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Patent code US9796710

Compile Data Set for Download or QSAR
Found 47 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351594
PNG
(US9796710, Compound 4 | US9796710, Compound 5)
Show SMILES CCS(=O)(=O)c1ccc(nc1)[C@H](CO)NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@@H](OC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C27H35F3N4O5S/c1-4-40(37,38)20-6-7-21(31-11-20)22(14-35)33-26(36)18-9-19-13-34(25(16(2)3)24(19)32-10-18)12-17-5-8-23(39-15-17)27(28,29)30/h6-7,9-11,16-17,22-23,25,35H,4-5,8,12-15H2,1-3H3,(H,33,36)/t17-,22+,23-,25+/m1/s1
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<100n/an/an/an/an/an/an/an/a



Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351613
PNG
(US9796710, Compound 7)
Show SMILES CCS(=O)(=O)c1ccc(cc1)C(C)(CO)NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C30H40F3N3O4S/c1-5-41(39,40)25-12-10-23(11-13-25)29(4,18-37)35-28(38)21-14-22-17-36(27(19(2)3)26(22)34-15-21)16-20-6-8-24(9-7-20)30(31,32)33/h10-15,19-20,24,27,37H,5-9,16-18H2,1-4H3,(H,35,38)/t20-,24-,27-,29?/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351743
PNG
(US9796710, Compound 36)
Show SMILES CCS(=O)(=O)c1ccc(nc1)[C@@H](CO)NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C28H37F3N4O4S/c1-4-40(38,39)22-9-10-23(32-13-22)24(16-36)34-27(37)19-11-20-15-35(26(17(2)3)25(20)33-12-19)14-18-5-7-21(8-6-18)28(29,30)31/h9-13,17-18,21,24,26,36H,4-8,14-16H2,1-3H3,(H,34,37)/t18-,21+,24-,26+/m1/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351695
PNG
(US9796710, Compound 25)
Show SMILES CC(C)[C@@H]1N(C[C@H]2CC[C@@H](CO2)C(F)(F)F)Cc2cc(cnc12)C(=O)N[C@@H](CO)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C27H34F3N3O5S/c1-16(2)25-24-19(12-33(25)13-21-7-6-20(15-38-21)27(28,29)30)10-18(11-31-24)26(35)32-23(14-34)17-4-8-22(9-5-17)39(3,36)37/h4-5,8-11,16,20-21,23,25,34H,6-7,12-15H2,1-3H3,(H,32,35)/t20-,21+,23-,25-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351635
PNG
(US9796710, Compound 14)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@H](C(C)C)N(C[C@@H]3CC[C@H](CO3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C28H36F3N3O5S/c1-4-40(37,38)23-9-5-18(6-10-23)24(15-35)33-27(36)19-11-20-13-34(26(17(2)3)25(20)32-12-19)14-22-8-7-21(16-39-22)28(29,30)31/h5-6,9-12,17,21-22,24,26,35H,4,7-8,13-16H2,1-3H3,(H,33,36)/t21-,22+,24+,26+/m1/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351734
PNG
(US9796710, Compound 29 | US9796710, Compound 30 | ...)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@@H](NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1)[C@@H](C)O
Show InChI InChI=1S/C30H40F3N3O4S/c1-5-41(39,40)25-12-8-21(9-13-25)26(19(4)37)35-29(38)22-14-23-17-36(28(18(2)3)27(23)34-15-22)16-20-6-10-24(11-7-20)30(31,32)33/h8-9,12-15,18-20,24,26,28,37H,5-7,10-11,16-17H2,1-4H3,(H,35,38)/t19-,20-,24-,26+,28+/m1/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351642
PNG
(US9796710, Compound 18)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@H](C(C)C)N(C[C@@H]3CC[C@@H](CO3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C28H36F3N3O5S/c1-4-40(37,38)23-9-5-18(6-10-23)24(15-35)33-27(36)19-11-20-13-34(26(17(2)3)25(20)32-12-19)14-22-8-7-21(16-39-22)28(29,30)31/h5-6,9-12,17,21-22,24,26,35H,4,7-8,13-16H2,1-3H3,(H,33,36)/t21-,22-,24-,26-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351638
PNG
(US9796710, Compound 15)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@@H](CO3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C28H36F3N3O5S/c1-4-40(37,38)23-9-5-18(6-10-23)24(15-35)33-27(36)19-11-20-13-34(26(17(2)3)25(20)32-12-19)14-22-8-7-21(16-39-22)28(29,30)31/h5-6,9-12,17,21-22,24,26,35H,4,7-8,13-16H2,1-3H3,(H,33,36)/t21-,22+,24-,26-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351616
PNG
(US9796710, Compound 8)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C29H38F3N3O4S/c1-4-40(38,39)24-11-7-20(8-12-24)25(17-36)34-28(37)21-13-22-16-35(27(18(2)3)26(22)33-14-21)15-19-5-9-23(10-6-19)29(30,31)32/h7-8,11-14,18-19,23,25,27,36H,4-6,9-10,15-17H2,1-3H3,(H,34,37)/t19-,23+,25-,27-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351754
PNG
(US9796710, Compound 47)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@@H](CO)NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C29H38F3N3O4S/c1-4-40(38,39)24-11-7-20(8-12-24)25(17-36)34-28(37)21-13-22-16-35(27(18(2)3)26(22)33-14-21)15-19-5-9-23(10-6-19)29(30,31)32/h7-8,11-14,18-19,23,25,27,36H,4-6,9-10,15-17H2,1-3H3,(H,34,37)/t19-,23-,25-,27+/m1/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351751
PNG
(US9796710, Compound 44)
Show SMILES CCS(=O)(=O)c1ccc(nc1)[C@@H](CO)NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C28H37F3N4O4S/c1-4-40(38,39)22-9-10-23(32-13-22)24(16-36)34-27(37)19-11-20-15-35(26(17(2)3)25(20)33-12-19)14-18-5-7-21(8-6-18)28(29,30)31/h9-13,17-18,21,24,26,36H,4-8,14-16H2,1-3H3,(H,34,37)/t18-,21-,24-,26+/m1/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351746
PNG
(US9796710, Compound 39)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1)[C@H](C)O
Show InChI InChI=1S/C30H40F3N3O4S/c1-5-41(39,40)25-12-8-21(9-13-25)26(19(4)37)35-29(38)22-14-23-17-36(28(18(2)3)27(23)34-15-22)16-20-6-10-24(11-7-20)30(31,32)33/h8-9,12-15,18-20,24,26,28,37H,5-7,10-11,16-17H2,1-4H3,(H,35,38)/t19-,20-,24-,26+,28-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351740
PNG
(US9796710, Compound 33)
Show SMILES CC[C@@H]1N(C[C@H]2CC[C@@H](CC2)C(F)(F)F)Cc2cc(cnc12)C(=O)N[C@@H](CO)c1ccc(cn1)S(=O)(=O)CC
Show InChI InChI=1S/C27H35F3N4O4S/c1-3-24-25-19(15-34(24)14-17-5-7-20(8-6-17)27(28,29)30)11-18(12-32-25)26(36)33-23(16-35)22-10-9-21(13-31-22)39(37,38)4-2/h9-13,17,20,23-24,35H,3-8,14-16H2,1-2H3,(H,33,36)/t17-,20-,23-,24-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351736
PNG
(US9796710, Compound 31)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@H](C3CCOCC3)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C31H40F3N3O5S/c1-2-43(40,41)26-9-5-21(6-10-26)27(19-38)36-30(39)23-15-24-18-37(17-20-3-7-25(8-4-20)31(32,33)34)29(28(24)35-16-23)22-11-13-42-14-12-22/h5-6,9-10,15-16,20,22,25,27,29,38H,2-4,7-8,11-14,17-19H2,1H3,(H,36,39)/t20-,25-,27-,29-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351594
PNG
(US9796710, Compound 4 | US9796710, Compound 5)
Show SMILES CCS(=O)(=O)c1ccc(nc1)[C@H](CO)NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@@H](OC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C27H35F3N4O5S/c1-4-40(37,38)20-6-7-21(31-11-20)22(14-35)33-26(36)18-9-19-13-34(25(16(2)3)24(19)32-10-18)12-17-5-8-23(39-15-17)27(28,29)30/h6-7,9-11,16-17,22-23,25,35H,4-5,8,12-15H2,1-3H3,(H,33,36)/t17-,22+,23-,25+/m1/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351624
PNG
(US9796710, Compound 10)
Show SMILES CC[C@@H]1N(C[C@H]2CC[C@@H](OC2)C(F)(F)F)Cc2cc(cnc12)C(=O)N[C@@H](CO)c1ccc(cc1)S(=O)(=O)CC
Show InChI InChI=1S/C27H34F3N3O5S/c1-3-23-25-20(14-33(23)13-17-5-10-24(38-16-17)27(28,29)30)11-19(12-31-25)26(35)32-22(15-34)18-6-8-21(9-7-18)39(36,37)4-2/h6-9,11-12,17,22-24,34H,3-5,10,13-16H2,1-2H3,(H,32,35)/t17-,22+,23+,24-/m1/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351630
PNG
(US9796710, Compound 13)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@H](COC)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C28H36F3N3O5S/c1-3-40(37,38)23-10-6-19(7-11-23)24(16-35)33-27(36)20-12-21-15-34(25(17-39-2)26(21)32-13-20)14-18-4-8-22(9-5-18)28(29,30)31/h6-7,10-13,18,22,24-25,35H,3-5,8-9,14-17H2,1-2H3,(H,33,36)/t18-,22-,24-,25-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351643
PNG
(US9796710, Compound 19)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@@H](Cc3ccccc3)N(CC(F)(F)F)Cc2c1
Show InChI InChI=1S/C27H28F3N3O4S/c1-2-38(36,37)22-10-8-19(9-11-22)23(16-34)32-26(35)20-13-21-15-33(17-27(28,29)30)24(25(21)31-14-20)12-18-6-4-3-5-7-18/h3-11,13-14,23-24,34H,2,12,15-17H2,1H3,(H,32,35)/t23-,24+/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351651
PNG
(US9796710, Compound 21)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@H](CO3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C28H36F3N3O5S/c1-4-40(37,38)23-9-5-18(6-10-23)24(15-35)33-27(36)19-11-20-13-34(26(17(2)3)25(20)32-12-19)14-22-8-7-21(16-39-22)28(29,30)31/h5-6,9-12,17,21-22,24,26,35H,4,7-8,13-16H2,1-3H3,(H,33,36)/t21-,22-,24+,26+/m1/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351692
PNG
(US9796710, Compound 24)
Show SMILES CC[C@@H]1N(C[C@H]2CC[C@@H](CC2)C(F)(F)F)Cc2cc(cnc12)C(=O)N[C@@H](CO)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C27H34F3N3O4S/c1-3-24-25-20(15-33(24)14-17-4-8-21(9-5-17)27(28,29)30)12-19(13-31-25)26(35)32-23(16-34)18-6-10-22(11-7-18)38(2,36)37/h6-7,10-13,17,21,23-24,34H,3-5,8-9,14-16H2,1-2H3,(H,32,35)/t17-,21-,23-,24-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351706
PNG
(US9796710, Compound 27)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@H](CC3CCOCC3)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C32H42F3N3O5S/c1-2-44(41,42)27-9-5-23(6-10-27)28(20-39)37-31(40)24-16-25-19-38(18-22-3-7-26(8-4-22)32(33,34)35)29(30(25)36-17-24)15-21-11-13-43-14-12-21/h5-6,9-10,16-17,21-22,26,28-29,39H,2-4,7-8,11-15,18-20H2,1H3,(H,37,40)/t22-,26-,28-,29-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351750
PNG
(US9796710, Compound 43)
Show SMILES CCO[C@H]1CC[C@H](CN2Cc3cc(cnc3[C@@H]2C(C)C)C(=O)N[C@@H](CO)c2ccc(cc2)S(=O)(=O)CC)CC1
Show InChI InChI=1S/C30H43N3O5S/c1-5-38-25-11-7-21(8-12-25)17-33-18-24-15-23(16-31-28(24)29(33)20(3)4)30(35)32-27(19-34)22-9-13-26(14-10-22)39(36,37)6-2/h9-10,13-16,20-21,25,27,29,34H,5-8,11-12,17-19H2,1-4H3,(H,32,35)/t21-,25-,27-,29-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351753
PNG
((S)—N—((R)-1-(4-(ethylsulfonyl)phenyl-2-...)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C29H38F3N3O4S/c1-4-40(38,39)24-11-7-20(8-12-24)25(17-36)34-28(37)21-13-22-16-35(27(18(2)3)26(22)33-14-21)15-19-5-9-23(10-6-19)29(30,31)32/h7-8,11-14,18-19,23,25,27,36H,4-6,9-10,15-17H2,1-3H3,(H,34,37)/t19-,23-,25-,27-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351628
PNG
(US9796710, Compound 11)
Show SMILES CC[C@@H]1N(C[C@@H]2CC[C@H](OC2)C(F)(F)F)Cc2cc(cnc12)C(=O)N[C@@H](CO)c1ccc(cc1)S(=O)(=O)CC
Show InChI InChI=1S/C27H34F3N3O5S/c1-3-23-25-20(14-33(23)13-17-5-10-24(38-16-17)27(28,29)30)11-19(12-31-25)26(35)32-22(15-34)18-6-8-21(9-7-18)39(36,37)4-2/h6-9,11-12,17,22-24,34H,3-5,10,13-16H2,1-2H3,(H,32,35)/t17-,22-,23-,24-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351687
PNG
(US9796710, Compound 22)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@H](Cc3ccccc3)N(CC(F)(F)F)Cc2c1
Show InChI InChI=1S/C27H28F3N3O4S/c1-2-38(36,37)22-10-8-19(9-11-22)23(16-34)32-26(35)20-13-21-15-33(17-27(28,29)30)24(25(21)31-14-20)12-18-6-4-3-5-7-18/h3-11,13-14,23-24,34H,2,12,15-17H2,1H3,(H,32,35)/t23-,24-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351705
PNG
(US9796710, Compound 26)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@H](C)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C27H34F3N3O4S/c1-3-38(36,37)23-10-6-19(7-11-23)24(16-34)32-26(35)20-12-21-15-33(17(2)25(21)31-13-20)14-18-4-8-22(9-5-18)27(28,29)30/h6-7,10-13,17-18,22,24,34H,3-5,8-9,14-16H2,1-2H3,(H,32,35)/t17-,18-,22-,24-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351752
PNG
(US9796710, Compound 45)
Show SMILES CCS(=O)(=O)c1ccc(nc1)[C@H](CO)NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C28H37F3N4O4S/c1-4-40(38,39)22-9-10-23(32-13-22)24(16-36)34-27(37)19-11-20-15-35(26(17(2)3)25(20)33-12-19)14-18-5-7-21(8-6-18)28(29,30)31/h9-13,17-18,21,24,26,36H,4-8,14-16H2,1-3H3,(H,34,37)/t18-,21-,24-,26-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351559
PNG
(US9796710, Compound 1)
Show SMILES CCS(=O)(=O)c1ccc(nc1)[C@H](CO)NC(=O)c1cnc2[C@H](C(C)C)N(C[C@@H]3CC[C@H](OC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C27H35F3N4O5S/c1-4-40(37,38)20-6-7-21(31-11-20)22(14-35)33-26(36)18-9-19-13-34(25(16(2)3)24(19)32-10-18)12-17-5-8-23(39-15-17)27(28,29)30/h6-7,9-11,16-17,22-23,25,35H,4-5,8,12-15H2,1-3H3,(H,33,36)/t17-,22-,23-,25-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351562
PNG
(US9796710, Compound 2)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@H](C(C)C)N(C[C@@H]3CC[C@H](OC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C28H36F3N3O5S/c1-4-40(37,38)22-8-6-19(7-9-22)23(15-35)33-27(36)20-11-21-14-34(26(17(2)3)25(21)32-12-20)13-18-5-10-24(39-16-18)28(29,30)31/h6-9,11-12,17-18,23-24,26,35H,4-5,10,13-16H2,1-3H3,(H,33,36)/t18-,23-,24-,26-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351690
PNG
(US9796710, Compound 23)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2C(N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1)C(F)(F)F
Show InChI InChI=1S/C27H31F6N3O4S/c1-2-41(39,40)21-9-5-17(6-10-21)22(15-37)35-25(38)18-11-19-14-36(24(27(31,32)33)23(19)34-12-18)13-16-3-7-20(8-4-16)26(28,29)30/h5-6,9-12,16,20,22,24,37H,2-4,7-8,13-15H2,1H3,(H,35,38)/t16-,20-,22-,24?/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351748
PNG
((S)-7-ethyl-N—((R)-1-(4-(ethylsulfonyl)phenyl...)
Show SMILES CC[C@@H]1N(C[C@H]2CC[C@@H](CC2)C(F)(F)F)Cc2cc(cnc12)C(=O)N[C@@H](CO)c1ccc(cc1)S(=O)(=O)CC
Show InChI InChI=1S/C28H36F3N3O4S/c1-3-25-26-21(16-34(25)15-18-5-9-22(10-6-18)28(29,30)31)13-20(14-32-26)27(36)33-24(17-35)19-7-11-23(12-8-19)39(37,38)4-2/h7-8,11-14,18,22,24-25,35H,3-6,9-10,15-17H2,1-2H3,(H,33,36)/t18-,22-,24-,25-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351564
PNG
(US9796710, Compound 3)
Show SMILES CC[C@@H]1N(C[C@H]2CC[C@H](OC2)C(F)(F)F)Cc2cc(cnc12)C(=O)N[C@@H](CO)c1ccc(cn1)S(=O)(=O)CC
Show InChI InChI=1S/C26H33F3N4O5S/c1-3-22-24-18(13-33(22)12-16-5-8-23(38-15-16)26(27,28)29)9-17(10-31-24)25(35)32-21(14-34)20-7-6-19(11-30-20)39(36,37)4-2/h6-7,9-11,16,21-23,34H,3-5,8,12-15H2,1-2H3,(H,32,35)/t16-,21+,22+,23+/m1/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351744
PNG
(US9796710, Compound 37)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@H](Cc3ccccc3)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C33H38F3N3O4S/c1-2-44(42,43)28-14-10-24(11-15-28)29(21-40)38-32(41)25-17-26-20-39(19-23-8-12-27(13-9-23)33(34,35)36)30(31(26)37-18-25)16-22-6-4-3-5-7-22/h3-7,10-11,14-15,17-18,23,27,29-30,40H,2,8-9,12-13,16,19-21H2,1H3,(H,38,41)/t23-,27-,29-,30-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351644
PNG
(US9796710, Compound 20)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@H](CO)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C27H34F3N3O5S/c1-2-39(37,38)22-9-5-18(6-10-22)23(15-34)32-26(36)19-11-20-14-33(24(16-35)25(20)31-12-19)13-17-3-7-21(8-4-17)27(28,29)30/h5-6,9-12,17,21,23-24,34-35H,2-4,7-8,13-16H2,1H3,(H,32,36)/t17-,21-,23-,24-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351629
PNG
(US9796710, Compound 12)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@@H](COC)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C28H36F3N3O5S/c1-3-40(37,38)23-10-6-19(7-11-23)24(16-35)33-27(36)20-12-21-15-34(25(17-39-2)26(21)32-13-20)14-18-4-8-22(9-5-18)28(29,30)31/h6-7,10-13,18,22,24-25,35H,3-5,8-9,14-17H2,1-2H3,(H,33,36)/t18-,22-,24-,25+/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351734
PNG
(US9796710, Compound 29 | US9796710, Compound 30 | ...)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@@H](NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1)[C@@H](C)O
Show InChI InChI=1S/C30H40F3N3O4S/c1-5-41(39,40)25-12-8-21(9-13-25)26(19(4)37)35-29(38)22-14-23-17-36(28(18(2)3)27(23)34-15-22)16-20-6-10-24(11-7-20)30(31,32)33/h8-9,12-15,18-20,24,26,28,37H,5-7,10-11,16-17H2,1-4H3,(H,35,38)/t19-,20-,24-,26+,28+/m1/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351619
PNG
(US9796710, Compound 9)
Show SMILES CCS(=O)(=O)c1ccc(cc1)C(C)(CO)NC(=O)c1cnc2[C@@H](C(C)C)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C30H40F3N3O4S/c1-5-41(39,40)25-12-10-23(11-13-25)29(4,18-37)35-28(38)21-14-22-17-36(27(19(2)3)26(22)34-15-21)16-20-6-8-24(9-7-20)30(31,32)33/h10-15,19-20,24,27,37H,5-9,16-18H2,1-4H3,(H,35,38)/t20-,24-,27-,29?/m1/s1
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550n/an/an/an/an/an/an/an/a



Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351745
PNG
(US9796710, Compound 38)
Show SMILES CC[C@H]1N(C[C@H]2CC[C@@H](CC2)C(F)(F)F)Cc2cc(cnc12)C(=O)N[C@@H](CO)c1ccc(cc1)S(=O)(=O)CC
Show InChI InChI=1S/C28H36F3N3O4S/c1-3-25-26-21(16-34(25)15-18-5-9-22(10-6-18)28(29,30)31)13-20(14-32-26)27(36)33-24(17-35)19-7-11-23(12-8-19)39(37,38)4-2/h7-8,11-14,18,22,24-25,35H,3-6,9-10,15-17H2,1-2H3,(H,33,36)/t18-,22-,24-,25+/m0/s1
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550n/an/an/an/an/an/an/an/a



Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351640
PNG
(US9796710, Compound 16)
Show SMILES CC[C@@H]1N(C[C@H]2CC[C@@H](CC2)C(F)(F)F)Cc2cc(cnc12)C(=O)N[C@@H](CO)c1ccc(cn1)S(C)(=O)=O
Show InChI InChI=1S/C26H33F3N4O4S/c1-3-23-24-18(14-33(23)13-16-4-6-19(7-5-16)26(27,28)29)10-17(11-31-24)25(35)32-22(15-34)21-9-8-20(12-30-21)38(2,36)37/h8-12,16,19,22-23,34H,3-7,13-15H2,1-2H3,(H,32,35)/t16-,19-,22-,23-/m0/s1
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550n/an/an/an/an/an/an/an/a



Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351742
PNG
(US9796710, Compound 35)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@H](Cc3ccccc3)N(C)Cc2c1
Show InChI InChI=1S/C26H29N3O4S/c1-3-34(32,33)22-11-9-19(10-12-22)23(17-30)28-26(31)20-14-21-16-29(2)24(25(21)27-15-20)13-18-7-5-4-6-8-18/h4-12,14-15,23-24,30H,3,13,16-17H2,1-2H3,(H,28,31)/t23-,24-/m0/s1
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550n/an/an/an/an/an/an/an/a



Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351741
PNG
(US9796710, Compound 34)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@@H](Cc3ccccc3)N(C)Cc2c1
Show InChI InChI=1S/C26H29N3O4S/c1-3-34(32,33)22-11-9-19(10-12-22)23(17-30)28-26(31)20-14-21-16-29(2)24(25(21)27-15-20)13-18-7-5-4-6-8-18/h4-12,14-15,23-24,30H,3,13,16-17H2,1-2H3,(H,28,31)/t23-,24+/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351739
PNG
(US9796710, Compound 32)
Show SMILES CC[C@H]1N(C[C@H]2CC[C@@H](CC2)C(F)(F)F)Cc2cc(cnc12)C(=O)N[C@@H](CO)c1ccc(cn1)S(=O)(=O)CC
Show InChI InChI=1S/C27H35F3N4O4S/c1-3-24-25-19(15-34(24)14-17-5-7-20(8-6-17)27(28,29)30)11-18(12-32-25)26(36)33-23(16-35)22-10-9-21(13-31-22)39(37,38)4-2/h9-13,17,20,23-24,35H,3-8,14-16H2,1-2H3,(H,33,36)/t17-,20-,23-,24+/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351734
PNG
(US9796710, Compound 29 | US9796710, Compound 30 | ...)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@@H](NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1)[C@@H](C)O
Show InChI InChI=1S/C30H40F3N3O4S/c1-5-41(39,40)25-12-8-21(9-13-25)26(19(4)37)35-29(38)22-14-23-17-36(28(18(2)3)27(23)34-15-22)16-20-6-10-24(11-7-20)30(31,32)33/h8-9,12-15,18-20,24,26,28,37H,5-7,10-11,16-17H2,1-4H3,(H,35,38)/t19-,20-,24-,26+,28+/m1/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351604
PNG
(US9796710, Compound 6)
Show SMILES CC[C@@H]1N(C[C@@H]2CC[C@H](OC2)C(F)(F)F)Cc2cc(cnc12)C(=O)N[C@@H](CO)c1ccc(cn1)S(=O)(=O)CC
Show InChI InChI=1S/C26H33F3N4O5S/c1-3-22-24-18(13-33(22)12-16-5-8-23(38-15-16)26(27,28)29)9-17(10-31-24)25(35)32-21(14-34)20-7-6-19(11-30-20)39(36,37)4-2/h6-7,9-11,16,21-23,34H,3-5,8,12-15H2,1-2H3,(H,32,35)/t16-,21-,22-,23-/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351747
PNG
(US9796710, Compound 40)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@@H](Cc3ccccc3)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C33H38F3N3O4S/c1-2-44(42,43)28-14-10-24(11-15-28)29(21-40)38-32(41)25-17-26-20-39(19-23-8-12-27(13-9-23)33(34,35)36)30(31(26)37-18-25)16-22-6-4-3-5-7-22/h3-7,10-11,14-15,17-18,23,27,29-30,40H,2,8-9,12-13,16,19-21H2,1H3,(H,38,41)/t23-,27-,29-,30+/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351733
PNG
(US9796710, Compound 28)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@@H](C)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C27H34F3N3O4S/c1-3-38(36,37)23-10-6-19(7-11-23)24(16-34)32-26(35)20-12-21-15-33(17(2)25(21)31-13-20)14-18-4-8-22(9-5-18)27(28,29)30/h6-7,10-13,17-18,22,24,34H,3-5,8-9,14-16H2,1-2H3,(H,32,35)/t17-,18-,22-,24+/m1/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM351641
PNG
(US9796710, Compound 17)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2[C@@H](CO)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C27H34F3N3O5S/c1-2-39(37,38)22-9-5-18(6-10-22)23(15-34)32-26(36)19-11-20-14-33(24(16-35)25(20)31-12-19)13-17-3-7-21(8-4-17)27(28,29)30/h5-6,9-12,17,21,23-24,34-35H,2-4,7-8,13-16H2,1H3,(H,32,36)/t17-,21-,23-,24+/m0/s1
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Vitae Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds of the present invention were tested for ability to bind to ROR in a cell-free competition assay with commercially available radio-ligand (...


US Patent US9796710 (2017)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%