Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nuclear receptor subfamily 2 group C member 2 (Homo sapiens (Human)) | BDBM375312![]() (US9908872, Compound (I-9)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.43 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor subfamily 2 group C member 2 (Homo sapiens (Human)) | BDBM375310![]() (US9908872, Compound (I-8)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.33 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor subfamily 2 group C member 2 (Homo sapiens (Human)) | BDBM375276![]() (US9908872, Compound (I-1)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor subfamily 2 group C member 2 (Homo sapiens (Human)) | BDBM375281![]() (US9908872, Compound (I-4)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 22.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM375276![]() (US9908872, Compound (I-1)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 22.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM375312![]() (US9908872, Compound (I-9)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 25.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor subfamily 2 group C member 2 (Homo sapiens (Human)) | BDBM375307![]() (US9908872, Compound (I-6)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 29.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor subfamily 2 group C member 2 (Homo sapiens (Human)) | BDBM375308![]() (US9908872, Compound (I-7)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 56.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor subfamily 2 group C member 2 (Homo sapiens (Human)) | BDBM375280![]() (US9908872, Compound (I-3)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 62.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM375310![]() (US9908872, Compound (I-8)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 69.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor subfamily 2 group C member 2 (Homo sapiens (Human)) | BDBM375299![]() (US9908872, Compound (I-5)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 117 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM375280![]() (US9908872, Compound (I-3)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 196 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM375281![]() (US9908872, Compound (I-4)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 459 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM375307![]() (US9908872, Compound (I-6)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human)) | BDBM375307![]() (US9908872, Compound (I-6)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | >3.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM375308![]() (US9908872, Compound (I-7)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM375299![]() (US9908872, Compound (I-5)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human)) | BDBM375276![]() (US9908872, Compound (I-1)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human)) | BDBM375299![]() (US9908872, Compound (I-5)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Inc US Patent | Assay Description The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening... | US Patent US9908872 (2018) BindingDB Entry DOI: 10.7270/Q2668GH3 | |||||||||||
More data for this Ligand-Target Pair |