Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 2784
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380541(2-Amino-N,N-dipropyl-8-(3-sulfamoylphenyl)-3H-1-be...)
Affinity DataEC50:  6nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380614(2-Amino-8-[3-[(3R)-3-hydroxypyrrolidin-1-yl]sulfon...)
Affinity DataEC50:  1.30E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380542(2-Amino-8-[3-(2-hydroxyethylsulfamoyl)phenyl]-N,N-...)
Affinity DataEC50:  6nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380542(2-Amino-8-[3-(2-hydroxyethylsulfamoyl)phenyl]-N,N-...)
Affinity DataEC50:  7.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380546(2-amino-N,N-dipropyl-8-(3-pyrrolidin-1-ylsulfonylp...)
Affinity DataEC50:  6nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380546(2-amino-N,N-dipropyl-8-(3-pyrrolidin-1-ylsulfonylp...)
Affinity DataEC50: >1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380584(2-Amino-N,N-dipropyl-8-(5-sulfamoyl-3-pyridyl)-3H-...)
Affinity DataEC50:  23nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380584(2-Amino-N,N-dipropyl-8-(5-sulfamoyl-3-pyridyl)-3H-...)
Affinity DataEC50:  5.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380596(2-Amino-8-[3-(3-hydroxypyrrolidin-1-yl)sulfonylphe...)
Affinity DataEC50:  3nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380596(2-Amino-8-[3-(3-hydroxypyrrolidin-1-yl)sulfonylphe...)
Affinity DataEC50:  1.03E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380597(2-Amino-8-[4-(3-hydroxypyrrolidin-1-yl)sulfonylphe...)
Affinity DataEC50:  10nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380597(2-Amino-8-[4-(3-hydroxypyrrolidin-1-yl)sulfonylphe...)
Affinity DataEC50:  1.04E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380598(2-Amino-8-[3-[(3R)-3-hydroxypyrrolidin-1-yl]sulfon...)
Affinity DataEC50:  5nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380598(2-Amino-8-[3-[(3R)-3-hydroxypyrrolidin-1-yl]sulfon...)
Affinity DataEC50:  1.80E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380599(2-Amino-8-[3-[(3S)-3-hydroxypyrrolidin-1-yl]sulfon...)
Affinity DataEC50:  5nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380599(2-Amino-8-[3-[(3S)-3-hydroxypyrrolidin-1-yl]sulfon...)
Affinity DataEC50:  2.40E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380600(2-Amino-8-[3-(3-hydroxyazetidin-1-yl)sulfonylpheny...)
Affinity DataEC50:  5nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380600(2-Amino-8-[3-(3-hydroxyazetidin-1-yl)sulfonylpheny...)
Affinity DataEC50:  1.70E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380601(2-Amino-8-[3-[2-hydroxyethyl(methyl)sulfamoyl]phen...)
Affinity DataEC50:  4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380601(2-Amino-8-[3-[2-hydroxyethyl(methyl)sulfamoyl]phen...)
Affinity DataEC50:  2.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380602(2-Amino-8-[3-[2-(2-hydroxyethoxy)ethylsulfamoyl]ph...)
Affinity DataEC50:  8nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380602(2-Amino-8-[3-[2-(2-hydroxyethoxy)ethylsulfamoyl]ph...)
Affinity DataEC50:  1.20E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380603(2-Amino-8-[3-(6-hydroxyhexylsulfamoyl)phenyl]-N,N-...)
Affinity DataEC50:  8nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380603(2-Amino-8-[3-(6-hydroxyhexylsulfamoyl)phenyl]-N,N-...)
Affinity DataEC50:  1.20E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380604(2-Amino-8-[3-[(4-hydroxy-1-piperidyl)sulfonyl]phen...)
Affinity DataEC50:  4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380604(2-Amino-8-[3-[(4-hydroxy-1-piperidyl)sulfonyl]phen...)
Affinity DataEC50:  1.70E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380605(2-Amino-8-[3-[(3R)-3-hydroxypyrrolidin-1-yl]sulfon...)
Affinity DataEC50:  9nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380605(2-Amino-8-[3-[(3R)-3-hydroxypyrrolidin-1-yl]sulfon...)
Affinity DataEC50: >1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380606(2-Amino-8-[3-[(3R)-3-hydroxypyrrolidin-1-yl]sulfon...)
Affinity DataEC50:  4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380606(2-Amino-8-[3-[(3R)-3-hydroxypyrrolidin-1-yl]sulfon...)
Affinity DataEC50:  1.70E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380607(2-Amino-8-[3-[3-(hydroxymethyl)azetidin-1-yl]sulfo...)
Affinity DataEC50:  2nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380607(2-Amino-8-[3-[3-(hydroxymethyl)azetidin-1-yl]sulfo...)
Affinity DataEC50:  2.60E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380608(2-Amino-8-[3-[[(3R)-3-hydroxy-1-piperidyl]sulfonyl...)
Affinity DataEC50:  5nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380608(2-Amino-8-[3-[[(3R)-3-hydroxy-1-piperidyl]sulfonyl...)
Affinity DataEC50: >1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380609(2-Amino-8-[3-[[(3S)-3-hydroxy-1-piperidyl]sulfonyl...)
Affinity DataEC50:  6nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380609(2-Amino-8-[3-[[(3S)-3-hydroxy-1-piperidyl]sulfonyl...)
Affinity DataEC50: >1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380610(2-Amino-8-[3-[(3R)-3-hydroxypyrrolidin-1-yl]sulfon...)
Affinity DataEC50:  9nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380610(2-Amino-8-[3-[(3R)-3-hydroxypyrrolidin-1-yl]sulfon...)
Affinity DataEC50:  1.40E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380611(2-Amino-8-(5-piperazin-1-ylsulfonyl-3-pyridyl)-N,N...)
Affinity DataEC50:  17nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380611(2-Amino-8-(5-piperazin-1-ylsulfonyl-3-pyridyl)-N,N...)
Affinity DataEC50:  5.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380612(2-Amino-8-(3-piperazin-1-ylsulfonylphenyl)-N,N-dip...)
Affinity DataEC50:  18nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380612(2-Amino-8-(3-piperazin-1-ylsulfonylphenyl)-N,N-dip...)
Affinity DataEC50: >1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380613(2-Amino-8-[5-(3-aminopyrrolidin-1-yl)sulfonyl-3-py...)
Affinity DataEC50:  31nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380613(2-Amino-8-[5-(3-aminopyrrolidin-1-yl)sulfonyl-3-py...)
Affinity DataEC50:  1.70E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380614(2-Amino-8-[3-[(3R)-3-hydroxypyrrolidin-1-yl]sulfon...)
Affinity DataEC50:  6nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM380541(2-Amino-N,N-dipropyl-8-(3-sulfamoylphenyl)-3H-1-be...)
Affinity DataEC50:  3.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent