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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355969 ((S)-1-(5-chloro-6- (difluoromethoxy) pyridin-3-yl)...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00100 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355967 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00200 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355885 ((S)-1-(5-chloro-6- methoxypyridin-3- yl)-3-(2-chlo...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00200 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355892 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00200 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355970 ((S)-1-(6-(2H-1,2,3- triazol-2-yl)-5- (trifluoromet...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00200 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355886 ((S)-1-(5-chloro-6- (2H-1,2,3-triazol-2- yl)pyridin...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00200 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355971 ((S)-1-(5-chloro-6- (2H-1,2,3-triazol-2- yl)pyridin...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00200 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355980 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00200 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM50169049 (CHEMBL3806155 | US9815842, Example 1) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.00200 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355889 ((S)-methyl 3-chloro- 5-(3-(2-chloro-7-(1- methoxye...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00200 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355950 ((S)-1-(5-chloro-6- (2H-1,2,3-triazol-2- yl)pyridin...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00200 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355897 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355911 (1-(7-(sec-butyl)-2- chloropyrazolo[1,5- a]pyrimidi...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355987 ((R)-1-(6-(2H-1,2,3- triazol-2-yl)-5- (trifluoromet...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355896 (1-(3-chloro-4-(2H- 1,2,3-triazol-2- yl)phenyl)-3-(...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355948 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355894 (1-(5-chloro-6- methoxypyridin-3- yl)-3-(2-chloro-7...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355895 (1-(2-chloro-7- isopropylpyrazolo[1, 5-a]pyrimidin-...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355906 (1-(2-chloro-7- isopropylpyrazolo[1, 5-a]pyrimidin-...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355965 ((S)-1-(2-chloro-7-(1- methoxyethyl)pyrazo- lo[1,5-...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355973 ((S)-1-(5-chloro-6- (difluoromethoxy)py- ridin-3-yl...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355915 ((S)-1-(5-chloro-6- (2H-1,2,3-triazol-2- yl)pyridin...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355925 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355890 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355921 ((R)-1-(5-chloro-6- (2H-1,2,3-triazol-2- yl)pyridin...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355978 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355898 (1-(5-chloro-6-(4- methyl-2H-1,2,3- triazol-2-yl)py...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00400 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355929 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00400 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM50169052 (CHEMBL3806235 | US9815842, Example 54) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00400 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355920 ((S)-1-(5-chloro-6- (2H-1,2,3-triazol-2- yl)pyridin...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00400 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355878 ((S)-1-(2-chloro-7-(1-methoxyethyl)pyrazolo[1,5-a]p...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00400 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355910 (1-(7-(tert-butyl)-2- chloropyrazolo[1,5- a]pyrimid...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00400 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355899 (1-(4-(2- aminopyrimidin-4- yl)-3-chlorophenyl)- 3-...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00400 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355881 ((R)-1-(5-chloro-6-(2H-1,2,3-triazol-2-yl)pyridin-3...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355951 ((S)-1-(2-chloro-7-(1- methoxy-2- methylpropyl)pyra...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355974 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355900 (1-(5-chloro-1- methyl-6-oxo-2-(1H- pyrazol-1-yl)-1...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355947 ((S)-1-(5-chloro-6- (2H-1,2,3-triazol-2- yl)pyridin...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355979 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355957 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355891 (1-(2-chloro-7-(2- methoxypropan-2- yl)pyrazolo[1,5...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355901 (1-(5-chloro-6- ethoxypyridin-3-yl)- 3-(2-chloro-7-...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355902 (1-(5-bromopyridin-3- yl)-3-(2-chloro-7- isopropylp...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355914 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355931 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355932 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355977 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM356002 ((R)-1-(5-chloro-6-(2H-1,2,3-triazol-2-yl)pyridin-3...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355961 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355928 (1-(4-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355880 ((R)-1-(6-(2H-1,2,3-triazol-2-yl)-5-(trifluoromethy...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00600 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM50169051 (CHEMBL3805576 | US9815842, Example 27) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.00600 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355927 (1-(2-chloro-7-(1- (methoxymethyl)cyclo- butyl)pyra...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00600 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355953 (1-(2-chloro-7-(1- (methoxymethyl)cyclo- propyl)pyr...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00600 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355952 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00600 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355916 ((S)-1-(5-chloro-6- methoxypyridin-3- yl)-3-(2-chlo...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00600 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355990 ((S)-1-(2-chloro-7-(1-hydroxyethyl)pyrazolo[1,5-a]p...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00700 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355963 (1-(5-chloro-6- methoxypyridin-3- yl)-3-(2-chloro-7...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00700 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355884 ((S)-1-(2-chloro-7-(1-methoxyethyl)pyrazolo[1,5-a]p...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00700 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355883 ((S)-1-(2-fluoro-7-(1-methoxyethyl)pyrazolo[1,5-a]p...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00800 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355982 (1-(2-chloro-7-(2- (methoxymethyl)tetra- hydrofuran...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00800 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355984 (1-(6-(2H-1,2,3- triazol-2-yl)-5- (trifluoromethyl)...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00800 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355998 ((S)-1-(5-chloro-6-(2H-1,2,3-triazol-2-yl)pyridin-3...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00800 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355993 (1-(4-(4-(aminomethyl)-1H-pyrazol-1-yl)-3-chlorophe...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00800 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355939 (1-(6-(2H-1,2,3- triazol-2-yl)-5- (trifluoromethyl)...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00800 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM356000 ((S)-1-(5-chloro-6-(2H-1,2,3-triazol-2-yl)pyridin-3...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00800 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM356001 (1-(5-chloro-6-(2H-1,2,3-triazol-2-yl)pyridin-3-yl)...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00900 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355904 (1-(3-chloro-4-(3- (hydroxymethyl)-5- methyl-1H-pyr...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00900 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355912 (1-(2-chloro-7-(2- methyltetrahydrofuran- 2-yl)pyra...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00900 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355941 ((R)-1-(6-(2H-1,2,3- triazol-2-yl)-5- (trifluoromet...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00900 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355968 ((S)-1-(2-chloro-7-(1- methoxyethyl)pyrazo- lo[1,5-...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00900 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355934 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00900 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355986 ((S)-1-(6-(2H-1,2,3- triazol-2-yl)-5- (trilfuoromet...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00900 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355919 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00900 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355996 (2-(3-(2-chloro-7-isopropylpyrazolo[1,5-a]pyrimidin...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00900 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM356003 ((S)-1-(5-chloro-6-(2H-1,2,3-triazol-2-yl)pyridin-3...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00900 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355882 ((S)-1-(7-(1-methoxyethyl)-2-methylpyrazolo[1,5-a]p...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355972 ((S)-1-(5-chloro-6- (2H-1,2,3-tirazol-2- yl)pyridin...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355913 ((R)-1-(2-chloro-7-(1- methoxy-2- methylpropyl)pyra...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0110 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355893 (1-(2-chloro-7-(1- methylcyclopropyl) pyrazolo[1,5-...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0110 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355941 ((R)-1-(6-(2H-1,2,3- triazol-2-yl)-5- (trifluoromet...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0110 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355981 ((S)-1-(2-chloro-7-(1- methoxyethyl)pyrazo- lo[1,5-...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0110 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355995 ((S)-1-(5-chloro-6-(2H-1,2,3-triazol-2-yl)pyridin-3...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0120 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355949 (1-(5-chloro-6- methoxypyridin-3- yl)-3-(2-methyl-7...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0120 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355940 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0130 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355922 ((R)-1-(5-chloro-6- (2H-1,2,3-triazol-2- yl)pyridin...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0130 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355983 (1-(6-(2H-1,2,3- triazol-2-yl)-5- (trifluoromethyl)...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0130 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355964 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0140 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355879 ((S)-1-(2-chloro-7-(1-methoxyethyl)pyrazolo[1,5-a]p...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0140 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355888 ((S)-1-(2-chloro-7-(1- methoxyethyl)pyrazo- lo[1,5-...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0140 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355907 (1-(5-chloro-2- oxoindolin-7-yl)-3-(2- chloro-7- is...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0140 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355988 (1-(5-(2H-1,2,3-triazol-2-yl)-2-(trifluoromethyl)py...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0160 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355942 (US9815842, Example 66 | tert-butyl 2-(2- chloro-6-...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0180 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355933 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0190 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355960 ((S)-1-(5-chloro-6- (2H-1,2,3-triazol-2- yl)pyridin...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0190 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355908 (1-(2-chloro-7- isopropylpyrazolo[1, 5-a]pyrimidin-...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0190 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355937 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0190 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355935 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0190 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355887 ((S)-1-(2-chloro-7-(1- methoxyethyl)pyrazo- lo[1,5-...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0190 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355976 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0190 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355997 ((R)-1-(5-chloro-6-(2H-1,2,3-triazol-2-yl)pyridin-3...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355926 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355954 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0210 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355918 ((R)-1-(5-chloro-6- (2H-1,2,3-triazol-2- yl)pyridin...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0210 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355975 ((S)-1-(5-chloro-2-(2- (dimethylamino)eth- oxy)pyri...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0210 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355917 ((S)-1-(2-chloro-7-(1- (2- methoxyethoxy)ethyl) pyr...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0240 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355936 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0260 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355994 (1-(6-(4-(aminomethyl)-1H-pyrazol-1-yl)-5-chloropyr...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0280 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355923 ((R)-1-(2-chloro-7-(1- methoxyethyl)pyrazo- lo[1,5-...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0290 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355909 (1-(5-chloro-2-((1- methylpyrrolidin-3- yl)oxy)-6-(...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355956 (1-(2-chloro-7-(2- (tetrahydro-2H- pyran-4-yl)propa...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0340 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355943 (1-(7-(3- oxabicyclo[3.1.0]hex- an-6-yl)-2- chlorop...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0350 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355944 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0390 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355999 (1-(5-chloro-6-(2H-1,2,3-triazol-2-yl)pyridin-3-yl)...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0410 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355938 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0420 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355924 ((R)-1-(2-chloro-7-(1- methoxyethyl)pyrazo- lo[1,5-...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0420 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355955 (1-(7-(1- (methoxymethyl)cyclo- propyl)-2- methylpy...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0450 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355985 (1-(2-chloro-7-(1,2- dimethoxyethyl)pyra- zolo[1,5-...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0530 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355959 (1-(5-chloro-6-(2h- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0550 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355992 (1-(5-chloro-6-(2H-1,2,3-triazol-2-yl)pyridin-3-yl)...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0710 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355991 (1-(5-chloro-6-(2H-1,2,3-triazol-2-yl)pyridin-3-yl)...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0760 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355962 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355945 (1-(5-chloro-6- methoxypyridin-3- yl)-3-(2-chloro-7...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0860 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355966 (1-(2-chloro-7- (methoxy(tetrahydro- 2H-pyran-4- yl...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0970 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355958 ((S)-1-(5-chloro-6- (2H-1,2,3-triazol-2- yl)pyridin...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.122 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355946 (2-chloro-6-(3-(5- chloro-6-(2H-1,2,3- triazol-2-yl...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.123 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human)) | BDBM355905 (1-(5-chloro-6-(1- methyl-1H-pyrazol- 5-yl)pyridin-...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.370 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ... | US Patent US9815842 (2017) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
