Affinity Data by Patent

Patent code US9902710

Found 169 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194437 (US9200016, 119 \| US9902710, Compound 119) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194477 (US9200016, 159 \| US9902710, Compound 159) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.420	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194402 (US9200016, 84 \| US9902710, Compound 84) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.530	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194474 (US9200016, 156 \| US9902710, Compound 156) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194403 (US9200016, 85 \| US9902710, Compound 85) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.820	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194392 (US9200016, 74 \| US9902710, Compound 74) Show SMILES COc1cc2cncc(Cc3cnc4cc(C)ccc4c3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194391 (US9200016, 139 \| US9200016, 73 \| US9902710, Compou...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194463 (US9200016, 145 \| US9902710, Compound 145) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194436 (US9200016, 118 \| US9902710, Compound 118) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194456 (US9200016, 138 \| US9902710, Compound 138) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194455 (US9200016, 137 \| US9902710, Compound 137) Show SMILES COc1cc2cncc(Cc3cnc4ccc(O)cc4c3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194416 (US9200016, 98 \| US9902710, Compound 98) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194407 (US9200016, 89 \| US9902710, Compound 89) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194399 (US9200016, 81 \| US9902710, Compound 81) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194423 (US9200016, 105 \| US9902710, Compound 105) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194400 (US9200016, 82 \| US9902710, Compound 82) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194487 (US9200016, 169 \| US9902710, Compound 169) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194418 (US9200016, 100 \| US9902710, Compound 100) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194464 (US9200016, 146 \| US9902710, Compound 146) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194439 (US9200016, 121 \| US9902710, Compound 121) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194426 (US9200016, 108 \| US9902710, Compound 108) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194440 (US9200016, 122 \| US9902710, Compound 122) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194397 (US9200016, 79 \| US9902710, Compound 79) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194387 (US9200016, 69 \| US9902710, Compound 69) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194391 (US9200016, 139 \| US9200016, 73 \| US9902710, Compou...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194486 (US9200016, 168 \| US9902710, Compound 168) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194479 (US9200016, 161 \| US9902710, Compound 161) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM373566 (US9902710, Compound 48) Show SMILES COc1cc2cncc(Cc3ccc4nc(C)ccc4n3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194462 (US9200016, 144 \| US9902710, Compound 144) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194393 (US9200016, 75 \| US9902710, Compound 75) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194435 (US9200016, 117 \| US9902710, Compound 117) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194328 (US9200016, 10 \| US9902710, Compound 10) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194425 (US9200016, 107 \| US9902710, Compound 107) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194468 (US9200016, 150 \| US9902710, Compound 150) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194404 (US9200016, 86 \| US9902710, Compound 86) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194485 (US9200016, 167 \| US9902710, Compound 167) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194461 (US9200016, 143 \| US9902710, Compound 143) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194447 (US9200016, 129 \| US9902710, Compound 129) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194395 (US9200016, 77 \| US9902710, Compound 77) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194401 (US9200016, 83 \| US9902710, Compound 83) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194362 (US9200016, 44 \| US9902710, Compound 44) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194394 (US9200016, 106 \| US9200016, 76 \| US9902710, Compou...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194414 (US9200016, 96 \| US9902710, Compound 96) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194480 (US9200016, 162 \| US9902710, Compound 162) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194320 (US9200016, 2 \| US9902710, Compound 2) Show SMILES COc1cc2cncc(Cc3cnc4ccccc4c3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194412 (US9200016, 94 \| US9902710, Compound 94) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194470 (US9200016, 152 \| US9902710, Compound 152) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194475 (US9200016, 157 \| US9902710, Compound 157) Show SMILES COc1cc2cncc(Cc3ccc4cccc(N)c4n3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM373685 (US9902710, Compound 160) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194415 (US9200016, 97 \| US9902710, Compound 97) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194417 (US9200016, 99 \| US9902710, Compound 99) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194406 (US9200016, 88 \| US9902710, Compound 88) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194411 (US9200016, 93 \| US9902710, Compound 93) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194473 (US9200016, 155 \| US9902710, Compound 155) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194326 (US9200016, 8 \| US9902710, Compound 8) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194481 (US9200016, 163 \| US9902710, Compound 163) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194368 (US9200016, 50 \| US9902710, Compound 50) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194460 (US9200016, 142 \| US9902710, Compound 142) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194363 (US9200016, 45 \| US9902710, Compound 45) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194488 (US9200016, 170 \| US9902710, Compound 170) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194375 (US9200016, 57 \| US9902710, Compound 57) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194421 (US9200016, 103 \| US9902710, Compound 103) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194434 (US9200016, 116 \| US9902710, Compound 116) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194379 (US9200016, 61 \| US9902710, Compound 61) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194482 (US9200016, 164 \| US9902710, Compound 164) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194364 (US9200016, 46 \| US9902710, Compound 46) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194325 (US9200016, 7 \| US9902710, Compound 7) Show SMILES COc1cc2cncc(Cc3ccc4cccc(O)c4n3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194371 (US9200016, 53 \| US9902710, Compound 53) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194396 (US9200016, 78 \| US9902710, Compound 78) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM373533 (US9902710, Compound 14) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194422 (US9200016, 104 \| US9902710, Compound 104) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194376 (US9200016, 58 \| US9902710, Compound 58) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194469 (US9200016, 151 \| US9902710, Compound 151) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194413 (US9200016, 95 \| US9902710, Compound 95) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194484 (US9200016, 166 \| US9902710, Compound 166) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM373625 (US9902710, Compound 106) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194384 (US9200016, 66 \| US9902710, Compound 66) Show SMILES COc1cc2cncc(Cc3cc4ccccc4cn3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194386 (US9200016, 68 \| US9902710, Compound 68) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194353 (US9200016, 35 \| US9902710, Compound 35) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194445 (US9200016, 127 \| US9902710, Compound 127) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194428 (US9200016, 110 \| US9902710, Compound 110) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194390 (US9200016, 72 \| US9902710, Compound 72) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194430 (US9200016, 112 \| US9902710, Compound 112) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194431 (US9200016, 113 \| US9902710, Compound 113) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194429 (US9200016, 111 \| US9902710, Compound 111) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194365 (US9200016, 47 \| US9902710, Compound 47) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194420 (US9200016, 102 \| US9902710, Compound 102) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194361 (US9200016, 43 \| US9902710, Compound 43) Show SMILES COc1cc2cnc(C)c(Cc3cnc4ccccc4c3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194398 (US9200016, 80 \| US9902710, Compound 80) Show SMILES COc1cc2cncc(Cc3coc4ccccc4c3=O)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194442 (US9200016, 124 \| US9902710, Compound 124) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194380 (US9200016, 62 \| US9902710, Compound 62) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194449 (US9200016, 131 \| US9902710, Compound 131) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194360 (US9200016, 42 \| US9902710, Compound 42) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194419 (US9200016, 101 \| US9902710, Compound 101) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194369 (US9200016, 51 \| US9902710, Compound 51) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194339 (US9200016, 21 \| US9902710, Compound 21) Show SMILES COc1cc2cncc(Cc3ccc4cccc(OC)c4n3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194408 (US9200016, 90 \| US9902710, Compound 90) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194345 (US9200016, 27 \| US9902710, Compound 27) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194467 (US9200016, 149 \| US9902710, Compound 149) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194344 (US9200016, 26 \| US9902710, Compound 26) Show SMILES COc1cc2c(C)ncc(Cc3cnc4ccccc4c3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194443 (US9200016, 125 \| US9902710, Compound 125) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194359 (US9200016, 41 \| US9902710, Compound 41) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194327 (US9200016, 9 \| US9902710, Compound 9) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194324 (US9200016, 6 \| US9902710, Compound 6) Show SMILES COc1cc2cncc(Cc3ccc4ncccc4c3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194427 (US9200016, 109 \| US9902710, Compound 109) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194405 (US9200016, 87 \| US9902710, Compound 87) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194454 (US9200016, 136 \| US9902710, Compound 136) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194446 (US9200016, 128 \| US9902710, Compound 128) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM373658 (US9902710, Compound 134) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194433 (US9200016, 115 \| US9902710, Compound 115) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194489 (US9200016, 171 \| US9902710, Compound 171) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194367 (US9200016, 49 \| US9902710, Compound 49) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194465 (US9200016, 147 \| US9902710, Compound 147) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194438 (US9200016, 120 \| US9902710, Compound 120) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194374 (US9200016, 56 \| US9902710, Compound 56) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194448 (US9200016, 130 \| US9902710, Compound 130) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194330 (US9200016, 12 \| US9902710, Compound 12) Show SMILES COc1cc2cncc(Cc3ccc4N(C)CCOc4c3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194444 (US9200016, 126 \| US9902710, Compound 126) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194483 (US9200016, 165 \| US9902710, Compound 165) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194333 (US9200016, 15 \| US9902710, Compound 15) Show SMILES COc1cc2cncc(Cc3ccc4[nH]cnc4c3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194409 (US9200016, 91 \| US9902710, Compound 91) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194352 (US9200016, 34 \| US9902710, Compound 34) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194466 (US9200016, 148 \| US9902710, Compound 148) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194342 (US9200016, 24 \| US9902710, Compound 24) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194349 (US9200016, 31 \| US9902710, Compound 31) Show SMILES CCOc1cc2c(Cc3cnc4ccccc4c3)cncc2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194382 (US9200016, 64 \| US9902710, Compound 64) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194337 (US9200016, 19 \| US9902710, Compound 19) Show SMILES COc1cc2cncc(Cc3cc4ccccc4nc3Cl)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194472 (US9200016, 154 \| US9902710, Compound 154) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194370 (US9200016, 52 \| US9902710, Compound 52) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194321 (US9200016, 3 \| US9902710, Compound 3) Show SMILES COc1cc2cncc(Cc3ccc4sccc4c3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194451 (US9200016, 133 \| US9902710, Compound 133) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194319 (US9200016, 1 \| US9902710, Compound 1) Show SMILES COc1cc2cncc(Cc3ccc4ccccc4c3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194458 (US9200016, 140 \| US9902710, Compound 140) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194322 (US9200016, 4 \| US9902710, Compound 4) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194329 (US9200016, 11 \| US9902710, Compound 11) Show SMILES COc1cc2cncc(Cc3ccc4N(C)CCc4c3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194331 (US9200016, 13 \| US9902710, Compound 13) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194377 (US9200016, 59 \| US9902710, Compound 59) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	148	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194471 (US9200016, 153 \| US9902710, Compound 153) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	148	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194441 (US9200016, 123 \| US9902710, Compound 123) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194372 (US9200016, 54 \| US9902710, Compound 54) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194385 (US9200016, 67 \| US9902710, Compound 67) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM373575 (US9902710, Compound 55) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194383 (US9200016, 65 \| US9902710, Compound 65) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	159	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194346 (US9200016, 28 \| US9902710, Compound 28) Show SMILES CCOc1cc2cncc(Cc3cnc4ccccc4c3)c2cc1OCC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	168	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194351 (US9200016, 33 \| US9902710, Compound 33) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194432 (US9200016, 114 \| US9902710, Compound 114) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	189	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM373659 (US9902710, Compound 135) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	192	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194343 (US9200016, 25 \| US9902710, Compound 25) Show SMILES COc1cc2c(C)ncc(Cc3ccc4ccccc4c3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	194	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194476 (US9200016, 158 \| US9902710, Compound 158) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	204	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194323 (US9200016, 5 \| US9902710, Compound 5) Show SMILES COc1cc2cncc(Cc3ccc4ccccc4n3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	208	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194341 (US9200016, 23 \| US9902710, Compound 23) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	213	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194336 (US9200016, 18 \| US9902710, Compound 18) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	238	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194358 (US9200016, 40 \| US9902710, Compound 40) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	278	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194355 (US9200016, 37 \| US9902710, Compound 37) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	287	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194350 (US9200016, 32 \| US9902710, Compound 32) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	315	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194334 (US9200016, 16 \| US9902710, Compound 16) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194357 (US9200016, 39 \| US9902710, Compound 39) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	339	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194378 (US9200016, 60 \| US9902710, Compound 60) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	368	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194450 (US9200016, 132 \| US9902710, Compound 132) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	491	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194410 (US9200016, 92 \| US9902710, Compound 92) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	495	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194388 (US9200016, 70 \| US9902710, Compound 70) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	946	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194340 (US9200016, 22 \| US9902710, Compound 22) Show SMILES COc1cc2cnc(C)c(Cc3ccc4ccccc4c3)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194459 (US9200016, 141 \| US9902710, Compound 141) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194356 (US9200016, 38 \| US9902710, Compound 38) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194335 (US9200016, 17 \| US9902710, Compound 17) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194354 (US9200016, 36 \| US9902710, Compound 36) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194347 (US9200016, 29 \| US9902710, Compound 29) Show SMILES COc1cc2cncc(Cc3cnc4ccccc4c3)c2cc1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194389 (US9200016, 71 \| US9902710, Compound 71) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM194348 (US9200016, 30 \| US9902710, Compound 30) Show SMILES COc1cc2c(Cc3cnc4ccccc4c3)cncc2cc1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				US Patent US9902710 (2018)
EXONHIT THERAPEUTICS, SA; ALLERGAN, INC. US Patent					More data for this Ligand-Target Pair