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Patent code US9856239

Compile Data Set for Download or QSAR
Found 42 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363910
PNG
(US9856239, 21)
Show SMILES OC(=O)CC1(CSc2ccc(F)cc2C2=CC=C(CC2)C#N)CC1
Show InChI InChI=1S/C19H18FNO2S/c20-15-5-6-17(24-12-19(7-8-19)10-18(22)23)16(9-15)14-3-1-13(11-21)2-4-14/h1,3,5-6,9H,2,4,7-8,10,12H2,(H,22,23)
KEGG

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US Patent
n/an/a<100n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363893
PNG
(US9856239, 11 | US9856239, 4)
Show SMILES OC(=O)CC1(CSc2ccncc2-c2ccc(C#N)c3ccccc23)CC1
Show InChI InChI=1S/C22H18N2O2S/c23-12-15-5-6-18(17-4-2-1-3-16(15)17)19-13-24-10-7-20(19)27-14-22(8-9-22)11-21(25)26/h1-7,10,13H,8-9,11,14H2,(H,25,26)
KEGG

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US Patent
n/an/a<100n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363893
PNG
(US9856239, 11 | US9856239, 4)
Show SMILES OC(=O)CC1(CSc2ccncc2-c2ccc(C#N)c3ccccc23)CC1
Show InChI InChI=1S/C22H18N2O2S/c23-12-15-5-6-18(17-4-2-1-3-16(15)17)19-13-24-10-7-20(19)27-14-22(8-9-22)11-21(25)26/h1-7,10,13H,8-9,11,14H2,(H,25,26)
KEGG

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n/an/a<100n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290431
PNG
(CAS No.:1352792-74-5 | RDEA3170 | US10100016, Veri...)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(C#N)c2ccccc12)C(O)=O
Show InChI InChI=1S/C20H16N2O2S/c1-20(2,19(23)24)25-18-9-10-22-12-17(18)16-8-7-13(11-21)14-5-3-4-6-15(14)16/h3-10,12H,1-2H3,(H,23,24)
KEGG

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n/an/a<100n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363907
PNG
(US9856239, 18)
Show SMILES CC(C)(CCC(O)=O)Sc1ccncc1-c1ccc(C#N)c2ccccc12
Show InChI InChI=1S/C22H20N2O2S/c1-22(2,11-9-21(25)26)27-20-10-12-24-14-19(20)18-8-7-15(13-23)16-5-3-4-6-17(16)18/h3-8,10,12,14H,9,11H2,1-2H3,(H,25,26)
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n/an/a<100n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363892
PNG
(US9856239, 3)
Show SMILES OC(=O)CCCSc1ccncc1-c1ccc(C#N)c2ccccc12
Show InChI InChI=1S/C20H16N2O2S/c21-12-14-7-8-17(16-5-2-1-4-15(14)16)18-13-22-10-9-19(18)25-11-3-6-20(23)24/h1-2,4-5,7-10,13H,3,6,11H2,(H,23,24)
KEGG

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n/an/a<100n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363909
PNG
(US9856239, 20)
Show SMILES OC(=O)CC1(CSc2ccncc2-c2ccc(cc2)C#N)CC1
Show InChI InChI=1S/C18H16N2O2S/c19-10-13-1-3-14(4-2-13)15-11-20-8-5-16(15)23-12-18(6-7-18)9-17(21)22/h1-5,8,11H,6-7,9,12H2,(H,21,22)
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n/an/a<100n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363890
PNG
(US9856239, 1)
Show SMILES OC(=O)C1(CSc2ccncc2-c2ccc(C#N)c3ccccc23)CC1
Show InChI InChI=1S/C21H16N2O2S/c22-11-14-5-6-17(16-4-2-1-3-15(14)16)18-12-23-10-7-19(18)26-13-21(8-9-21)20(24)25/h1-7,10,12H,8-9,13H2,(H,24,25)
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n/an/a<100n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290431
PNG
(CAS No.:1352792-74-5 | RDEA3170 | US10100016, Veri...)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(C#N)c2ccccc12)C(O)=O
Show InChI InChI=1S/C20H16N2O2S/c1-20(2,19(23)24)25-18-9-10-22-12-17(18)16-8-7-13(11-21)14-5-3-4-6-15(14)16/h3-10,12H,1-2H3,(H,23,24)
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n/an/a<100n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363905
PNG
(US9856239, 16)
Show SMILES OC(=O)C1(CSc2ccncc2-c2ccc(C#N)c3ccccc23)CCCC1
Show InChI InChI=1S/C23H20N2O2S/c24-13-16-7-8-19(18-6-2-1-5-17(16)18)20-14-25-12-9-21(20)28-15-23(22(26)27)10-3-4-11-23/h1-2,5-9,12,14H,3-4,10-11,15H2,(H,26,27)
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n/an/a<100n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363906
PNG
(US9856239, 17)
Show SMILES OC(=O)C1(CSc2ccncc2-c2ccc(C#N)c3ccccc23)CCC1
Show InChI InChI=1S/C22H18N2O2S/c23-12-15-6-7-18(17-5-2-1-4-16(15)17)19-13-24-11-8-20(19)27-14-22(21(25)26)9-3-10-22/h1-2,4-8,11,13H,3,9-10,14H2,(H,25,26)
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n/an/a<100n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363902
PNG
(US9856239, 13)
Show SMILES OC(=O)c1ccccc1Sc1ccncc1-c1ccc(C#N)c2ccccc12
Show InChI InChI=1S/C23H14N2O2S/c24-13-15-9-10-18(17-6-2-1-5-16(15)17)20-14-25-12-11-22(20)28-21-8-4-3-7-19(21)23(26)27/h1-12,14H,(H,26,27)
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n/an/a 550n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363901
PNG
(US9856239, 12)
Show SMILES OC(=O)C(F)(F)CCSc1ccncc1-c1ccc(C#N)c2ccccc12
Show InChI InChI=1S/C20H14F2N2O2S/c21-20(22,19(25)26)8-10-27-18-7-9-24-12-17(18)16-6-5-13(11-23)14-3-1-2-4-15(14)16/h1-7,9,12H,8,10H2,(H,25,26)
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n/an/a 550n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363896
PNG
(US9856239, 7)
Show SMILES OC(=O)[C@H]1CC(C1)Sc1ccncc1-c1ccc(C#N)c2ccccc12
Show InChI InChI=1/C21H16N2O2S/c22-11-13-5-6-18(17-4-2-1-3-16(13)17)19-12-23-8-7-20(19)26-15-9-14(10-15)21(24)25/h1-8,12,14-15H,9-10H2,(H,24,25)/t14-,15?
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n/an/a 550n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363891
PNG
(US9856239, 2)
Show SMILES OC(=O)CCSc1ccncc1-c1ccc(C#N)c2ccccc12
Show InChI InChI=1S/C19H14N2O2S/c20-11-13-5-6-16(15-4-2-1-3-14(13)15)17-12-21-9-7-18(17)24-10-8-19(22)23/h1-7,9,12H,8,10H2,(H,22,23)
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n/an/a 550n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363903
PNG
(US9856239, 14)
Show SMILES OC(=O)c1cccc(Sc2ccncc2-c2ccc(C#N)c3ccccc23)c1
Show InChI InChI=1S/C23H14N2O2S/c24-13-16-8-9-20(19-7-2-1-6-18(16)19)21-14-25-11-10-22(21)28-17-5-3-4-15(12-17)23(26)27/h1-12,14H,(H,26,27)
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n/an/a 550n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363894
PNG
(US9856239, 5)
Show SMILES OC(=O)[C@H]1CC(CSc2ccncc2-c2ccc(C#N)c3ccccc23)C1
Show InChI InChI=1/C22H18N2O2S/c23-11-15-5-6-19(18-4-2-1-3-17(15)18)20-12-24-8-7-21(20)27-13-14-9-16(10-14)22(25)26/h1-8,12,14,16H,9-10,13H2,(H,25,26)/t14?,16-
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n/an/a 550n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363923
PNG
(US9856239, 34)
Show SMILES OC(=O)CC1(CSc2ccncc2-c2ccc(cc2)C2(O)CC2)CC1
Show InChI InChI=1S/C20H21NO3S/c22-18(23)11-19(6-7-19)13-25-17-5-10-21-12-16(17)14-1-3-15(4-2-14)20(24)8-9-20/h1-5,10,12,24H,6-9,11,13H2,(H,22,23)
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n/an/a 550n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363922
PNG
(US9856239, 33)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(cc1)C1(O)CC1)C(O)=O
Show InChI InChI=1S/C18H19NO3S/c1-17(2,16(20)21)23-15-7-10-19-11-14(15)12-3-5-13(6-4-12)18(22)8-9-18/h3-7,10-11,22H,8-9H2,1-2H3,(H,20,21)
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n/an/a 550n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363924
PNG
(US9856239, 35)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(cc1)C1(O)COC1)C(O)=O
Show InChI InChI=1S/C18H19NO4S/c1-17(2,16(20)21)24-15-7-8-19-9-14(15)12-3-5-13(6-4-12)18(22)10-23-11-18/h3-9,22H,10-11H2,1-2H3,(H,20,21)
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n/an/a 550n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363904
PNG
(US9856239, 15)
Show SMILES OC(=O)c1ccc(Sc2ccncc2-c2ccc(C#N)c3ccccc23)cc1
Show InChI InChI=1S/C23H14N2O2S/c24-13-16-7-10-20(19-4-2-1-3-18(16)19)21-14-25-12-11-22(21)28-17-8-5-15(6-9-17)23(26)27/h1-12,14H,(H,26,27)
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n/an/a 550n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363911
PNG
(US9856239, 22)
Show SMILES OCC1=CC=C(CC1)c1cnccc1SCC1(CC(O)=O)CC1
Show InChI InChI=1S/C18H21NO3S/c20-11-13-1-3-14(4-2-13)15-10-19-8-5-16(15)23-12-18(6-7-18)9-17(21)22/h1,3,5,8,10,20H,2,4,6-7,9,11-12H2,(H,21,22)
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n/an/a 550n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM50158460
PNG
((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...)
Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1
Show InChI InChI=1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3
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US Patent
n/an/a 550n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363926
PNG
(US9856239, 37)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(cn1)C#N)C(O)=O
Show InChI InChI=1S/C15H13N3O2S/c1-15(2,14(19)20)21-13-5-6-17-9-11(13)12-4-3-10(7-16)8-18-12/h3-6,8-9H,1-2H3,(H,19,20)
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n/an/a>1.00E+3n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363913
PNG
(US9856239, 24 | US9856239, 28)
Show SMILES OC(=O)CNc1ccncc1-c1ccc(cc1)C#N
Show InChI InChI=1S/C14H11N3O2/c15-7-10-1-3-11(4-2-10)12-8-16-6-5-13(12)17-9-14(18)19/h1-6,8H,9H2,(H,16,17)(H,18,19)
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n/an/a>1.00E+3n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363914
PNG
(US9856239, 25)
Show SMILES CC(C)(Nc1ccncc1-c1ccc(cc1)C#N)C(O)=O
Show InChI InChI=1S/C16H15N3O2/c1-16(2,15(20)21)19-14-7-8-18-10-13(14)12-5-3-11(9-17)4-6-12/h3-8,10H,1-2H3,(H,18,19)(H,20,21)
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n/an/a>1.00E+3n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363919
PNG
(US9856239, 30)
Show SMILES OC(=O)CC1(COc2ccncc2-c2ccc(C#N)c3ccccc23)CC1
Show InChI InChI=1S/C22H18N2O3/c23-12-15-5-6-18(17-4-2-1-3-16(15)17)19-13-24-10-7-20(19)27-14-22(8-9-22)11-21(25)26/h1-7,10,13H,8-9,11,14H2,(H,25,26)
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n/an/a>1.00E+3n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290431
PNG
(CAS No.:1352792-74-5 | RDEA3170 | US10100016, Veri...)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(C#N)c2ccccc12)C(O)=O
Show InChI InChI=1S/C20H16N2O2S/c1-20(2,19(23)24)25-18-9-10-22-12-17(18)16-8-7-13(11-21)14-5-3-4-6-15(14)16/h3-10,12H,1-2H3,(H,23,24)
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n/an/a>1.00E+3n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363912
PNG
(US9856239, 23)
Show SMILES OC(=O)CC1(CS(=O)(=O)c2ccccc2-c2ccc(cc2)C#N)CC1
Show InChI InChI=1S/C19H17NO4S/c20-12-14-5-7-15(8-6-14)16-3-1-2-4-17(16)25(23,24)13-19(9-10-19)11-18(21)22/h1-8H,9-11,13H2,(H,21,22)
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n/an/a>1.00E+3n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363916
PNG
(US9856239, 27)
Show SMILES OC(=O)CCCNc1ccncc1-c1ccc(C#N)c2ccccc12
Show InChI InChI=1S/C20H17N3O2/c21-12-14-7-8-17(16-5-2-1-4-15(14)16)18-13-22-11-9-19(18)23-10-3-6-20(24)25/h1-2,4-5,7-9,11,13H,3,6,10H2,(H,22,23)(H,24,25)
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n/an/a>1.00E+3n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363925
PNG
(US9856239, 36)
Show SMILES OC(=O)CC1(CSc2ccncc2-c2ccc(cc2)C2(O)COC2)CC1
Show InChI InChI=1S/C20H21NO4S/c22-18(23)9-19(6-7-19)13-26-17-5-8-21-10-16(17)14-1-3-15(4-2-14)20(24)11-25-12-20/h1-5,8,10,24H,6-7,9,11-13H2,(H,22,23)
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n/an/a>1.00E+3n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363913
PNG
(US9856239, 24 | US9856239, 28)
Show SMILES OC(=O)CNc1ccncc1-c1ccc(cc1)C#N
Show InChI InChI=1S/C14H11N3O2/c15-7-10-1-3-11(4-2-10)12-8-16-6-5-13(12)17-9-14(18)19/h1-6,8H,9H2,(H,16,17)(H,18,19)
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n/an/a>1.00E+3n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363895
PNG
(US9856239, 6)
Show SMILES OC(=O)[C@H]1CC(CSc2ccncc2-c2ccc(C#N)c3ccccc23)C1
Show InChI InChI=1/C22H18N2O2S/c23-11-15-5-6-19(18-4-2-1-3-17(15)18)20-12-24-8-7-21(20)27-13-14-9-16(10-14)22(25)26/h1-8,12,14,16H,9-10,13H2,(H,25,26)/t14?,16-
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n/an/a>1.00E+3n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363908
PNG
(US9856239, 19)
Show SMILES Cc1cc(cnc1-c1cnccc1SC(C)(C)C(O)=O)C#N
Show InChI InChI=1S/C16H15N3O2S/c1-10-6-11(7-17)8-19-14(10)12-9-18-5-4-13(12)22-16(2,3)15(20)21/h4-6,8-9H,1-3H3,(H,20,21)
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n/an/a>1.00E+3n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363898
PNG
(US9856239, 9)
Show SMILES CC(C)(Sc1ccncc1-[n]1N=C(C2CC2)c2ccccc12)C(O)=O
KEGG

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n/an/a>1.00E+3n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363918
PNG
(US9856239, 29)
Show SMILES OC(=O)CC1(COc2ccncc2-c2ccc(cc2)C#N)CC1
Show InChI InChI=1S/C18H16N2O3/c19-10-13-1-3-14(4-2-13)15-11-20-8-5-16(15)23-12-18(6-7-18)9-17(21)22/h1-5,8,11H,6-7,9,12H2,(H,21,22)
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n/an/a>1.00E+3n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363927
PNG
(US9856239, 38)
Show SMILES OC(=O)CC1(CSc2ccncc2-c2ccc(cn2)C#N)CC1
Show InChI InChI=1S/C17H15N3O2S/c18-8-12-1-2-14(20-9-12)13-10-19-6-3-15(13)23-11-17(4-5-17)7-16(21)22/h1-3,6,9-10H,4-5,7,11H2,(H,21,22)
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n/an/a>1.00E+3n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363915
PNG
(US9856239, 26)
Show SMILES OC(=O)CNc1ccncc1-c1ccc(C#N)c2ccccc12
Show InChI InChI=1S/C18H13N3O2/c19-9-12-5-6-15(14-4-2-1-3-13(12)14)16-10-20-8-7-17(16)21-11-18(22)23/h1-8,10H,11H2,(H,20,21)(H,22,23)
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n/an/a>1.00E+3n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363928
PNG
(US9856239, 39)
Show SMILES OC(=O)CC1(CSc2ccncc2-c2ccc(cn2)C(O)=O)CC1
Show InChI InChI=1S/C17H16N2O4S/c20-15(21)7-17(4-5-17)10-24-14-3-6-18-9-12(14)13-2-1-11(8-19-13)16(22)23/h1-3,6,8-9H,4-5,7,10H2,(H,20,21)(H,22,23)
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InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363921
PNG
(US9856239, 32)
Show SMILES OC(=O)CCc1ccncc1-c1ccc(C#N)c2ccccc12
Show InChI InChI=1S/C19H14N2O2/c20-11-14-5-7-17(16-4-2-1-3-15(14)16)18-12-21-10-9-13(18)6-8-19(22)23/h1-5,7,9-10,12H,6,8H2,(H,22,23)
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n/an/a>1.00E+3n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363920
PNG
(US9856239, 31)
Show SMILES CC(C)(Oc1ccncc1-c1ccc(cc1)C#N)C(O)=O
Show InChI InChI=1S/C16H14N2O3/c1-16(2,15(19)20)21-14-7-8-18-10-13(14)12-5-3-11(9-17)4-6-12/h3-8,10H,1-2H3,(H,19,20)
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n/an/a>1.00E+3n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM363899
PNG
(US9856239, 10)
Show SMILES CC(C)(Sc1ccncc1-c1ncc(C#N)c2ccccc12)C(O)=O
Show InChI InChI=1S/C19H15N3O2S/c1-19(2,18(23)24)25-16-7-8-21-11-15(16)17-14-6-4-3-5-13(14)12(9-20)10-22-17/h3-8,10-11H,1-2H3,(H,23,24)
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n/an/a>1.00E+3n/an/an/an/an/an/a



InventisBio Shanghai Ltd.

US Patent


Assay Description
Human kidney embryonic cells HEK-293T were grown in a petri dish (diameter=10 cm) containing DMEM and 10% of bovine fetal serum culture solution, and...


US Patent US9856239 (2018)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%