Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356152![]() (2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-N-(5-oxo-2-...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0690 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356096![]() (N-(2-((2,5-dioxoimidazolidin-1- yl)methyl)-4-pheny...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0830 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356095![]() (US9815846, Compound 95) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356218![]() (US9815846, Compound 218) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356196![]() (US9815846, Compound 196) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356058![]() (2-fluoro-N-(6-((2- methoxyacetamido)methyl)-2- phe...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356098![]() (N-(6-((2,5-dioxoimidazolidin-1- yl)methyl)-2-pheny...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.220 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356222![]() (2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-N-(2-((2-ox...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.220 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356059![]() (2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-N-(6-((2- (...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.230 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356227![]() (2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-N-(2-((5-ox...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356129![]() (US9815846, Compound 129) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356097![]() (N-(2-((2,4-dioxooxazolidin-3- yl)methyl)-4-phenylp...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356172![]() (2-fluoro-N-(5-(2- hydroxypropan-2-yl)-6'-phenyl- [...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356144![]() (US9815846, Compound 144) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356178![]() (N-(5-(1-aminoethyl)-6'-phenyl- [2,3'-bipyridin]-5'...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356219![]() (2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-N-(2-((2- o...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356226![]() (N-(2-((2,4-dioxo-3,4- dihydropyrimidin-1(2H)- yl)m...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.350 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356215![]() (US9815846, Compound 215) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.360 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356161![]() (2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-N-(5-oxo-2-...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356068![]() (2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-N-(2-((2- (...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356064![]() (2-fluoro-N-(2-((2- methoxyacetamido)methyl)-4- phe...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.440 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356056![]() ((S)-2-fluoro-N-(6-((2- hydroxypropanamido)methyl)-...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.450 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356080![]() (US9815846, Compound 80) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.490 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356164![]() (US9815846, Compound 164) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.510 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356189![]() (US9815846, Compound 189) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.510 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356070![]() (2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-N-(2-((2-(2...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.530 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356105![]() (N-(2-(2-(ethylamino)-2- oxoethyl)-4-phenylpyrimidi...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.530 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356128![]() (US9815846, Compound 128) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.540 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356151![]() (N-(6-acetyl-2-phenyl-5,6,7,8- tetrahydro-1,6-napht...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.540 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356072![]() ((S)-2-fluoro-N-(6-((2-hydroxy- N-methylpropanamido...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.570 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356135![]() (US9815846, Compound 135) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.570 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356198![]() (US9815846, Compound 198) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.570 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356085![]() ((S)-5-(2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-4- (...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.580 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356169![]() (2-(5-(2-fluoro-5-(pyrimidin-2- yl)-4- (trifluorome...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356099![]() (US9815846, Compound 99) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356061![]() ((S or R)-N-(6-((2,3- dihydroxypropanamido)methyl)-...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356228![]() ((R or S)-2-fluoro-N-(2-((5- (hydroxymethyl)-2- oxo...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.660 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356187![]() (US9815846, Compound 187) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.680 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356168![]() (2-fluoro-N-(5-(hydroxymethyl)- 6'-phenyl-[2,3'-bip...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.680 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356034![]() (N-(2-(cyanomethyl)-4- phenylpyrimidin-5-yl)-2-fluo...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.690 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356104![]() (2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-N-(2-(2- (m...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.760 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356154![]() (3-(2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-4- (trif...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.760 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356102![]() (US9815846, Compound 102) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.790 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356061![]() ((S or R)-N-(6-((2,3- dihydroxypropanamido)methyl)-...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.790 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356076![]() (US9815846, Compound 76) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.840 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356156![]() (N-(6-glycyl-2-phenyl-5,6,7,8- tetrahydro-1,6-napht...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356077![]() (2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-N-(2-((2- o...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356220![]() (2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-N-(2-((2- o...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356179![]() (US9815846, Compound 179) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM356073![]() ((R)-N-(2-((2- aminopropanamido)methyl)-4- phenylpy...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ... | US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R | |||||||||||
More data for this Ligand-Target Pair |
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