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Patent code US9796732

Compile Data Set for Download or QSAR
Found 42 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351917
PNG
(Preparation of 5-(2,4-di(3-oxa-8-azabicyclo[3.2.1]...)
Show SMILES COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1C2CCC1COC2)N1C2CCC1COC2
Show InChI InChI=1S/C27H31N5O4/c1-34-24-9-2-16(10-17(24)11-33)23-8-7-22-25(28-23)29-27(32-20-5-6-21(32)15-36-14-20)30-26(22)31-18-3-4-19(31)13-35-12-18/h2,7-10,18-21,33H,3-6,11-15H2,1H3
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n/an/a 1n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351935
PNG
(Preparation of 5-(2-((1R,5S)-3-oxa-8-azabicyclo[3....)
Show SMILES COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1C2CCC1COC2)N1CCOC[C@@H]1C
Show InChI InChI=1S/C26H31N5O4/c1-16-13-34-10-9-30(16)25-21-6-7-22(17-3-8-23(33-2)18(11-17)12-32)27-24(21)28-26(29-25)31-19-4-5-20(31)15-35-14-19/h3,6-8,11,16,19-20,32H,4-5,9-10,12-15H2,1-2H3/t16-,19?,20?/m0/s1
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n/an/a 2n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351927
PNG
(Preparation of 5-(4-(3-oxa-8-azabicyclo[3.2.1]octa...)
Show SMILES COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1CCOC[C@@H]1C)N1C2CCC1COC2
Show InChI InChI=1S/C26H31N5O4/c1-16-13-34-10-9-30(16)26-28-24-21(25(29-26)31-19-4-5-20(31)15-35-14-19)6-7-22(27-24)17-3-8-23(33-2)18(11-17)12-32/h3,6-8,11,16,19-20,32H,4-5,9-10,12-15H2,1-2H3/t16-,19?,20?/m0/s1
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n/an/a 3n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351923
PNG
(Preparation of 5-(2,4-di(8-oxa-3-azabicyclo[3.2.1]...)
Show SMILES COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1CC2CCC(C1)O2)N1CC2CCC(C1)O2
Show InChI InChI=1S/C27H31N5O4/c1-34-24-9-2-16(10-17(24)15-33)23-8-7-22-25(28-23)29-27(32-13-20-5-6-21(14-32)36-20)30-26(22)31-11-18-3-4-19(12-31)35-18/h2,7-10,18-21,33H,3-6,11-15H2,1H3
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n/an/a 3n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351931
PNG
(Preparation of 5-(2-(8-oxa-3-azabicyclo[3.2.1]octa...)
Show SMILES COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1CC2CCC(C1)O2)N1C2CCC1COC2
Show InChI InChI=1S/C27H31N5O4/c1-34-24-9-2-16(10-17(24)13-33)23-8-7-22-25(28-23)29-27(31-11-20-5-6-21(12-31)36-20)30-26(22)32-18-3-4-19(32)15-35-14-18/h2,7-10,18-21,33H,3-6,11-15H2,1H3
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n/an/a 4n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351929
PNG
(Preparation of 5-(4-(3-oxa-8-azabicyclo[3.2.1]octa...)
Show SMILES COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1C[C@H](C)O[C@H](C)C1)N1C2CCC1COC2
Show InChI InChI=1S/C27H33N5O4/c1-16-11-31(12-17(2)36-16)27-29-25-22(26(30-27)32-20-5-6-21(32)15-35-14-20)7-8-23(28-25)18-4-9-24(34-3)19(10-18)13-33/h4,7-10,16-17,20-21,33H,5-6,11-15H2,1-3H3/t16-,17+,20?,21?
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n/an/a 5n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351928
PNG
(Preparation of 5-(4-(3-oxa-8-azabicyclo[3.2.1]octa...)
Show SMILES COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1CCOCC1)N1C2CCC1COC2
Show InChI InChI=1S/C25H29N5O4/c1-32-22-7-2-16(12-17(22)13-31)21-6-5-20-23(26-21)27-25(29-8-10-33-11-9-29)28-24(20)30-18-3-4-19(30)15-34-14-18/h2,5-7,12,18-19,31H,3-4,8-11,13-15H2,1H3
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n/an/a 5n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351939
PNG
(Preparation of 5-(4-(8-oxa-3-azabicyclo[3.2.1]octa...)
Show SMILES COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1C2CCC1COC2)N1CC2CCC(C1)O2
Show InChI InChI=1S/C27H31N5O4/c1-34-24-9-2-16(10-17(24)13-33)23-8-7-22-25(28-23)29-27(32-18-3-4-19(32)15-35-14-18)30-26(22)31-11-20-5-6-21(12-31)36-20/h2,7-10,18-21,33H,3-6,11-15H2,1H3
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n/an/a 9n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351936
PNG
(Preparation of 5-(2-((1R,5S)-3-oxa-8-azabicyclo[3....)
Show SMILES COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1C2CCC1COC2)N1CCOCC1
Show InChI InChI=1S/C25H29N5O4/c1-32-22-7-2-16(12-17(22)13-31)21-6-5-20-23(26-21)27-25(28-24(20)29-8-10-33-11-9-29)30-18-3-4-19(30)15-34-14-18/h2,5-7,12,18-19,31H,3-4,8-11,13-15H2,1H3
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n/an/a 11n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351949
PNG
(Preparation of (5-(2,4-di((S)-3-methylmorpholinyl)...)
Show SMILES COc1ccc(cc1CO)-c1cc2nc(nc(N3CCOC[C@@H]3C)c2cn1)N1CCOC[C@@H]1C
Show InChI InChI=1S/C25H31N5O4/c1-16-14-33-8-6-29(16)24-20-12-26-21(18-4-5-23(32-3)19(10-18)13-31)11-22(20)27-25(28-24)30-7-9-34-15-17(30)2/h4-5,10-12,16-17,31H,6-9,13-15H2,1-3H3/t16-,17-/m0/s1
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n/an/a 12n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351958
PNG
(Preparation of (5-(4-((1R,5S)-3-oxa-8-azabicyclo[3...)
Show SMILES COc1ccc(cc1CO)-c1cc2nc(nc(N3C4CCC3COC4)c2cn1)N1CCOC[C@@H]1C
Show InChI InChI=1S/C26H31N5O4/c1-16-13-34-8-7-30(16)26-28-23-10-22(17-3-6-24(33-2)18(9-17)12-32)27-11-21(23)25(29-26)31-19-4-5-20(31)15-35-14-19/h3,6,9-11,16,19-20,32H,4-5,7-8,12-15H2,1-2H3/t16-,19?,20?/m0/s1
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n/an/a 18n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351973
PNG
(Preparation of 3-(2-(3-oxa-8-azabicyclo[3.2.1]octa...)
Show SMILES CNC(=O)c1cccc(c1)-c1ccc2c(nc(nc2n1)N1C2CCC1COC2)N1CCOC[C@@H]1C
Show InChI InChI=1S/C26H30N6O3/c1-16-13-34-11-10-31(16)24-21-8-9-22(17-4-3-5-18(12-17)25(33)27-2)28-23(21)29-26(30-24)32-19-6-7-20(32)15-35-14-19/h3-5,8-9,12,16,19-20H,6-7,10-11,13-15H2,1-2H3,(H,27,33)/t16-,19?,20?/m0/s1
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n/an/a 21n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351930
PNG
(Preparation of 5-(4-(3-oxa-8-azabicyclo[3.2.1]octa...)
Show SMILES COCCN(C)c1nc(N2C3CCC2COC3)c2ccc(nc2n1)-c1ccc(OC)c(CO)c1
Show InChI InChI=1S/C25H31N5O4/c1-29(10-11-32-2)25-27-23-20(24(28-25)30-18-5-6-19(30)15-34-14-18)7-8-21(26-23)16-4-9-22(33-3)17(12-16)13-31/h4,7-9,12,18-19,31H,5-6,10-11,13-15H2,1-3H3
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n/an/a 22n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351974
PNG
(Preparation of 3-(2-(8-oxa-3-azabicyclo[3.2.1]octa...)
Show SMILES CNC(=O)c1cccc(c1)-c1ccc2c(nc(nc2n1)N1CC2CCC(C1)O2)N1CCOC[C@@H]1C
Show InChI InChI=1S/C26H30N6O3/c1-16-15-34-11-10-32(16)24-21-8-9-22(17-4-3-5-18(12-17)25(33)27-2)28-23(21)29-26(30-24)31-13-19-6-7-20(14-31)35-19/h3-5,8-9,12,16,19-20H,6-7,10-11,13-15H2,1-2H3,(H,27,33)/t16-,19?,20?/m0/s1
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n/an/a 32n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351956
PNG
(Preparation of (5-(2,4-di(3-oxa-8-azabicyclo[3.2.1...)
Show SMILES COc1ccc(cc1CO)-c1cc2nc(nc(N3C4CCC3COC4)c2cn1)N1C2CCC1COC2
Show InChI InChI=1S/C27H31N5O4/c1-34-25-7-2-16(8-17(25)11-33)23-9-24-22(10-28-23)26(31-18-3-4-19(31)13-35-12-18)30-27(29-24)32-20-5-6-21(32)15-36-14-20/h2,7-10,18-21,33H,3-6,11-15H2,1H3
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n/an/a 35n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351957
PNG
(Preparation of (5-(4-(1R,5S)-3-oxa-8-azabicyclo[3....)
Show SMILES COc1ccc(cc1CO)-c1cc2nc(nc(N3C4CCC3COC4)c2cn1)N1CCOCC1
Show InChI InChI=1S/C25H29N5O4/c1-32-23-5-2-16(10-17(23)13-31)21-11-22-20(12-26-21)24(30-18-3-4-19(30)15-34-14-18)28-25(27-22)29-6-8-33-9-7-29/h2,5,10-12,18-19,31H,3-4,6-9,13-15H2,1H3
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n/an/a 35n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351976
PNG
(Preparation of 3-(4-(3-oxa-8-azabicyclo[3.2.1]octa...)
Show SMILES CNC(=O)c1cccc(c1)-c1ccc2c(nc(nc2n1)N1CCOC[C@@H]1C)N1C2CCC1COC2
Show InChI InChI=1S/C26H30N6O3/c1-16-13-34-11-10-31(16)26-29-23-21(24(30-26)32-19-6-7-20(32)15-35-14-19)8-9-22(28-23)17-4-3-5-18(12-17)25(33)27-2/h3-5,8-9,12,16,19-20H,6-7,10-11,13-15H2,1-2H3,(H,27,33)/t16-,19?,20?/m0/s1
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n/an/a 39n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351942
PNG
(Preparation of 5-(2-((1R,5S)-3-oxa-8-azabicyclo[3....)
Show SMILES COCCN(C)c1nc(nc2nc(ccc12)-c1ccc(OC)c(CO)c1)N1C2CCC1COC2
Show InChI InChI=1S/C25H31N5O4/c1-29(10-11-32-2)24-20-7-8-21(16-4-9-22(33-3)17(12-16)13-31)26-23(20)27-25(28-24)30-18-5-6-19(30)15-34-14-18/h4,7-9,12,18-19,31H,5-6,10-11,13-15H2,1-3H3
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n/an/a 57n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351964
PNG
(Preparation of (3S,3′S)-4,4′-(7-phenyl...)
Show SMILES C[C@H]1COCCN1c1nc(N2CCOC[C@@H]2C)c2cnc(cc2n1)-c1ccccc1
Show InChI InChI=1S/C23H27N5O2/c1-16-14-29-10-8-27(16)22-19-13-24-20(18-6-4-3-5-7-18)12-21(19)25-23(26-22)28-9-11-30-15-17(28)2/h3-7,12-13,16-17H,8-11,14-15H2,1-2H3/t16-,17-/m0/s1
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n/an/a 58n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351972
PNG
(Preparation of 3-(2,4-di(3-oxa-8-azabicyclo[3.2.1]...)
Show SMILES CNC(=O)c1cccc(c1)-c1ccc2c(nc(nc2n1)N1C2CCC1COC2)N1C2CCC1COC2
Show InChI InChI=1S/C27H30N6O3/c1-28-26(34)17-4-2-3-16(11-17)23-10-9-22-24(29-23)30-27(33-20-7-8-21(33)15-36-14-20)31-25(22)32-18-5-6-19(32)13-35-12-18/h2-4,9-11,18-21H,5-8,12-15H2,1H3,(H,28,34)
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n/an/a 60n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351944
PNG
(Preparation of (S)-(2-methoxy-5-(2-(3-methylmorpho...)
Show SMILES COc1ccc(cc1CO)-c1cc2nc(nc(N3CCOCC3)c2cn1)N1CCOC[C@@H]1C
Show InChI InChI=1S/C24H29N5O4/c1-16-15-33-10-7-29(16)24-26-21-12-20(17-3-4-22(31-2)18(11-17)14-30)25-13-19(21)23(27-24)28-5-8-32-9-6-28/h3-4,11-13,16,30H,5-10,14-15H2,1-2H3/t16-/m0/s1
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n/an/a 62n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351979
PNG
(Preparation of 3-(4-(8-oxa-3-azabicyclo[3.2.1]octa...)
Show SMILES CNC(=O)c1cccc(c1)-c1ccc2c(nc(nc2n1)N1CCOC[C@@H]1C)N1CC2CCC(C1)O2
Show InChI InChI=1S/C26H30N6O3/c1-16-15-34-11-10-32(16)26-29-23-21(24(30-26)31-13-19-6-7-20(14-31)35-19)8-9-22(28-23)17-4-3-5-18(12-17)25(33)27-2/h3-5,8-9,12,16,19-20H,6-7,10-11,13-15H2,1-2H3,(H,27,33)/t16-,19?,20?/m0/s1
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n/an/a 64n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351980
PNG
(Preparation of 3-(2-(3-oxa-8-azabicyclo[3.2.1]octa...)
Show SMILES CNC(=O)c1cccc(c1)-c1ccc2c(nc(nc2n1)N1C2CCC1COC2)N1CC2CCC(C1)O2
Show InChI InChI=1S/C27H30N6O3/c1-28-26(34)17-4-2-3-16(11-17)23-10-9-22-24(29-23)30-27(33-18-5-6-19(33)15-35-14-18)31-25(22)32-12-20-7-8-21(13-32)36-20/h2-4,9-11,18-21H,5-8,12-15H2,1H3,(H,28,34)
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n/an/a 71n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351951
PNG
(Preparation of (S)-(2-methoxy-5-(4-(3-methylmorpho...)
Show SMILES COc1ccc(cc1CO)-c1cc2nc(nc(N3CCOC[C@@H]3C)c2cn1)N1CCOCC1
Show InChI InChI=1S/C24H29N5O4/c1-16-15-33-10-7-29(16)23-19-13-25-20(17-3-4-22(31-2)18(11-17)14-30)12-21(19)26-24(27-23)28-5-8-32-9-6-28/h3-4,11-13,16,30H,5-10,14-15H2,1-2H3/t16-/m0/s1
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n/an/a 71n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351955
PNG
(Preparation of (5-(4-(8-oxa-3-azabicyclo[3.2.1]oct...)
Show SMILES COc1ccc(cc1CO)-c1cc2nc(nc(N3CC4CCC(C3)O4)c2cn1)N1CCOC[C@@H]1C
Show InChI InChI=1S/C26H31N5O4/c1-16-15-34-8-7-31(16)26-28-23-10-22(17-3-6-24(33-2)18(9-17)14-32)27-11-21(23)25(29-26)30-12-19-4-5-20(13-30)35-19/h3,6,9-11,16,19-20,32H,4-5,7-8,12-15H2,1-2H3/t16-,19?,20?/m0/s1
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n/an/a 73n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351966
PNG
(Preparation of 3-(4-((S)-3-methylmorpholinyl)-7-ph...)
Show SMILES C[C@H]1COCCN1c1nc(nc2cc(ncc12)-c1ccccc1)N1CC2CCC(C1)O2
Show InChI InChI=1S/C24H27N5O2/c1-16-15-30-10-9-29(16)23-20-12-25-21(17-5-3-2-4-6-17)11-22(20)26-24(27-23)28-13-18-7-8-19(14-28)31-18/h2-6,11-12,16,18-19H,7-10,13-15H2,1H3/t16-,18?,19?/m0/s1
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n/an/a 74n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351952
PNG
(Preparation of (5-(2,4-di(8-oxa-3-azabicyclo[3.2.1...)
Show SMILES COc1ccc(cc1CO)-c1cc2nc(nc(N3CC4CCC(C3)O4)c2cn1)N1CC2CCC(C1)O2
Show InChI InChI=1S/C27H31N5O4/c1-34-25-7-2-16(8-17(25)15-33)23-9-24-22(10-28-23)26(31-11-18-3-4-19(12-31)35-18)30-27(29-24)32-13-20-5-6-21(14-32)36-20/h2,7-10,18-21,33H,3-6,11-15H2,1H3
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n/an/a 80n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351978
PNG
(Preparation of 3-(4-(3-oxa-8-azabicyclo[3.2.1]octa...)
Show SMILES CNC(=O)c1cccc(c1)-c1ccc2c(nc(nc2n1)N1C[C@H](C)O[C@H](C)C1)N1C2CCC1COC2
Show InChI InChI=1S/C27H32N6O3/c1-16-12-32(13-17(2)36-16)27-30-24-22(25(31-27)33-20-7-8-21(33)15-35-14-20)9-10-23(29-24)18-5-4-6-19(11-18)26(34)28-3/h4-6,9-11,16-17,20-21H,7-8,12-15H2,1-3H3,(H,28,34)/t16-,17+,20?,21?
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n/an/a 93n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351960
PNG
(Preparation of (S)-3-methyl-4-(4-morpholinyl-7-phe...)
Show SMILES C[C@H]1COCCN1c1nc(N2CCOCC2)c2cnc(cc2n1)-c1ccccc1
Show InChI InChI=1S/C22H25N5O2/c1-16-15-29-12-9-27(16)22-24-20-13-19(17-5-3-2-4-6-17)23-14-18(20)21(25-22)26-7-10-28-11-8-26/h2-6,13-14,16H,7-12,15H2,1H3/t16-/m0/s1
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n/an/a 134n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351963
PNG
(Preparation of (S)-3-methyl-4-(2-morpholinyl-7-phe...)
Show SMILES C[C@H]1COCCN1c1nc(nc2cc(ncc12)-c1ccccc1)N1CCOCC1
Show InChI InChI=1S/C22H25N5O2/c1-16-15-29-12-9-27(16)21-18-14-23-19(17-5-3-2-4-6-17)13-20(18)24-22(25-21)26-7-10-28-11-8-26/h2-6,13-14,16H,7-12,15H2,1H3/t16-/m0/s1
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n/an/a 153n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351975
PNG
(Preparation of 3-(4-(3-oxa-8-azabicyclo[3.2.1]octa...)
Show SMILES CNC(=O)c1cccc(c1)-c1ccc2c(nc(nc2n1)N1CCOCC1)N1C2CCC1COC2
Show InChI InChI=1S/C25H28N6O3/c1-26-24(32)17-4-2-3-16(13-17)21-8-7-20-22(27-21)28-25(30-9-11-33-12-10-30)29-23(20)31-18-5-6-19(31)15-34-14-18/h2-4,7-8,13,18-19H,5-6,9-12,14-15H2,1H3,(H,26,32)
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n/an/a 166n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351971
PNG
(Preparation of 3,3′-(7-phenylpyrimido[4,5-d]...)
Show SMILES C1CC2CN(CC1O2)c1nc(N2CC3CCC(C2)O3)c2cnc(nc2n1)-c1ccccc1
Show InChI InChI=1S/C24H26N6O2/c1-2-4-15(5-3-1)21-25-10-20-22(26-21)27-24(30-13-18-8-9-19(14-30)32-18)28-23(20)29-11-16-6-7-17(12-29)31-16/h1-5,10,16-19H,6-9,11-14H2
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n/an/a 195n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351953
PNG
(Preparation of (5-(4-(8-oxa-3-azabicyclo[3.2.1]oct...)
Show SMILES COc1ccc(cc1CO)-c1cc2nc(nc(N3CC4CCC(C3)O4)c2cn1)N1CCOCC1
Show InChI InChI=1S/C25H29N5O4/c1-32-23-5-2-16(10-17(23)15-31)21-11-22-20(12-26-21)24(30-13-18-3-4-19(14-30)34-18)28-25(27-22)29-6-8-33-9-7-29/h2,5,10-12,18-19,31H,3-4,6-9,13-15H2,1H3
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n/an/a 205n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351945
PNG
(Preparation of 5-(2-((2S,6R)-2,6-dimethylmorpholin...)
Show SMILES COc1ccc(cc1CO)-c1cc2nc(nc(N3CCOCC3)c2cn1)N1C[C@H](C)O[C@H](C)C1
Show InChI InChI=1S/C25H31N5O4/c1-16-13-30(14-17(2)34-16)25-27-22-11-21(18-4-5-23(32-3)19(10-18)15-31)26-12-20(22)24(28-25)29-6-8-33-9-7-29/h4-5,10-12,16-17,31H,6-9,13-15H2,1-3H3/t16-,17+
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n/an/a 297n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351970
PNG
(Preparation of (3S,3′S)-4,4′-(7-phenyl...)
Show SMILES C[C@H]1COCCN1c1nc(N2CCOC[C@@H]2C)c2cnc(nc2n1)-c1ccccc1
Show InChI InChI=1S/C22H26N6O2/c1-15-13-29-10-8-27(15)21-18-12-23-19(17-6-4-3-5-7-17)24-20(18)25-22(26-21)28-9-11-30-14-16(28)2/h3-7,12,15-16H,8-11,13-14H2,1-2H3/t15-,16-/m0/s1
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n/an/a 413n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351961
PNG
(Preparation of 3-(4-morpholinyl-7-phenylpyrido[4,3...)
Show SMILES C1CC2CN(CC1O2)c1nc(N2CCOCC2)c2cnc(cc2n1)-c1ccccc1
Show InChI InChI=1S/C23H25N5O2/c1-2-4-16(5-3-1)20-12-21-19(13-24-20)22(27-8-10-29-11-9-27)26-23(25-21)28-14-17-6-7-18(15-28)30-17/h1-5,12-13,17-18H,6-11,14-15H2
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n/an/a 435n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351943
PNG
(Preparation of (5-(2,4-dimorpholinylpyrido[4,3-d]p...)
Show SMILES COc1ccc(cc1CO)-c1cc2nc(nc(N3CCOCC3)c2cn1)N1CCOCC1
Show InChI InChI=1S/C23H27N5O4/c1-30-21-3-2-16(12-17(21)15-29)19-13-20-18(14-24-19)22(27-4-8-31-9-5-27)26-23(25-20)28-6-10-32-11-7-28/h2-3,12-14,29H,4-11,15H2,1H3
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n/an/a 451n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351959
PNG
(Preparation of (4,4′-(7-phenylpyrido[4,3-d]p...)
Show SMILES C1CN(CCO1)c1nc(N2CCOCC2)c2cnc(cc2n1)-c1ccccc1
Show InChI InChI=1S/C21H23N5O2/c1-2-4-16(5-3-1)18-14-19-17(15-22-18)20(25-6-10-27-11-7-25)24-21(23-19)26-8-12-28-13-9-26/h1-5,14-15H,6-13H2
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n/an/a 464n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351946
PNG
(Preparation of 5-(4-((2S,6R)-2,6-dimethyl morpholi...)
Show SMILES COc1ccc(cc1CO)-c1cc2nc(nc(N3C[C@H](C)O[C@H](C)C3)c2cn1)N1CCOC[C@@H]1C
Show InChI InChI=1S/C26H33N5O4/c1-16-15-34-8-7-31(16)26-28-23-10-22(19-5-6-24(33-4)20(9-19)14-32)27-11-21(23)25(29-26)30-12-17(2)35-18(3)13-30/h5-6,9-11,16-18,32H,7-8,12-15H2,1-4H3/t16-,17-,18+/m0/s1
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n/an/a 1.63E+3n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351969
PNG
(Preparation of 4,4′-(7-phenylpyrimido[4,5-d]...)
Show SMILES C1CN(CCO1)c1nc(N2CCOCC2)c2cnc(nc2n1)-c1ccccc1
Show InChI InChI=1S/C20H22N6O2/c1-2-4-15(5-3-1)17-21-14-16-18(22-17)23-20(26-8-12-28-13-9-26)24-19(16)25-6-10-27-11-7-25/h1-5,14H,6-13H2
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n/an/a 1.70E+3n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351937
PNG
(Preparation of 5-(2-((1R,5S)-3-oxa-8-azabicyclo[3....)
Show SMILES COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1C2CCC1COC2)N1C[C@H](C)O[C@H](C)C1
Show InChI InChI=1S/C27H33N5O4/c1-16-11-31(12-17(2)36-16)26-22-7-8-23(18-4-9-24(34-3)19(10-18)13-33)28-25(22)29-27(30-26)32-20-5-6-21(32)15-35-14-20/h4,7-10,16-17,20-21,33H,5-6,11-15H2,1-3H3/t16-,17+,20?,21?
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n/an/a 4.87E+3n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM351947
PNG
(Preparation of (5-(2,4-di((2S,6R)-2,6-dimethyl)pyr...)
Show SMILES COc1ccc(cc1CO)-c1cc2nc(nc(N3C[C@H](C)O[C@H](C)C3)c2cn1)N1C[C@H](C)O[C@H](C)C1
Show InChI InChI=1S/C27H35N5O4/c1-16-11-31(12-17(2)35-16)26-22-10-28-23(20-6-7-25(34-5)21(8-20)15-33)9-24(22)29-27(30-26)32-13-18(3)36-19(4)14-32/h6-10,16-19,33H,11-15H2,1-5H3/t16-,17+,18-,19+
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n/an/a>2.00E+4n/an/an/an/an/an/a



SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD.

US Patent


Assay Description
The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...


US Patent US9796732 (2017)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%