Compile Data Set for Download or QSAR
maximum 50k data
Found 100 Enz. Inhib. hit(s) with all data for entry = 2425
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364970(4-Amino-6-{3,4-cis-4-[1-(2-azetidin-1-yl-ethyl)-4-...)
Affinity DataIC50: <1nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364970(4-Amino-6-{3,4-cis-4-[1-(2-azetidin-1-yl-ethyl)-4-...)
Affinity DataIC50: <1nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364981(6-{3,4-cis-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluor...)
Affinity DataIC50: <1nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364971(4-Amino-6-{3,4-cis-4-[1-(2-azetidin-1-yl-ethyl)-4-...)
Affinity DataIC50: <1nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364981(6-{3,4-cis-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluor...)
Affinity DataIC50: <1nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364971(4-Amino-6-{3,4-cis-4-[1-(2-azetidin-1-yl-ethyl)-4-...)
Affinity DataIC50: <1nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364972(4-amino-6-[(3R,4S)-4-[1-[2-(azetidin-1-yl)ethyl]-4...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364972(4-amino-6-[(3R,4S)-4-[1-[2-(azetidin-1-yl)ethyl]-4...)
Affinity DataIC50:  5.5nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364973(4-amino-6-[(3S,4R)-4-[1-[2-(azetidin-1-yl)ethyl]-4...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364974(4-Amino-6-{3,4-cis-4-[1-(2-azetidin-1-yl-ethyl)-4-...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364976(4-amino-6-{3,4-trans-4-[1-(2-azetidin-1-yl-ethyl)-...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364978(4-Amino-6-{3,4-trans-4-[1-(2-azetidin-1-yl-ethyl)-...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364979(4-amino-6-{3,4-cis-4-[1-(2-dimethylaminoethyl)-4-(...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364979(4-amino-6-{3,4-cis-4-[1-(2-dimethylaminoethyl)-4-(...)
Affinity DataIC50:  5.5nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364982(6-{3,4-trans-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-flu...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364982(6-{3,4-trans-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-flu...)
Affinity DataIC50:  5.5nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364983(5-chloro-6-{3,4-cis-4-[1-(2-dimethylamino-ethyl)-4...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364983(5-chloro-6-{3,4-cis-4-[1-(2-dimethylamino-ethyl)-4...)
Affinity DataIC50:  5.5nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364985(6-{3,4-cis-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluor...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364985(6-{3,4-cis-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluor...)
Affinity DataIC50:  5.5nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364987(4-Amino-6-{3,4-cis-4-[1-(2-dimethylamino-ethyl)-4-...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364987(4-Amino-6-{3,4-cis-4-[1-(2-dimethylamino-ethyl)-4-...)
Affinity DataIC50:  5.5nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364988(4-Amino-6-{3,4-cis-4-[1-(2-dimethylamino-ethyl)-4-...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364989(6-{3,4-cis-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluor...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364989(6-{3,4-cis-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluor...)
Affinity DataIC50:  5.5nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364993(6-{cis-4-[1-(2-Dimethylamino-ethyl)-4-(4-fluoro-3-...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365002(4-Amino-6-{cis-4-[1-(2-azetidin-1-yl-ethyl)-4-(4-f...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365002(4-Amino-6-{cis-4-[1-(2-azetidin-1-yl-ethyl)-4-(4-f...)
Affinity DataIC50:  5.5nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365003(4-Amino-6-{cis-4-[1-(2-azetidin-1-yl-ethyl)-4-(4-f...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365003(4-Amino-6-{cis-4-[1-(2-azetidin-1-yl-ethyl)-4-(4-f...)
Affinity DataIC50:  5.5nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365004(4-Amino-6-{(3S,4R)-4-[1-(2-dimethylamino-ethyl)-4-...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365004(4-Amino-6-{(3S,4R)-4-[1-(2-dimethylamino-ethyl)-4-...)
Affinity DataIC50:  5.5nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365007(4-Amino-6-{(3R,4S)-4-[1-(2-dimethylamino-ethyl)-4-...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365009(6-{(3R,4S)-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluor...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365009(6-{(3R,4S)-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluor...)
Affinity DataIC50:  5.5nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365010(6-{(3S,4R)-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluor...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365010(6-{(3S,4R)-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluor...)
Affinity DataIC50:  5.5nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365012(6-{cis-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluoro-3-...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365012(6-{cis-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluoro-3-...)
Affinity DataIC50:  5.5nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365014(5-Chloro-6-cis-4-[1-(2-dimethylamino-ethyl)-4-(4-f...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365014(5-Chloro-6-cis-4-[1-(2-dimethylamino-ethyl)-4-(4-f...)
Affinity DataIC50:  5.5nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365016(6-{cis-3-Fluoro-4-[4-(4-fluoro-3-trifluoromethyl-p...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365003(4-Amino-6-{cis-4-[1-(2-azetidin-1-yl-ethyl)-4-(4-f...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365003(4-Amino-6-{cis-4-[1-(2-azetidin-1-yl-ethyl)-4-(4-f...)
Affinity DataIC50:  5.5nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365019(5-Chloro-6-{(3R,4S)-4-[1-(2-dimethylamino-ethyl)-4...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365019(5-Chloro-6-{(3R,4S)-4-[1-(2-dimethylamino-ethyl)-4...)
Affinity DataIC50:  5.5nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365731(5-Chloro-6-{(3S,4R)-4-[1-(2-dimethylamino-ethyl)-4...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM365732(6-{(3S,4R)-4-[1-(2-Dimethylamino-ethyl)-4-(4-fluor...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364993(6-{cis-4-[1-(2-Dimethylamino-ethyl)-4-(4-fluoro-3-...)
Affinity DataIC50:  5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM364993(6-{cis-4-[1-(2-Dimethylamino-ethyl)-4-(4-fluoro-3-...)
Affinity DataIC50:  5.5nMAssay Description:AKT: A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose respon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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