,13H,5-6,9-12H2,(H,31,32)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249518
PNG
(US10072016, Compound 116 | US9434727, 116 | US9777...)
Show SMILES COC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1ccc(F)c(F)c1C(F)(F)F
Show InChI InChI=1S/C21H21F5N4O3/c1-33-20(32)30-9-6-13-15(10-30)27-28-18(13)19(31)29-7-4-11(5-8-29)12-2-3-14(22)17(23)16(12)21(24,25)26/h2-3,11H,4-10H2,1H3,(H,27,28)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249514
PNG
(US10072016, Compound 112 | US9434727, 112 | US9777...)
Show SMILES CNC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1ccc(F)c(F)c1C(F)(F)F
Show InChI InChI=1S/C21H22F5N5O2/c1-27-20(33)31-9-6-13-15(10-31)28-29-18(13)19(32)30-7-4-11(5-8-30)12-2-3-14(22)17(23)16(12)21(24,25)26/h2-3,11H,4-10H2,1H3,(H,27,33)(H,28,29)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249485
PNG
(US10072016, Compound 83 | US9434727, 83 | US977701...)
Show SMILES CC(=O)N1Cc2[nH]nc(C(=O)N3CCC(CC3)c3ccc(F)c(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C20H19F5N4O2/c1-10(30)29-8-13-15(9-29)26-27-18(13)19(31)28-6-4-11(5-7-28)12-2-3-14(21)17(22)16(12)20(23,24)25/h2-3,11H,4-9H2,1H3,(H,26,27)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249475
PNG
(US10072016, Compound 74 | US9434727, 74 | US977701...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CCN(Cc23)C2COC2)c1C(F)(F)F
Show InChI InChI=1S/C22H24F4N4O2/c23-17-3-1-2-15(19(17)22(24,25)26)13-4-7-29(8-5-13)21(31)20-16-10-30(14-11-32-12-14)9-6-18(16)27-28-20/h1-3,13-14H,4-12H2,(H,27,28)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249484
PNG
(US10072016, Compound 82 | US9434727, 82 | US977701...)
Show SMILES CC(=O)N1CCc2[nH]nc(C(=O)N3CCC(CC3)c3ccc(F)c(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C21H21F5N4O2/c1-11(31)30-9-6-16-14(10-30)19(28-27-16)20(32)29-7-4-12(5-8-29)13-2-3-15(22)18(23)17(13)21(24,25)26/h2-3,12H,4-10H2,1H3,(H,27,28)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249569
PNG
(US10072016, Compound 167 | US9434727, 167 | US9777...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CCN(CCC(F)(F)F)Cc23)c1Cl
Show InChI InChI=1S/C21H23ClF4N4O/c22-18-14(2-1-3-16(18)23)13-4-9-30(10-5-13)20(31)19-15-12-29(11-7-21(24,25)26)8-6-17(15)27-28-19/h1-3,13H,4-12H2,(H,27,28)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249500
PNG
(US10072016, Compound 98 | US9434727, 98 | US977701...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(Cc23)C2COC2)c(c1F)C(F)(F)F
Show InChI InChI=1S/C21H21F5N4O2/c22-15-2-1-13(17(18(15)23)21(24,25)26)11-3-5-29(6-4-11)20(31)19-14-7-30(12-9-32-10-12)8-16(14)27-28-19/h1-2,11-12H,3-10H2,(H,27,28)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249568
PNG
(US10072016, Compound 166 | US9434727, 166 | US9777...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CCN(CC(F)(F)F)Cc23)c1Cl
Show InChI InChI=1S/C20H21ClF4N4O/c21-17-13(2-1-3-15(17)22)12-4-8-29(9-5-12)19(30)18-14-10-28(11-20(23,24)25)7-6-16(14)26-27-18/h1-3,12H,4-11H2,(H,26,27)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249498
PNG
(US10072016, Compound 96 | US9434727, 96 | US977701...)
Show SMILES CCN1Cc2[nH]nc(C(=O)N3CCC(CC3)c3ccc(F)c(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C20H21F5N4O/c1-2-28-9-13-15(10-28)26-27-18(13)19(30)29-7-5-11(6-8-29)12-3-4-14(21)17(22)16(12)20(23,24)25/h3-4,11H,2,5-10H2,1H3,(H,26,27)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249532
PNG
(US10072016, Compound 130 | US9434727, 130 | US9777...)
Show SMILES COC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1cc(F)cc(F)c1C(F)(F)F
Show InChI InChI=1S/C21H21F5N4O3/c1-33-20(32)30-7-4-13-16(10-30)27-28-18(13)19(31)29-5-2-11(3-6-29)14-8-12(22)9-15(23)17(14)21(24,25)26/h8-9,11H,2-7,10H2,1H3,(H,27,28)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249457
PNG
(US10072016, Compound 30 | US9434727, 30 | US977701...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CNCCc23)c1C(F)(F)F
Show InChI InChI=1S/C19H20F4N4O/c20-14-3-1-2-12(16(14)19(21,22)23)11-5-8-27(9-6-11)18(28)17-13-4-7-24-10-15(13)25-26-17/h1-3,11,24H,4-10H2,(H,25,26)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249490
PNG
(US10072016, Compound 88 | US9434727, 88 | US977701...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CCN(CC4CC4)Cc23)c(c1F)C(F)(F)F
Show InChI InChI=1S/C23H25F5N4O/c24-17-4-3-15(19(20(17)25)23(26,27)28)14-5-9-32(10-6-14)22(33)21-16-12-31(11-13-1-2-13)8-7-18(16)29-30-21/h3-4,13-14H,1-2,5-12H2,(H,29,30)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249566
PNG
(US10072016, Compound 164 | US9434727, 164 | US9777...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CCN(CC4CC4)Cc23)c1Cl
Show InChI InChI=1S/C22H26ClFN4O/c23-20-16(2-1-3-18(20)24)15-6-10-28(11-7-15)22(29)21-17-13-27(12-14-4-5-14)9-8-19(17)25-26-21/h1-3,14-15H,4-13H2,(H,25,26)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249531
PNG
(US10072016, Compound 129 | US9434727, 129 | US9777...)
Show SMILES Fc1cc(F)c(c(c1)C1CCN(CC1)C(=O)c1n[nH]c2CCN(CCC(F)(F)F)Cc12)C(F)(F)F
Show InChI InChI=1S/C22H22F8N4O/c23-13-9-14(18(16(24)10-13)22(28,29)30)12-1-6-34(7-2-12)20(35)19-15-11-33(8-4-21(25,26)27)5-3-17(15)31-32-19/h9-10,12H,1-8,11H2,(H,31,32)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249462
PNG
(US10072016, Compound 40 | US9434727, 40 | US977701...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CNCCc23)c1Cl
Show InChI InChI=1S/C18H20ClFN4O/c19-16-12(2-1-3-14(16)20)11-5-8-24(9-6-11)18(25)17-13-4-7-21-10-15(13)22-23-17/h1-3,11,21H,4-10H2,(H,22,23)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249499
PNG
(US10072016, Compound 97 | US9434727, 97 | US977701...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(CC4CC4)Cc23)c(c1F)C(F)(F)F
Show InChI InChI=1S/C22H23F5N4O/c23-16-4-3-14(18(19(16)24)22(25,26)27)13-5-7-31(8-6-13)21(32)20-15-10-30(9-12-1-2-12)11-17(15)28-29-20/h3-4,12-13H,1-2,5-11H2,(H,28,29)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249492
PNG
(US10072016, Compound 90 | US9434727, 90 | US977701...)
Show SMILES CC(C)(C)CN1CCc2[nH]nc(C(=O)N3CCC(CC3)c3ccc(F)c(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C24H29F5N4O/c1-23(2,3)13-32-9-8-18-16(12-32)21(31-30-18)22(34)33-10-6-14(7-11-33)15-4-5-17(25)20(26)19(15)24(27,28)29/h4-5,14H,6-13H2,1-3H3,(H,30,31)
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n/an/a 14.4n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249526
PNG
(US10072016, Compound 124 | US9434727, 124 | US9777...)
Show SMILES COCCN1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1ccc(F)c(F)c1C(F)(F)F
Show InChI InChI=1S/C22H25F5N4O2/c1-33-11-10-30-7-6-15-17(12-30)28-29-20(15)21(32)31-8-4-13(5-9-31)14-2-3-16(23)19(24)18(14)22(25,26)27/h2-3,13H,4-12H2,1H3,(H,28,29)
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n/an/a 14.6n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249490
PNG
(US10072016, Compound 88 | US9434727, 88 | US977701...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CCN(CC4CC4)Cc23)c(c1F)C(F)(F)F
Show InChI InChI=1S/C23H25F5N4O/c24-17-4-3-15(19(20(17)25)23(26,27)28)14-5-9-32(10-6-14)22(33)21-16-12-31(11-13-1-2-13)8-7-18(16)29-30-21/h3-4,13-14H,1-2,5-12H2,(H,29,30)
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n/an/a 14.7n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249511
PNG
(US10072016, Compound 109 | US9434727, 109 | US9777...)
Show SMILES COCCN1Cc2[nH]nc(C(=O)N3CCC(CC3)c3ccc(F)c(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C21H23F5N4O2/c1-32-9-8-29-10-14-16(11-29)27-28-19(14)20(31)30-6-4-12(5-7-30)13-2-3-15(22)18(23)17(13)21(24,25)26/h2-3,12H,4-11H2,1H3,(H,27,28)
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n/an/a 14.9n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249527
PNG
(US10072016, Compound 125 | US9434727, 125 | US9777...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(CC(F)(F)F)CCc23)c(c1F)C(F)(F)F
Show InChI InChI=1S/C21H20F8N4O/c22-14-2-1-12(16(17(14)23)21(27,28)29)11-3-7-33(8-4-11)19(34)18-13-5-6-32(10-20(24,25)26)9-15(13)30-31-18/h1-2,11H,3-10H2,(H,30,31)
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n/an/a 15n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249525
PNG
(US10072016, Compound 123 | US9434727, 123 | US9777...)
Show SMILES CC(C)CC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1ccc(F)c(F)c1C(F)(F)F
Show InChI InChI=1S/C24H27F5N4O2/c1-13(2)11-19(34)33-10-7-16-18(12-33)30-31-22(16)23(35)32-8-5-14(6-9-32)15-3-4-17(25)21(26)20(15)24(27,28)29/h3-4,13-14H,5-12H2,1-2H3,(H,30,31)
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n/an/a 15.1n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249565
PNG
(US10072016, Compound 163 | US9434727, 163 | US9777...)
Show SMILES CCN1CCc2[nH]nc(C(=O)N3CCC(CC3)c3cccc(F)c3Cl)c2C1
Show InChI InChI=1S/C20H24ClFN4O/c1-2-25-9-8-17-15(12-25)19(24-23-17)20(27)26-10-6-13(7-11-26)14-4-3-5-16(22)18(14)21/h3-5,13H,2,6-12H2,1H3,(H,23,24)
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n/an/a 15.3n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249570
PNG
(US10072016, Compound 168 | US9434727, 168 | US9777...)
Show SMILES COCCN1CCc2[nH]nc(C(=O)N3CCC(CC3)c3cccc(F)c3Cl)c2C1
Show InChI InChI=1S/C21H26ClFN4O2/c1-29-12-11-26-8-7-18-16(13-26)20(25-24-18)21(28)27-9-5-14(6-10-27)15-3-2-4-17(23)19(15)22/h2-4,14H,5-13H2,1H3,(H,24,25)
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n/an/a 15.5n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249567
PNG
(US10072016, Compound 165 | US9434727, 165 | US9777...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CCN(Cc23)C2COC2)c1Cl
Show InChI InChI=1S/C21H24ClFN4O2/c22-19-15(2-1-3-17(19)23)13-4-7-26(8-5-13)21(28)20-16-10-27(14-11-29-12-14)9-6-18(16)24-25-20/h1-3,13-14H,4-12H2,(H,24,25)
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n/an/a 15.6n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249512
PNG
(US10072016, Compound 110 | US9434727, 110 | US9777...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(Cc23)C#N)c(c1F)C(F)(F)F
Show InChI InChI=1S/C19H16F5N5O/c20-13-2-1-11(15(16(13)21)19(22,23)24)10-3-5-29(6-4-10)18(30)17-12-7-28(9-25)8-14(12)26-27-17/h1-2,10H,3-8H2,(H,26,27)
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n/an/a 15.6n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249529
PNG
(US10072016, Compound 127 | US9434727, 127 | US9777...)
Show SMILES COCCN1CCc2[nH]nc(C(=O)N3CCC(CC3)c3cc(F)cc(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C22H25F5N4O2/c1-33-9-8-30-5-4-18-16(12-30)20(29-28-18)21(32)31-6-2-13(3-7-31)15-10-14(23)11-17(24)19(15)22(25,26)27/h10-11,13H,2-9,12H2,1H3,(H,28,29)
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n/an/a 15.9n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249548
PNG
(US10072016, Compound 146 | US9434727, 146 | US9777...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(CC4CC4)CCc23)c1Cl
Show InChI InChI=1S/C22H26ClFN4O/c23-20-16(2-1-3-18(20)24)15-6-10-28(11-7-15)22(29)21-17-8-9-27(12-14-4-5-14)13-19(17)25-26-21/h1-3,14-15H,4-13H2,(H,25,26)
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n/an/a 15.9n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249505
PNG
(US10072016, Compound 103 | US9434727, 103 | US9777...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(Cc23)C(=O)c2ccccn2)c(c1F)C(F)(F)F
Show InChI InChI=1S/C24H20F5N5O2/c25-16-5-4-14(19(20(16)26)24(27,28)29)13-6-9-33(10-7-13)23(36)21-15-11-34(12-18(15)31-32-21)22(35)17-3-1-2-8-30-17/h1-5,8,13H,6-7,9-12H2,(H,31,32)
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n/an/a 16n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249486
PNG
(US10072016, Compound 84 | US9434727, 84 | US977701...)
Show SMILES CCC(=O)N1Cc2[nH]nc(C(=O)N3CCC(CC3)c3ccc(F)c(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C21H21F5N4O2/c1-2-16(31)30-9-13-15(10-30)27-28-19(13)20(32)29-7-5-11(6-8-29)12-3-4-14(22)18(23)17(12)21(24,25)26/h3-4,11H,2,5-10H2,1H3,(H,27,28)
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n/an/a 16.3n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249471
PNG
(US10072016, Compound 70 | US9434727, 70 | US977701...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CCN(Cc23)C#N)c1C(F)(F)F
Show InChI InChI=1S/C20H19F4N5O/c21-15-3-1-2-13(17(15)20(22,23)24)12-4-8-29(9-5-12)19(30)18-14-10-28(11-25)7-6-16(14)26-27-18/h1-3,12H,4-10H2,(H,26,27)
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n/an/a 16.4n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249537
PNG
(US10072016, Compound 135 | US9434727, 135 | US9777...)
Show SMILES Fc1cc(F)c(c(c1)C1CCN(CC1)C(=O)c1n[nH]c2CN(CCc12)C1COC1)C(F)(F)F
Show InChI InChI=1S/C22H23F5N4O2/c23-13-7-16(19(17(24)8-13)22(25,26)27)12-1-4-30(5-2-12)21(32)20-15-3-6-31(14-10-33-11-14)9-18(15)28-29-20/h7-8,12,14H,1-6,9-11H2,(H,28,29)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249538
PNG
(US10072016, Compound 136 | US9434727, 136 | US9777...)
Show SMILES Fc1cc(F)c(c(c1)C1CCN(CC1)C(=O)c1n[nH]c2CN(CCc12)C#N)C(F)(F)F
Show InChI InChI=1S/C20H18F5N5O/c21-12-7-14(17(15(22)8-12)20(23,24)25)11-1-5-30(6-2-11)19(31)18-13-3-4-29(10-26)9-16(13)27-28-18/h7-8,11H,1-6,9H2,(H,27,28)
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n/an/a 16.7n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249528
PNG
(US10072016, Compound 126 | US9434727, 126 | US9777...)
Show SMILES CC(C)(C)CN1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1ccc(F)c(F)c1C(F)(F)F
Show InChI InChI=1S/C24H29F5N4O/c1-23(2,3)13-32-9-8-16-18(12-32)30-31-21(16)22(34)33-10-6-14(7-11-33)15-4-5-17(25)20(26)19(15)24(27,28)29/h4-5,14H,6-13H2,1-3H3,(H,30,31)
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n/an/a 17n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249524
PNG
(US10072016, Compound 122 | US9434727, 122 | US9777...)
Show SMILES CCC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1ccc(F)c(F)c1C(F)(F)F
Show InChI InChI=1S/C22H23F5N4O2/c1-2-17(32)31-10-7-14-16(11-31)28-29-20(14)21(33)30-8-5-12(6-9-30)13-3-4-15(23)19(24)18(13)22(25,26)27/h3-4,12H,2,5-11H2,1H3,(H,28,29)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249472
PNG
(US10072016, Compound 71 | US9434727, 71 | US977701...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CCN(CC(F)(F)F)Cc23)c1C(F)(F)F
Show InChI InChI=1S/C21H21F7N4O/c22-15-3-1-2-13(17(15)21(26,27)28)12-4-8-32(9-5-12)19(33)18-14-10-31(11-20(23,24)25)7-6-16(14)29-30-18/h1-3,12H,4-11H2,(H,29,30)
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n/an/a 17.1n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249549
PNG
(US10072016, Compound 147 | US9434727, 147 | US9777...)
Show SMILES COC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1cccc(F)c1Cl
Show InChI InChI=1S/C20H22ClFN4O3/c1-29-20(28)26-10-7-14-16(11-26)23-24-18(14)19(27)25-8-5-12(6-9-25)13-3-2-4-15(22)17(13)21/h2-4,12H,5-11H2,1H3,(H,23,24)
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n/an/a 17.1n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249536
PNG
(US10072016, Compound 134 | US9434727, 134 | US9777...)
Show SMILES Fc1cc(F)c(c(c1)C1CCN(CC1)C(=O)c1n[nH]c2CN(CC3CC3)CCc12)C(F)(F)F
Show InChI InChI=1S/C23H25F5N4O/c24-15-9-17(20(18(25)10-15)23(26,27)28)14-3-7-32(8-4-14)22(33)21-16-5-6-31(11-13-1-2-13)12-19(16)29-30-21/h9-10,13-14H,1-8,11-12H2,(H,29,30)
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n/an/a 17.2n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249541
PNG
(US10072016, Compound 139 | US9434727, 139 | US9777...)
Show SMILES CNC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1cc(F)cc(F)c1C(F)(F)F
Show InChI InChI=1S/C21H22F5N5O2/c1-27-20(33)31-7-4-13-16(10-31)28-29-18(13)19(32)30-5-2-11(3-6-30)14-8-12(22)9-15(23)17(14)21(24,25)26/h8-9,11H,2-7,10H2,1H3,(H,27,33)(H,28,29)
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n/an/a 17.8n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249487
PNG
(US10072016, Compound 85 | US9434727, 85 | US977701...)
Show SMILES CC(C)C(=O)N1Cc2[nH]nc(C(=O)N3CCC(CC3)c3ccc(F)c(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C22H23F5N4O2/c1-11(2)20(32)31-9-14-16(10-31)28-29-19(14)21(33)30-7-5-12(6-8-30)13-3-4-15(23)18(24)17(13)22(25,26)27/h3-4,11-12H,5-10H2,1-2H3,(H,28,29)
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n/an/a 17.9n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249530
PNG
(US10072016, Compound 128 | US9434727, 128 | US9777...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(Cc23)C(=O)N2CCCCC2)c(c1F)C(F)(F)F
Show InChI InChI=1S/C24H26F5N5O2/c25-17-5-4-15(19(20(17)26)24(27,28)29)14-6-10-32(11-7-14)22(35)21-16-12-34(13-18(16)30-31-21)23(36)33-8-2-1-3-9-33/h4-5,14H,1-3,6-13H2,(H,30,31)
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n/an/a 18.4n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249539
PNG
(US10072016, Compound 137 | US9434727, 137 | US9777...)
Show SMILES Fc1cc(F)c(c(c1)C1CCN(CC1)C(=O)c1n[nH]c2CN(CC(F)(F)F)CCc12)C(F)(F)F
Show InChI InChI=1S/C21H20F8N4O/c22-12-7-14(17(15(23)8-12)21(27,28)29)11-1-5-33(6-2-11)19(34)18-13-3-4-32(10-20(24,25)26)9-16(13)30-31-18/h7-8,11H,1-6,9-10H2,(H,30,31)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249506
PNG
(US10072016, Compound 104 | US9434727, 104 | US9777...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(Cc23)C(=O)c2cccnc2)c(c1F)C(F)(F)F
Show InChI InChI=1S/C24H20F5N5O2/c25-17-4-3-15(19(20(17)26)24(27,28)29)13-5-8-33(9-6-13)23(36)21-16-11-34(12-18(16)31-32-21)22(35)14-2-1-7-30-10-14/h1-4,7,10,13H,5-6,8-9,11-12H2,(H,31,32)
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n/an/a 18.9n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249517
PNG
(US10072016, Compound 115 | US9434727, 115 | US9777...)
Show SMILES OC(=O)CN1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1ccc(F)c(F)c1C(F)(F)F
Show InChI InChI=1S/C21H21F5N4O3/c22-14-2-1-12(17(18(14)23)21(24,25)26)11-3-7-30(8-4-11)20(33)19-13-5-6-29(10-16(31)32)9-15(13)27-28-19/h1-2,11H,3-10H2,(H,27,28)(H,31,32)
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n/an/a 18.9n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249488
PNG
(US10072016, Compound 86 | US9434727, 86 | US977701...)
Show SMILES CC(C)CC(=O)N1Cc2[nH]nc(C(=O)N3CCC(CC3)c3ccc(F)c(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C23H25F5N4O2/c1-12(2)9-18(33)32-10-15-17(11-32)29-30-21(15)22(34)31-7-5-13(6-8-31)14-3-4-16(24)20(25)19(14)23(26,27)28/h3-4,12-13H,5-11H2,1-2H3,(H,29,30)
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n/an/a 19.3n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249558
PNG
(US10072016, Compound 156 | US9434727, 156 | US9777...)
Show SMILES CC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1c(F)cccc1C(F)(F)F
Show InChI InChI=1S/C21H22F4N4O2/c1-12(30)29-10-7-14-17(11-29)26-27-19(14)20(31)28-8-5-13(6-9-28)18-15(21(23,24)25)3-2-4-16(18)22/h2-4,13H,5-11H2,1H3,(H,26,27)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249502
PNG
(US10072016, Compound 100 | US9434727, 100 | US9777...)
Show SMILES CNC(=O)N1Cc2[nH]nc(C(=O)N3CCC(CC3)c3ccc(F)c(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C20H20F5N5O2/c1-26-19(32)30-8-12-14(9-30)27-28-17(12)18(31)29-6-4-10(5-7-29)11-2-3-13(21)16(22)15(11)20(23,24)25/h2-3,10H,4-9H2,1H3,(H,26,32)(H,27,28)
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n/an/a 19.6n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249508
PNG
(US10072016, Compound 106 | US9434727, 106 | US9777...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(Cc23)C(=O)N2CCCC2)c(c1F)C(F)(F)F
Show InChI InChI=1S/C23H24F5N5O2/c24-16-4-3-14(18(19(16)25)23(26,27)28)13-5-9-31(10-6-13)21(34)20-15-11-33(12-17(15)29-30-20)22(35)32-7-1-2-8-32/h3-4,13H,1-2,5-12H2,(H,29,30)
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n/an/a 20.4n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249459
PNG
(US10072016, Compound 34 | US9434727, 34 | US977701...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CNCCc23)c(c1F)C(F)(F)F
Show InChI InChI=1S/C19H19F5N4O/c20-13-2-1-11(15(16(13)21)19(22,23)24)10-4-7-28(8-5-10)18(29)17-12-3-6-25-9-14(12)26-27-17/h1-2,10,25H,3-9H2,(H,26,27)
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n/an/a 20.7n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249557
PNG
(US10072016, Compound 155 | US9434727, 155 | US9777...)
Show SMILES COc1ccc2nnc(C(=O)N3CCC(CC3)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)n2c1
Show InChI InChI=1S/C21H18F6N4O2/c1-33-16-2-3-17-28-29-18(31(17)11-16)19(32)30-6-4-12(5-7-30)13-8-14(20(22,23)24)10-15(9-13)21(25,26)27/h2-3,8-12H,4-7H2,1H3
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249504
PNG
(US10072016, Compound 102 | US9434727, 102 | US9777...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(Cc23)C(=O)c2ccccc2)c(c1F)C(F)(F)F
Show InChI InChI=1S/C25H21F5N4O2/c26-18-7-6-16(20(21(18)27)25(28,29)30)14-8-10-33(11-9-14)24(36)22-17-12-34(13-19(17)31-32-22)23(35)15-4-2-1-3-5-15/h1-7,14H,8-13H2,(H,31,32)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249501
PNG
(US10072016, Compound 99 | US9434727, 99 | US977701...)
Show SMILES CC(C)(C)CN1Cc2[nH]nc(C(=O)N3CCC(CC3)c3ccc(F)c(F)c3C(F)(F)F)c2C1
Show InChI InChI=1S/C23H27F5N4O/c1-22(2,3)12-31-10-15-17(11-31)29-30-20(15)21(33)32-8-6-13(7-9-32)14-4-5-16(24)19(25)18(14)23(26,27)28/h4-5,13H,6-12H2,1-3H3,(H,29,30)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249509
PNG
(US10072016, Compound 107 | US9434727, 107 | US9777...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(CC(F)(F)F)Cc23)c(c1F)C(F)(F)F
Show InChI InChI=1S/C20H18F8N4O/c21-13-2-1-11(15(16(13)22)20(26,27)28)10-3-5-32(6-4-10)18(33)17-12-7-31(9-19(23,24)25)8-14(12)29-30-17/h1-2,10H,3-9H2,(H,29,30)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249510
PNG
(US10072016, Compound 108 | US9434727, 108 | US9777...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(CCC(F)(F)F)Cc23)c(c1F)C(F)(F)F
Show InChI InChI=1S/C21H20F8N4O/c22-14-2-1-12(16(17(14)23)21(27,28)29)11-3-6-33(7-4-11)19(34)18-13-9-32(8-5-20(24,25)26)10-15(13)30-31-18/h1-2,11H,3-10H2,(H,30,31)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249461
PNG
(US10072016, Compound 38 | US9434727, 38 | US977701...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CNCc23)c(c1F)C(F)(F)F
Show InChI InChI=1S/C18H17F5N4O/c19-12-2-1-10(14(15(12)20)18(21,22)23)9-3-5-27(6-4-9)17(28)16-11-7-24-8-13(11)25-26-16/h1-2,9,24H,3-8H2,(H,25,26)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249571
PNG
(US10072016, Compound 169 | US9434727, 169 | US9777...)
Show SMILES Fc1ccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(Cc23)C(=O)N2CCNCC2)c(c1F)C(F)(F)F
Show InChI InChI=1S/C23H25F5N6O2/c24-16-2-1-14(18(19(16)25)23(26,27)28)13-3-7-32(8-4-13)21(35)20-15-11-34(12-17(15)30-31-20)22(36)33-9-5-29-6-10-33/h1-2,13,29H,3-12H2,(H,30,31)
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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249458
PNG
(US10072016, Compound 32 | US9434727, 32 | US977701...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CCNCc23)c1C(F)(F)F
Show InChI InChI=1S/C19H20F4N4O/c20-14-3-1-2-12(16(14)19(21,22)23)11-5-8-27(9-6-11)18(28)17-13-10-24-7-4-15(13)25-26-17/h1-3,11,24H,4-10H2,(H,25,26)
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MMDB

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n/an/a 62.5n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249555
PNG
(US10072016, Compound 153 | US9434727, 153 | US9777...)
Show SMILES CC(=O)N1CCc2c(C1)[nH]nc2C(=O)N1CCC(CC1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C22H22F6N4O2/c1-12(33)32-7-4-17-18(11-32)29-30-19(17)20(34)31-5-2-13(3-6-31)14-8-15(21(23,24)25)10-16(9-14)22(26,27)28/h8-10,13H,2-7,11H2,1H3,(H,29,30)
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n/an/a 149n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249556
PNG
(US10072016, Compound 154 | US9434727, 154 | US9777...)
Show SMILES CS(=O)(=O)N1CCc2[nH]nc(C(=O)N3CCC(CC3)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)c2C1
Show InChI InChI=1S/C21H22F6N4O3S/c1-35(33,34)31-7-4-17-16(11-31)18(29-28-17)19(32)30-5-2-12(3-6-30)13-8-14(20(22,23)24)10-15(9-13)21(25,26)27/h8-10,12H,2-7,11H2,1H3,(H,28,29)
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n/an/a 150n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
spa binding assay for rbp4


(Homo sapiens (Human))
BDBM249463
PNG
(US10072016, Compound 42 | US9434727, 42 | US977701...)
Show SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CCNCc23)c1Cl
Show InChI InChI=1S/C18H20ClFN4O/c19-16-12(2-1-3-14(16)20)11-5-8-24(9-6-11)18(25)17-13-10-21-7-4-15(13)22-23-17/h1-3,11,21H,4-10H2,(H,22,23)
PDB
MMDB

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n/an/a 424n/an/an/an/an/an/a



THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

US Patent


Assay Description
Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...


US Patent US9777010 (2017)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%