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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375433 (US9907800, Example A145) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM375434 (US9907800, Example A146) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM50044670 (CHEMBL3353359 | US9907800, Example A147) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375449 (US9907800, Example A159) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM375454 (US9907800, Example A164) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375464 (US9907800, Example A173) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375469 (US9907800, Example A178) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375470 (US9907800, Example A179) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375471 (US9907800, Example A180) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM375471 (US9907800, Example A180) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora A inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM375471 (US9907800, Example A180) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375472 (US9907800, Example A181) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM375479 (US9907800, Example A188) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM375483 (US9907800, Example A192) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM50044668 (CHEMBL3353357 | US9907800, Example A196) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM375488 (US9907800, Example A197) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM375494 (US9907800, Example A203) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM375504 (US9907800, Example A213) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM50044651 (CHEMBL3353349 | US9907800, Example A214) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM375506 (US9907800, Example A215) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora A inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM375507 (US9907800, Example A216) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375508 (US9907800, Example A217) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase receptor FLT3 (Homo sapiens (Human)) | BDBM375291 (US9907800, Example A16) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description The enzymatic activity of FLT3 was determined using the Z-Lyte assay kit from Invitrogen (Invitrogen cat #PV3191). The assay was performed using the ... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase receptor FLT3 (Homo sapiens (Human)) | BDBM375466 (US9907800, Example A175) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description The enzymatic activity of FLT3 was determined using the Z-Lyte assay kit from Invitrogen (Invitrogen cat #PV3191). The assay was performed using the ... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375290 (US9907800, Example A15) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM375291 (US9907800, Example A16) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM375295 (US9907800, Example A20) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375297 (US9907800, Example A22) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM50044660 (CHEMBL3353342 | US9907800, Example A29) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375311 (US9907800, Example A32) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM50044665 (CHEMBL3353341 | US9907800, Example A33) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM50044656 (CHEMBL3353348 | US9907800, Example A35) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM50044656 (CHEMBL3353348 | US9907800, Example A35) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM50044674 (CHEMBL3353355 | US9907800, Example A42) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375326 (US9907800, Example A46) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375327 (US9907800, Example A47) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375333 (US9907800, Example A53) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM375333 (US9907800, Example A53) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM50044675 (CHEMBL3353354 | US9907800, Example A56) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM50044675 (CHEMBL3353354 | US9907800, Example A56) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM50044662 (CHEMBL3353361 | US9907800, Example A61) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM375347 (US9907800, Example A67) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM375352 (US9907800, Example A71) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375354 (US9907800, Example A73) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM375354 (US9907800, Example A73) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B (Homo sapiens (Human)) | BDBM375355 (US9907800, Example A74) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375357 (US9907800, Example A76) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375360 (US9907800, Example A79) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375363 (US9907800, Example A82) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase PLK4 (Homo sapiens (Human)) | BDBM375365 (US9907800, Example A84) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network US Patent | Assay Description PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP... | US Patent US9907800 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
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