Affinity Data by Patent

Patent code US9918974

Found 2 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
RET Kinase (aa658-end) (Homo sapiens (Human))	BDBM376119 (N-(2-(dimethylamino)ethyl)-3-(2-(4-(4-ethoxy-6-oxo...) Show SMILES Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline US Patent					Assay Description Human RET kinase cytoplasmic domain (amino acids 658-1114 of accession number NP_000314.1) was expressed as an N-terminal GST-fusion protein using a ...				US Patent US9918974 (2018) BindingDB Entry DOI: 10.7270/Q2HH6NCH
GlaxoSmithKline US Patent					More data for this Ligand-Target Pair
RET Kinase (aa658-end) (Homo sapiens (Human))	BDBM376389 (N-(3-(2-(dimethylamino)ethoxy)-5-(trifluoromethyl)...) Show SMILES Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline US Patent					Assay Description Human RET kinase cytoplasmic domain (amino acids 658-1114 of accession number NP_000314.1) was expressed as an N-terminal GST-fusion protein using a ...				US Patent US9918974 (2018) BindingDB Entry DOI: 10.7270/Q2HH6NCH
GlaxoSmithKline US Patent					More data for this Ligand-Target Pair

* indicates data uncertainty>20%