BindingDB logo
myBDB logout

Patent code US9944601

Compile Data Set for Download or QSAR
Found 159 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM50142189
PNG
(CHEMBL3759239 | US10329256, Example 5 | US9487512,...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CCNCC1
Show InChI InChI=1/C15H22N2/c1-2-4-13(5-3-1)14-10-15(14)17-11-12-6-8-16-9-7-12/h1-5,12,14-17H,6-11H2/t14-,15+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
55n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM388464
PNG
(US10329256, Example 4 | US9944601, Example 4)
Show SMILES C(Oc1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1)c1ccccc1
Show InChI InChI=1S/C21H26N2O/c1-2-4-16(5-3-1)15-24-19-8-6-17(7-9-19)20-14-21(20)23-18-10-12-22-13-11-18/h1-9,18,20-23H,10-15H2/t20-,21+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
55n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256461
PNG
(US10329256, Example 6 | US9487512, 6 | US9944601, ...)
Show SMILES C(CC1CCNCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H24N2/c1-2-4-14(5-3-1)15-12-16(15)18-11-8-13-6-9-17-10-7-13/h1-5,13,15-18H,6-12H2/t15-,16+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
55n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
55n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256459
PNG
(US10329256, Example 3 | US9487512, 3 | US9944601, ...)
Show SMILES C1[C@@H](NC2CCNCC2)[C@@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
55n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
550n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256464
PNG
(US10329256, Example 9 | US9487512, 9 | US9944601, ...)
Show SMILES Clc1ccc(cc1)-c1ccc(cc1)[C@H]1C[C@@H]1NCCC1CCOCC1
Show InChI InChI=1/C22H26ClNO/c23-20-7-5-18(6-8-20)17-1-3-19(4-2-17)21-15-22(21)24-12-9-16-10-13-25-14-11-16/h1-8,16,21-22,24H,9-15H2/t21-,22+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
550n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256462
PNG
(US10329256, Example 7 | US9487512, 7 | US9944601, ...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cn1)[C@H]1C[C@@H]1NC1CCOCC1
Show InChI InChI=1/C20H21F3N2O/c21-20(22,23)15-3-1-2-13(10-15)18-5-4-14(12-24-18)17-11-19(17)25-16-6-8-26-9-7-16/h1-5,10,12,16-17,19,25H,6-9,11H2/t17-,19+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
550n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256463
PNG
(US10329256, Example 8 | US9487512, 8 | US9944601, ...)
Show SMILES C(CC1CCOCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H23NO/c1-2-4-14(5-3-1)15-12-16(15)17-9-6-13-7-10-18-11-8-13/h1-5,13,15-17H,6-12H2/t15-,16+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+3n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM388464
PNG
(US10329256, Example 4 | US9944601, Example 4)
Show SMILES C(Oc1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1)c1ccccc1
Show InChI InChI=1S/C21H26N2O/c1-2-4-16(5-3-1)15-24-19-8-6-17(7-9-19)20-14-21(20)23-18-10-12-22-13-11-18/h1-9,18,20-23H,10-15H2/t20-,21+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+3n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256462
PNG
(US10329256, Example 7 | US9487512, 7 | US9944601, ...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cn1)[C@H]1C[C@@H]1NC1CCOCC1
Show InChI InChI=1/C20H21F3N2O/c21-20(22,23)15-3-1-2-13(10-15)18-5-4-14(12-24-18)17-11-19(17)25-16-6-8-26-9-7-16/h1-5,10,12,16-17,19,25H,6-9,11H2/t17-,19+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+3n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256464
PNG
(US10329256, Example 9 | US9487512, 9 | US9944601, ...)
Show SMILES Clc1ccc(cc1)-c1ccc(cc1)[C@H]1C[C@@H]1NCCC1CCOCC1
Show InChI InChI=1/C22H26ClNO/c23-20-7-5-18(6-8-20)17-1-3-19(4-2-17)21-15-22(21)24-12-9-16-10-13-25-14-11-16/h1-8,16,21-22,24H,9-15H2/t21-,22+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+3n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50142189
PNG
(CHEMBL3759239 | US10329256, Example 5 | US9487512,...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CCNCC1
Show InChI InChI=1/C15H22N2/c1-2-4-13(5-3-1)14-10-15(14)17-11-12-6-8-16-9-7-12/h1-5,12,14-17H,6-11H2/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
5.50E+4n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256464
PNG
(US10329256, Example 9 | US9487512, 9 | US9944601, ...)
Show SMILES Clc1ccc(cc1)-c1ccc(cc1)[C@H]1C[C@@H]1NCCC1CCOCC1
Show InChI InChI=1/C22H26ClNO/c23-20-7-5-18(6-8-20)17-1-3-19(4-2-17)21-15-22(21)24-12-9-16-10-13-25-14-11-16/h1-8,16,21-22,24H,9-15H2/t21-,22+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+4n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256461
PNG
(US10329256, Example 6 | US9487512, 6 | US9944601, ...)
Show SMILES C(CC1CCNCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H24N2/c1-2-4-14(5-3-1)15-12-16(15)18-11-8-13-6-9-17-10-7-13/h1-5,13,15-18H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+4n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256462
PNG
(US10329256, Example 7 | US9487512, 7 | US9944601, ...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cn1)[C@H]1C[C@@H]1NC1CCOCC1
Show InChI InChI=1/C20H21F3N2O/c21-20(22,23)15-3-1-2-13(10-15)18-5-4-14(12-24-18)17-11-19(17)25-16-6-8-26-9-7-16/h1-5,10,12,16-17,19,25H,6-9,11H2/t17-,19+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+4n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM388464
PNG
(US10329256, Example 4 | US9944601, Example 4)
Show SMILES C(Oc1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1)c1ccccc1
Show InChI InChI=1S/C21H26N2O/c1-2-4-16(5-3-1)15-24-19-8-6-17(7-9-19)20-14-21(20)23-18-10-12-22-13-11-18/h1-9,18,20-23H,10-15H2/t20-,21+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+4n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256463
PNG
(US10329256, Example 8 | US9487512, 8 | US9944601, ...)
Show SMILES C(CC1CCOCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H23NO/c1-2-4-14(5-3-1)15-12-16(15)17-9-6-13-7-10-18-11-8-13/h1-5,13,15-17H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+4n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256461
PNG
(US10329256, Example 6 | US9487512, 6 | US9944601, ...)
Show SMILES C(CC1CCNCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H24N2/c1-2-4-14(5-3-1)15-12-16(15)18-11-8-13-6-9-17-10-7-13/h1-5,13,15-18H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+4n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256463
PNG
(US10329256, Example 8 | US9487512, 8 | US9944601, ...)
Show SMILES C(CC1CCOCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H23NO/c1-2-4-14(5-3-1)15-12-16(15)17-9-6-13-7-10-18-11-8-13/h1-5,13,15-17H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+4n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
>1.00E+5n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
>1.00E+5n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM50142189
PNG
(CHEMBL3759239 | US10329256, Example 5 | US9487512,...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CCNCC1
Show InChI InChI=1/C15H22N2/c1-2-4-13(5-3-1)14-10-15(14)17-11-12-6-8-16-9-7-12/h1-5,12,14-17H,6-11H2/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
>1.00E+5n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
>1.00E+5n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
>1.00E+5n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256459
PNG
(US10329256, Example 3 | US9487512, 3 | US9944601, ...)
Show SMILES C1[C@@H](NC2CCNCC2)[C@@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
>1.00E+5n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256459
PNG
(US10329256, Example 3 | US9487512, 3 | US9944601, ...)
Show SMILES C1[C@@H](NC2CCNCC2)[C@@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
>1.00E+5n/an/an/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256482
PNG
(US10329256, Example 27 | US9487512, 27 | US9944601...)
Show SMILES Fc1ccccc1COc1ccc(cc1)[C@H]1C[C@@H]1NCC1CCNCC1
Show InChI InChI=1/C22H27FN2O/c23-21-4-2-1-3-18(21)15-26-19-7-5-17(6-8-19)20-13-22(20)25-14-16-9-11-24-12-10-16/h1-8,16,20,22,24-25H,9-15H2/t20-,22+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM388464
PNG
(US10329256, Example 4 | US9944601, Example 4)
Show SMILES C(Oc1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1)c1ccccc1
Show InChI InChI=1S/C21H26N2O/c1-2-4-16(5-3-1)15-24-19-8-6-17(7-9-19)20-14-21(20)23-18-10-12-22-13-11-18/h1-9,18,20-23H,10-15H2/t20-,21+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 19n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM50142189
PNG
(CHEMBL3759239 | US10329256, Example 5 | US9487512,...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CCNCC1
Show InChI InChI=1/C15H22N2/c1-2-4-13(5-3-1)14-10-15(14)17-11-12-6-8-16-9-7-12/h1-5,12,14-17H,6-11H2/t14-,15+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 22n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256484
PNG
(US10329256, Example 29 | US9487512, 29 | US9944601...)
Show SMILES COc1ccc(NS(C)(=O)=O)cc1-c1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1
Show InChI InChI=1/C22H29N3O3S/c1-28-22-8-7-18(25-29(2,26)27)13-20(22)16-5-3-15(4-6-16)19-14-21(19)24-17-9-11-23-12-10-17/h3-8,13,17,19,21,23-25H,9-12,14H2,1-2H3/t19-,21+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 23n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256498
PNG
(US10329256, Example 43 | US9487512, 43 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccc(cc1)-c1cccnc1)C1CCNCC1
Show InChI InChI=1/C20H25N3/c1-2-18(14-22-9-1)16-3-5-17(6-4-16)19-12-20(19)23-13-15-7-10-21-11-8-15/h1-6,9,14-15,19-21,23H,7-8,10-13H2/t19-,20+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 32n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256481
PNG
(US10329256, Example 26 | US9487512, 26 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CCNC1
Show InChI InChI=1/C14H20N2/c1-2-4-12(5-3-1)13-8-14(13)16-10-11-6-7-15-9-11/h1-5,11,13-16H,6-10H2/t11?,13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 35n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256497
PNG
(US10329256, Example 42 | US9487512, 42 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccc(cc1)C1CC1)C1CCNCC1
Show InChI InChI=1/C18H26N2/c1-2-14(1)15-3-5-16(6-4-15)17-11-18(17)20-12-13-7-9-19-10-8-13/h3-6,13-14,17-20H,1-2,7-12H2/t17-,18+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 37n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256475
PNG
(US10329256, Example 20 | US9487512, 20 | US9944601...)
Show SMILES Fc1ccccc1C1CC1NC1CCNCC1
Show InChI InChI=1/C14H19FN2/c15-13-4-2-1-3-11(13)12-9-14(12)17-10-5-7-16-8-6-10/h1-4,10,12,14,16-17H,5-9H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 38n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256461
PNG
(US10329256, Example 6 | US9487512, 6 | US9944601, ...)
Show SMILES C(CC1CCNCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H24N2/c1-2-4-14(5-3-1)15-12-16(15)18-11-8-13-6-9-17-10-7-13/h1-5,13,15-18H,6-12H2/t15-,16+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 38n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256486
PNG
(US10329256, Example 31 | US9487512, 31 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CNC1
Show InChI InChI=1/C13H18N2/c1-2-4-11(5-3-1)12-6-13(12)15-9-10-7-14-8-10/h1-5,10,12-15H,6-9H2/t12-,13+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 42n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256459
PNG
(US10329256, Example 3 | US9487512, 3 | US9944601, ...)
Show SMILES C1[C@@H](NC2CCNCC2)[C@@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 42n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256479
PNG
(US10329256, Example 24 | US9487512, 24 | US9944601...)
Show SMILES C1C(NC2CCNCC2)C1c1ccc2ccccc2c1
Show InChI InChI=1/C18H22N2/c1-2-4-14-11-15(6-5-13(14)3-1)17-12-18(17)20-16-7-9-19-10-8-16/h1-6,11,16-20H,7-10,12H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 47n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256470
PNG
(US10329256, Example 15 | US9487512, 15 | US9944601...)
Show SMILES C1[C@H](NC2CC3(C2)CCNCC3)[C@H]1c1ccccc1
Show InChI InChI=1/C17H24N2/c1-2-4-13(5-3-1)15-10-16(15)19-14-11-17(12-14)6-8-18-9-7-17/h1-5,14-16,18-19H,6-12H2/t15-,16+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 48n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 56n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256491
PNG
(US10329256, Example 36 | US9487512, 36 | US9944601...)
Show SMILES CC1(C)CC(CC(C)(C)N1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C18H28N2/c1-17(2)11-14(12-18(3,4)20-17)19-16-10-15(16)13-8-6-5-7-9-13/h5-9,14-16,19-20H,10-12H2,1-4H3/t15-,16+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 68n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256468
PNG
(US10329256, Example 13 | US9487512, 13 | US9944601...)
Show SMILES C1[C@H](NC2CC3CCC(C2)N3)[C@H]1c1ccccc1
Show InChI InChI=1/C16H22N2/c1-2-4-11(5-3-1)15-10-16(15)18-14-8-12-6-7-13(9-14)17-12/h1-5,12-18H,6-10H2/t12?,13?,14?,15-,16+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 69n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256469
PNG
(US10329256, Example 14 | US9487512, 14 | US9944601...)
Show SMILES C1[C@H](NC2CCC3(CCNCC3)CC2)[C@H]1c1ccccc1
Show InChI InChI=1/C19H28N2/c1-2-4-15(5-3-1)17-14-18(17)21-16-6-8-19(9-7-16)10-12-20-13-11-19/h1-5,16-18,20-21H,6-14H2/t17-,18+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 71n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256499
PNG
(US10329256, Example 44 | US9487512, 44 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccc(cc1)-c1ccn[nH]1)C1CCNCC1
Show InChI InChI=1/C18H24N4/c1-3-15(17-7-10-21-22-17)4-2-14(1)16-11-18(16)20-12-13-5-8-19-9-6-13/h1-4,7,10,13,16,18-20H,5-6,8-9,11-12H2,(H,21,22)/t16-,18+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 72n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256473
PNG
(US10329256, Example 18 | US9487512, 18 | US9944601...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1cncs1
Show InChI InChI=1/C11H17N3S/c1-3-12-4-2-8(1)14-10-5-9(10)11-6-13-7-15-11/h6-10,12,14H,1-5H2/t9-,10-/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 81n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256483
PNG
(US10329256, Example 28 | US9487512, 28 | US9944601...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cc1)[C@H]1C[C@@H]1NCC1CCNCC1
Show InChI InChI=1/C22H25F3N2/c23-22(24,25)19-3-1-2-18(12-19)16-4-6-17(7-5-16)20-13-21(20)27-14-15-8-10-26-11-9-15/h1-7,12,15,20-21,26-27H,8-11,13-14H2/t20-,21+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 84n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256480
PNG
(US10329256, Example 25 | US9487512, 25 | US9944601...)
Show SMILES CC1(CC1NC1CCNCC1)c1ccccc1
Show InChI InChI=1/C15H22N2/c1-15(12-5-3-2-4-6-12)11-14(15)17-13-7-9-16-10-8-13/h2-6,13-14,16-17H,7-11H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 97n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256489
PNG
(US10329256, Example 34 | US9487512, 34 | US9944601...)
Show SMILES NC(=O)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(Br)cc1
Show InChI InChI=1/C15H20BrN3O/c16-11-3-1-10(2-4-11)13-9-14(13)18-12-5-7-19(8-6-12)15(17)20/h1-4,12-14,18H,5-9H2,(H2,17,20)/t13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 104n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256474
PNG
(US10329256, Example 19 | US9487512, 19 | US9944601...)
Show SMILES Cc1ccccc1C1CC1NC1CCNCC1
Show InChI InChI=1/C15H22N2/c1-11-4-2-3-5-13(11)14-10-15(14)17-12-6-8-16-9-7-12/h2-5,12,14-17H,6-10H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 105n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256472
PNG
(US10329256, Example 17 | US9487512, 17 | US9944601...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1cccnc1
Show InChI InChI=1/C13H19N3/c1-2-10(9-15-5-1)12-8-13(12)16-11-3-6-14-7-4-11/h1-2,5,9,11-14,16H,3-4,6-8H2/t12-,13+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 107n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256493
PNG
(US10329256, Example 38 | US9487512, 38 | US9944601...)
Show SMILES CC(C)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C17H26N2/c1-13(2)19-10-8-15(9-11-19)18-17-12-16(17)14-6-4-3-5-7-14/h3-7,13,15-18H,8-12H2,1-2H3/t16-,17+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 108n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256485
PNG
(US10329256, Example 30 | US9487512, 30 | US9944601...)
Show SMILES CC(C)S(=O)(=O)Nc1cccc(c1)-c1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1
Show InChI InChI=1/C23H31N3O2S/c1-16(2)29(27,28)26-21-5-3-4-19(14-21)17-6-8-18(9-7-17)22-15-23(22)25-20-10-12-24-13-11-20/h3-9,14,16,20,22-26H,10-13,15H2,1-2H3/t22-,23+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 111n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256462
PNG
(US10329256, Example 7 | US9487512, 7 | US9944601, ...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cn1)[C@H]1C[C@@H]1NC1CCOCC1
Show InChI InChI=1/C20H21F3N2O/c21-20(22,23)15-3-1-2-13(10-15)18-5-4-14(12-24-18)17-11-19(17)25-16-6-8-26-9-7-16/h1-5,10,12,16-17,19,25H,6-9,11H2/t17-,19+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 111n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256477
PNG
(US10329256, Example 22 | US9487512, 22 | US9944601...)
Show SMILES COc1ccc(cc1)C1CC1NC1CCNCC1
Show InChI InChI=1/C15H22N2O/c1-18-13-4-2-11(3-5-13)14-10-15(14)17-12-6-8-16-9-7-12/h2-5,12,14-17H,6-10H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 111n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256465
PNG
(US10329256, Example 10 | US9487512, 10 | US9944601...)
Show SMILES C1[C@H](NC2CCCNC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-5-11(6-3-1)13-9-14(13)16-12-7-4-8-15-10-12/h1-3,5-6,12-16H,4,7-10H2/t12?,13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 119n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256476
PNG
(US10329256, Example 21 | US9487512, 21 | US9944601...)
Show SMILES Fc1ccc(cc1F)C1CC1NC1CCNCC1
Show InChI InChI=1/C14H18F2N2/c15-12-2-1-9(7-13(12)16)11-8-14(11)18-10-3-5-17-6-4-10/h1-2,7,10-11,14,17-18H,3-6,8H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 127n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256471
PNG
(US10329256, Example 16 | US9487512, 16 | US9944601...)
Show SMILES C1[C@H](NC2CCNC3CCCCC23)[C@H]1c1ccccc1
Show InChI InChI=1/C18H26N2/c1-2-6-13(7-3-1)15-12-18(15)20-17-10-11-19-16-9-5-4-8-14(16)17/h1-3,6-7,14-20H,4-5,8-12H2/t14?,15-,16?,17?,18+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 139n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256492
PNG
(US10329256, Example 37 | US9487512, 37 | US9944601...)
Show SMILES CN1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C15H22N2/c1-17-9-7-13(8-10-17)16-15-11-14(15)12-5-3-2-4-6-12/h2-6,13-16H,7-11H2,1H3/t14-,15+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 153n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256496
PNG
(US10329256, Example 41 | US9487512, 41 | US9944601...)
Show SMILES Brc1ccc(cc1)[C@H]1C[C@@H]1NC1CCS(=O)(=O)CC1
Show InChI InChI=1/C14H18BrNO2S/c15-11-3-1-10(2-4-11)13-9-14(13)16-12-5-7-19(17,18)8-6-12/h1-4,12-14,16H,5-9H2/t13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 177n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256495
PNG
(US10329256, Example 40 | US9487512, 40 | US9944601...)
Show SMILES C1[C@H](NC2CCN(CC2)c2ccncc2)[C@H]1c1ccccc1
Show InChI InChI=1/C19H23N3/c1-2-4-15(5-3-1)18-14-19(18)21-16-8-12-22(13-9-16)17-6-10-20-11-7-17/h1-7,10-11,16,18-19,21H,8-9,12-14H2/t18-,19+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 188n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256488
PNG
(US10329256, Example 33 | US9487512, 33 | US9944601...)
Show SMILES CC(=O)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(Br)cc1
Show InChI InChI=1/C16H21BrN2O/c1-11(20)19-8-6-14(7-9-19)18-16-10-15(16)12-2-4-13(17)5-3-12/h2-5,14-16,18H,6-10H2,1H3/t15-,16+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 212n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256464
PNG
(US10329256, Example 9 | US9487512, 9 | US9944601, ...)
Show SMILES Clc1ccc(cc1)-c1ccc(cc1)[C@H]1C[C@@H]1NCCC1CCOCC1
Show InChI InChI=1/C22H26ClNO/c23-20-7-5-18(6-8-20)17-1-3-19(4-2-17)21-15-22(21)24-12-9-16-10-13-25-14-11-16/h1-8,16,21-22,24H,9-15H2/t21-,22+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 296n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 491n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256490
PNG
(US10329256, Example 35 | US9487512, 35 | US9944601...)
Show SMILES Brc1ccc(cc1)[C@H]1C[C@@H]1NC1CCOCC1
Show InChI InChI=1/C14H18BrNO/c15-11-3-1-10(2-4-11)13-9-14(13)16-12-5-7-17-8-6-12/h1-4,12-14,16H,5-9H2/t13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 549n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256462
PNG
(US10329256, Example 7 | US9487512, 7 | US9944601, ...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cn1)[C@H]1C[C@@H]1NC1CCOCC1
Show InChI InChI=1/C20H21F3N2O/c21-20(22,23)15-3-1-2-13(10-15)18-5-4-14(12-24-18)17-11-19(17)25-16-6-8-26-9-7-16/h1-5,10,12,16-17,19,25H,6-9,11H2/t17-,19+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 700n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256466
PNG
(US10329256, Example 11 | US9487512, 11 | US9944601...)
Show SMILES C1[C@H](NC2CCNC2)[C@H]1c1ccccc1
Show InChI InChI=1/C13H18N2/c1-2-4-10(5-3-1)12-8-13(12)15-11-6-7-14-9-11/h1-5,11-15H,6-9H2/t11?,12-,13+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 908n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256483
PNG
(US10329256, Example 28 | US9487512, 28 | US9944601...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cc1)[C@H]1C[C@@H]1NCC1CCNCC1
Show InChI InChI=1/C22H25F3N2/c23-22(24,25)19-3-1-2-18(12-19)16-4-6-17(7-5-16)20-13-21(20)27-14-15-8-10-26-11-9-15/h1-7,12,15,20-21,26-27H,8-11,13-14H2/t20-,21+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.02E+3n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256487
PNG
(US10329256, Example 32 | US9487512, 32 | US9944601...)
Show SMILES CS(=O)(=O)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C15H22N2O2S/c1-20(18,19)17-9-7-13(8-10-17)16-15-11-14(15)12-5-3-2-4-6-12/h2-6,13-16H,7-11H2,1H3/t14-,15+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.68E+3n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256467
PNG
(US10329256, Example 12 | US9487512, 12 | US9944601...)
Show SMILES C1[C@H](NC2CNC2)[C@H]1c1ccccc1
Show InChI InChI=1/C12H16N2/c1-2-4-9(5-3-1)11-6-12(11)14-10-7-13-8-10/h1-5,10-14H,6-8H2/t11-,12+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.94E+3n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256463
PNG
(US10329256, Example 8 | US9487512, 8 | US9944601, ...)
Show SMILES C(CC1CCOCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H23NO/c1-2-4-14(5-3-1)15-12-16(15)17-9-6-13-7-10-18-11-8-13/h1-5,13,15-17H,6-12H2/t15-,16+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.18E+3n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM388464
PNG
(US10329256, Example 4 | US9944601, Example 4)
Show SMILES C(Oc1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1)c1ccccc1
Show InChI InChI=1S/C21H26N2O/c1-2-4-16(5-3-1)15-24-19-8-6-17(7-9-19)20-14-21(20)23-18-10-12-22-13-11-18/h1-9,18,20-23H,10-15H2/t20-,21+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.18E+3n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256482
PNG
(US10329256, Example 27 | US9487512, 27 | US9944601...)
Show SMILES Fc1ccccc1COc1ccc(cc1)[C@H]1C[C@@H]1NCC1CCNCC1
Show InChI InChI=1/C22H27FN2O/c23-21-4-2-1-3-18(21)15-26-19-7-5-17(6-8-19)20-13-22(20)25-14-16-9-11-24-12-10-16/h1-8,16,20,22,24-25H,9-15H2/t20-,22+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.58E+3n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256497
PNG
(US10329256, Example 42 | US9487512, 42 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccc(cc1)C1CC1)C1CCNCC1
Show InChI InChI=1/C18H26N2/c1-2-14(1)15-3-5-16(6-4-15)17-11-18(17)20-12-13-7-9-19-10-8-13/h3-6,13-14,17-20H,1-2,7-12H2/t17-,18+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.79E+3n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256494
PNG
(US10329256, Example 39 | US9487512, 39 | US9944601...)
Show SMILES FC(F)(F)CN1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H21F3N2/c17-16(18,19)11-21-8-6-13(7-9-21)20-15-10-14(15)12-4-2-1-3-5-12/h1-5,13-15,20H,6-11H2/t14-,15+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4.50E+3n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256482
PNG
(US10329256, Example 27 | US9487512, 27 | US9944601...)
Show SMILES Fc1ccccc1COc1ccc(cc1)[C@H]1C[C@@H]1NCC1CCNCC1
Show InChI InChI=1/C22H27FN2O/c23-21-4-2-1-3-18(21)15-26-19-7-5-17(6-8-19)20-13-22(20)25-14-16-9-11-24-12-10-16/h1-8,16,20,22,24-25H,9-15H2/t20-,22+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.01E+3n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256464
PNG
(US10329256, Example 9 | US9487512, 9 | US9944601, ...)
Show SMILES Clc1ccc(cc1)-c1ccc(cc1)[C@H]1C[C@@H]1NCCC1CCOCC1
Show InChI InChI=1/C22H26ClNO/c23-20-7-5-18(6-8-20)17-1-3-19(4-2-17)21-15-22(21)24-12-9-16-10-13-25-14-11-16/h1-8,16,21-22,24H,9-15H2/t21-,22+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.60E+3n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256461
PNG
(US10329256, Example 6 | US9487512, 6 | US9944601, ...)
Show SMILES C(CC1CCNCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H24N2/c1-2-4-14(5-3-1)15-12-16(15)18-11-8-13-6-9-17-10-7-13/h1-5,13,15-18H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.01E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256483
PNG
(US10329256, Example 28 | US9487512, 28 | US9944601...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cc1)[C@H]1C[C@@H]1NCC1CCNCC1
Show InChI InChI=1/C22H25F3N2/c23-22(24,25)19-3-1-2-18(12-19)16-4-6-17(7-5-16)20-13-21(20)27-14-15-8-10-26-11-9-15/h1-7,12,15,20-21,26-27H,8-11,13-14H2/t20-,21+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.16E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256464
PNG
(US10329256, Example 9 | US9487512, 9 | US9944601, ...)
Show SMILES Clc1ccc(cc1)-c1ccc(cc1)[C@H]1C[C@@H]1NCCC1CCOCC1
Show InChI InChI=1/C22H26ClNO/c23-20-7-5-18(6-8-20)17-1-3-19(4-2-17)21-15-22(21)24-12-9-16-10-13-25-14-11-16/h1-8,16,21-22,24H,9-15H2/t21-,22+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.46E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256479
PNG
(US10329256, Example 24 | US9487512, 24 | US9944601...)
Show SMILES C1C(NC2CCNCC2)C1c1ccc2ccccc2c1
Show InChI InChI=1/C18H22N2/c1-2-4-14-11-15(6-5-13(14)3-1)17-12-18(17)20-16-7-9-19-10-8-16/h1-6,11,16-20H,7-10,12H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.51E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256496
PNG
(US10329256, Example 41 | US9487512, 41 | US9944601...)
Show SMILES Brc1ccc(cc1)[C@H]1C[C@@H]1NC1CCS(=O)(=O)CC1
Show InChI InChI=1/C14H18BrNO2S/c15-11-3-1-10(2-4-11)13-9-14(13)16-12-5-7-19(17,18)8-6-12/h1-4,12-14,16H,5-9H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.69E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256490
PNG
(US10329256, Example 35 | US9487512, 35 | US9944601...)
Show SMILES Brc1ccc(cc1)[C@H]1C[C@@H]1NC1CCOCC1
Show InChI InChI=1/C14H18BrNO/c15-11-3-1-10(2-4-11)13-9-14(13)16-12-5-7-17-8-6-12/h1-4,12-14,16H,5-9H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.87E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256481
PNG
(US10329256, Example 26 | US9487512, 26 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CCNC1
Show InChI InChI=1/C14H20N2/c1-2-4-12(5-3-1)13-8-14(13)16-10-11-6-7-15-9-11/h1-5,11,13-16H,6-10H2/t11?,13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.08E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256467
PNG
(US10329256, Example 12 | US9487512, 12 | US9944601...)
Show SMILES C1[C@H](NC2CNC2)[C@H]1c1ccccc1
Show InChI InChI=1/C12H16N2/c1-2-4-9(5-3-1)11-6-12(11)14-10-7-13-8-10/h1-5,10-14H,6-8H2/t11-,12+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.38E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256486
PNG
(US10329256, Example 31 | US9487512, 31 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CNC1
Show InChI InChI=1/C13H18N2/c1-2-4-11(5-3-1)12-6-13(12)15-9-10-7-14-8-10/h1-5,10,12-15H,6-9H2/t12-,13+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.55E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256465
PNG
(US10329256, Example 10 | US9487512, 10 | US9944601...)
Show SMILES C1[C@H](NC2CCCNC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-5-11(6-3-1)13-9-14(13)16-12-7-4-8-15-10-12/h1-3,5-6,12-16H,4,7-10H2/t12?,13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.65E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256489
PNG
(US10329256, Example 34 | US9487512, 34 | US9944601...)
Show SMILES NC(=O)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(Br)cc1
Show InChI InChI=1/C15H20BrN3O/c16-11-3-1-10(2-4-11)13-9-14(13)18-12-5-7-19(8-6-12)15(17)20/h1-4,12-14,18H,5-9H2,(H2,17,20)/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.24E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256462
PNG
(US10329256, Example 7 | US9487512, 7 | US9944601, ...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cn1)[C@H]1C[C@@H]1NC1CCOCC1
Show InChI InChI=1/C20H21F3N2O/c21-20(22,23)15-3-1-2-13(10-15)18-5-4-14(12-24-18)17-11-19(17)25-16-6-8-26-9-7-16/h1-5,10,12,16-17,19,25H,6-9,11H2/t17-,19+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.35E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256489
PNG
(US10329256, Example 34 | US9487512, 34 | US9944601...)
Show SMILES NC(=O)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(Br)cc1
Show InChI InChI=1/C15H20BrN3O/c16-11-3-1-10(2-4-11)13-9-14(13)18-12-5-7-19(8-6-12)15(17)20/h1-4,12-14,18H,5-9H2,(H2,17,20)/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.41E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50142189
PNG
(CHEMBL3759239 | US10329256, Example 5 | US9487512,...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CCNCC1
Show InChI InChI=1/C15H22N2/c1-2-4-13(5-3-1)14-10-15(14)17-11-12-6-8-16-9-7-12/h1-5,12,14-17H,6-11H2/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 3.54E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256495
PNG
(US10329256, Example 40 | US9487512, 40 | US9944601...)
Show SMILES C1[C@H](NC2CCN(CC2)c2ccncc2)[C@H]1c1ccccc1
Show InChI InChI=1/C19H23N3/c1-2-4-15(5-3-1)18-14-19(18)21-16-8-12-22(13-9-16)17-6-10-20-11-7-17/h1-7,10-11,16,18-19,21H,8-9,12-14H2/t18-,19+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.60E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256466
PNG
(US10329256, Example 11 | US9487512, 11 | US9944601...)
Show SMILES C1[C@H](NC2CCNC2)[C@H]1c1ccccc1
Show InChI InChI=1/C13H18N2/c1-2-4-10(5-3-1)12-8-13(12)15-11-6-7-14-9-11/h1-5,11-15H,6-9H2/t11?,12-,13+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.77E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256461
PNG
(US10329256, Example 6 | US9487512, 6 | US9944601, ...)
Show SMILES C(CC1CCNCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H24N2/c1-2-4-14(5-3-1)15-12-16(15)18-11-8-13-6-9-17-10-7-13/h1-5,13,15-18H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.83E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM388464
PNG
(US10329256, Example 4 | US9944601, Example 4)
Show SMILES C(Oc1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1)c1ccccc1
Show InChI InChI=1S/C21H26N2O/c1-2-4-16(5-3-1)15-24-19-8-6-17(7-9-19)20-14-21(20)23-18-10-12-22-13-11-18/h1-9,18,20-23H,10-15H2/t20-,21+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.99E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256498
PNG
(US10329256, Example 43 | US9487512, 43 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccc(cc1)-c1cccnc1)C1CCNCC1
Show InChI InChI=1/C20H25N3/c1-2-18(14-22-9-1)16-3-5-17(6-4-16)19-12-20(19)23-13-15-7-10-21-11-8-15/h1-6,9,14-15,19-21,23H,7-8,10-13H2/t19-,20+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4.31E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256490
PNG
(US10329256, Example 35 | US9487512, 35 | US9944601...)
Show SMILES Brc1ccc(cc1)[C@H]1C[C@@H]1NC1CCOCC1
Show InChI InChI=1/C14H18BrNO/c15-11-3-1-10(2-4-11)13-9-14(13)16-12-5-7-17-8-6-12/h1-4,12-14,16H,5-9H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4.54E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256466
PNG
(US10329256, Example 11 | US9487512, 11 | US9944601...)
Show SMILES C1[C@H](NC2CCNC2)[C@H]1c1ccccc1
Show InChI InChI=1/C13H18N2/c1-2-4-10(5-3-1)12-8-13(12)15-11-6-7-14-9-11/h1-5,11-15H,6-9H2/t11?,12-,13+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4.68E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256496
PNG
(US10329256, Example 41 | US9487512, 41 | US9944601...)
Show SMILES Brc1ccc(cc1)[C@H]1C[C@@H]1NC1CCS(=O)(=O)CC1
Show InChI InChI=1/C14H18BrNO2S/c15-11-3-1-10(2-4-11)13-9-14(13)16-12-5-7-19(17,18)8-6-12/h1-4,12-14,16H,5-9H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256469
PNG
(US10329256, Example 14 | US9487512, 14 | US9944601...)
Show SMILES C1[C@H](NC2CCC3(CCNCC3)CC2)[C@H]1c1ccccc1
Show InChI InChI=1/C19H28N2/c1-2-4-15(5-3-1)17-14-18(17)21-16-6-8-19(9-7-16)10-12-20-13-11-19/h1-5,16-18,20-21H,6-14H2/t17-,18+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.43E+4n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256470
PNG
(US10329256, Example 15 | US9487512, 15 | US9944601...)
Show SMILES C1[C@H](NC2CC3(C2)CCNCC3)[C@H]1c1ccccc1
Show InChI InChI=1/C17H24N2/c1-2-4-13(5-3-1)15-10-16(15)19-14-11-17(12-14)6-8-18-9-7-17/h1-5,14-16,18-19H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256471
PNG
(US10329256, Example 16 | US9487512, 16 | US9944601...)
Show SMILES C1[C@H](NC2CCNC3CCCCC23)[C@H]1c1ccccc1
Show InChI InChI=1/C18H26N2/c1-2-6-13(7-3-1)15-12-18(15)20-17-10-11-19-16-9-5-4-8-14(16)17/h1-3,6-7,14-20H,4-5,8-12H2/t14?,15-,16?,17?,18+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256472
PNG
(US10329256, Example 17 | US9487512, 17 | US9944601...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1cccnc1
Show InChI InChI=1/C13H19N3/c1-2-10(9-15-5-1)12-8-13(12)16-11-3-6-14-7-4-11/h1-2,5,9,11-14,16H,3-4,6-8H2/t12-,13+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256475
PNG
(US10329256, Example 20 | US9487512, 20 | US9944601...)
Show SMILES Fc1ccccc1C1CC1NC1CCNCC1
Show InChI InChI=1/C14H19FN2/c15-13-4-2-1-3-11(13)12-9-14(12)17-10-5-7-16-8-6-10/h1-4,10,12,14,16-17H,5-9H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256476
PNG
(US10329256, Example 21 | US9487512, 21 | US9944601...)
Show SMILES Fc1ccc(cc1F)C1CC1NC1CCNCC1
Show InChI InChI=1/C14H18F2N2/c15-12-2-1-9(7-13(12)16)11-8-14(11)18-10-3-5-17-6-4-10/h1-2,7,10-11,14,17-18H,3-6,8H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256485
PNG
(US10329256, Example 30 | US9487512, 30 | US9944601...)
Show SMILES CC(C)S(=O)(=O)Nc1cccc(c1)-c1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1
Show InChI InChI=1/C23H31N3O2S/c1-16(2)29(27,28)26-21-5-3-4-19(14-21)17-6-8-18(9-7-17)22-15-23(22)25-20-10-12-24-13-11-20/h3-9,14,16,20,22-26H,10-13,15H2,1-2H3/t22-,23+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256459
PNG
(US10329256, Example 3 | US9487512, 3 | US9944601, ...)
Show SMILES C1[C@@H](NC2CCNCC2)[C@@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM50142189
PNG
(CHEMBL3759239 | US10329256, Example 5 | US9487512,...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CCNCC1
Show InChI InChI=1/C15H22N2/c1-2-4-13(5-3-1)14-10-15(14)17-11-12-6-8-16-9-7-12/h1-5,12,14-17H,6-11H2/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256468
PNG
(US10329256, Example 13 | US9487512, 13 | US9944601...)
Show SMILES C1[C@H](NC2CC3CCC(C2)N3)[C@H]1c1ccccc1
Show InChI InChI=1/C16H22N2/c1-2-4-11(5-3-1)15-10-16(15)18-14-8-12-6-7-13(9-14)17-12/h1-5,12-18H,6-10H2/t12?,13?,14?,15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256473
PNG
(US10329256, Example 18 | US9487512, 18 | US9944601...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1cncs1
Show InChI InChI=1/C11H17N3S/c1-3-12-4-2-8(1)14-10-5-9(10)11-6-13-7-15-11/h6-10,12,14H,1-5H2/t9-,10-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256474
PNG
(US10329256, Example 19 | US9487512, 19 | US9944601...)
Show SMILES Cc1ccccc1C1CC1NC1CCNCC1
Show InChI InChI=1/C15H22N2/c1-11-4-2-3-5-13(11)14-10-15(14)17-12-6-8-16-9-7-12/h2-5,12,14-17H,6-10H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256491
PNG
(US10329256, Example 36 | US9487512, 36 | US9944601...)
Show SMILES CC1(C)CC(CC(C)(C)N1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C18H28N2/c1-17(2)11-14(12-18(3,4)20-17)19-16-10-15(16)13-8-6-5-7-9-13/h5-9,14-16,19-20H,10-12H2,1-4H3/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256494
PNG
(US10329256, Example 39 | US9487512, 39 | US9944601...)
Show SMILES FC(F)(F)CN1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H21F3N2/c17-16(18,19)11-21-8-6-13(7-9-21)20-15-10-14(15)12-4-2-1-3-5-12/h1-5,13-15,20H,6-11H2/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256475
PNG
(US10329256, Example 20 | US9487512, 20 | US9944601...)
Show SMILES Fc1ccccc1C1CC1NC1CCNCC1
Show InChI InChI=1/C14H19FN2/c15-13-4-2-1-3-11(13)12-9-14(12)17-10-5-7-16-8-6-10/h1-4,10,12,14,16-17H,5-9H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256478
PNG
(US10329256, Example 23 | US9487512, 23 | US9944601...)
Show SMILES Oc1ccc(cc1)C1CC1NC1CCNCC1
Show InChI InChI=1/C14H20N2O/c17-12-3-1-10(2-4-12)13-9-14(13)16-11-5-7-15-8-6-11/h1-4,11,13-17H,5-9H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256492
PNG
(US10329256, Example 37 | US9487512, 37 | US9944601...)
Show SMILES CN1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C15H22N2/c1-17-9-7-13(8-10-17)16-15-11-14(15)12-5-3-2-4-6-12/h2-6,13-16H,7-11H2,1H3/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256494
PNG
(US10329256, Example 39 | US9487512, 39 | US9944601...)
Show SMILES FC(F)(F)CN1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H21F3N2/c17-16(18,19)11-21-8-6-13(7-9-21)20-15-10-14(15)12-4-2-1-3-5-12/h1-5,13-15,20H,6-11H2/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256495
PNG
(US10329256, Example 40 | US9487512, 40 | US9944601...)
Show SMILES C1[C@H](NC2CCN(CC2)c2ccncc2)[C@H]1c1ccccc1
Show InChI InChI=1/C19H23N3/c1-2-4-15(5-3-1)18-14-19(18)21-16-8-12-22(13-9-16)17-6-10-20-11-7-17/h1-7,10-11,16,18-19,21H,8-9,12-14H2/t18-,19+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256465
PNG
(US10329256, Example 10 | US9487512, 10 | US9944601...)
Show SMILES C1[C@H](NC2CCCNC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-5-11(6-3-1)13-9-14(13)16-12-7-4-8-15-10-12/h1-3,5-6,12-16H,4,7-10H2/t12?,13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256485
PNG
(US10329256, Example 30 | US9487512, 30 | US9944601...)
Show SMILES CC(C)S(=O)(=O)Nc1cccc(c1)-c1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1
Show InChI InChI=1/C23H31N3O2S/c1-16(2)29(27,28)26-21-5-3-4-19(14-21)17-6-8-18(9-7-17)22-15-23(22)25-20-10-12-24-13-11-20/h3-9,14,16,20,22-26H,10-13,15H2,1-2H3/t22-,23+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256486
PNG
(US10329256, Example 31 | US9487512, 31 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CNC1
Show InChI InChI=1/C13H18N2/c1-2-4-11(5-3-1)12-6-13(12)15-9-10-7-14-8-10/h1-5,10,12-15H,6-9H2/t12-,13+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256487
PNG
(US10329256, Example 32 | US9487512, 32 | US9944601...)
Show SMILES CS(=O)(=O)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C15H22N2O2S/c1-20(18,19)17-9-7-13(8-10-17)16-15-11-14(15)12-5-3-2-4-6-12/h2-6,13-16H,7-11H2,1H3/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256493
PNG
(US10329256, Example 38 | US9487512, 38 | US9944601...)
Show SMILES CC(C)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C17H26N2/c1-13(2)19-10-8-15(9-11-19)18-17-12-16(17)14-6-4-3-5-7-14/h3-7,13,15-18H,8-12H2,1-2H3/t16-,17+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256463
PNG
(US10329256, Example 8 | US9487512, 8 | US9944601, ...)
Show SMILES C(CC1CCOCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H23NO/c1-2-4-14(5-3-1)15-12-16(15)17-9-6-13-7-10-18-11-8-13/h1-5,13,15-17H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256468
PNG
(US10329256, Example 13 | US9487512, 13 | US9944601...)
Show SMILES C1[C@H](NC2CC3CCC(C2)N3)[C@H]1c1ccccc1
Show InChI InChI=1/C16H22N2/c1-2-4-11(5-3-1)15-10-16(15)18-14-8-12-6-7-13(9-14)17-12/h1-5,12-18H,6-10H2/t12?,13?,14?,15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256474
PNG
(US10329256, Example 19 | US9487512, 19 | US9944601...)
Show SMILES Cc1ccccc1C1CC1NC1CCNCC1
Show InChI InChI=1/C15H22N2/c1-11-4-2-3-5-13(11)14-10-15(14)17-12-6-8-16-9-7-12/h2-5,12,14-17H,6-10H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256478
PNG
(US10329256, Example 23 | US9487512, 23 | US9944601...)
Show SMILES Oc1ccc(cc1)C1CC1NC1CCNCC1
Show InChI InChI=1/C14H20N2O/c17-12-3-1-10(2-4-12)13-9-14(13)16-11-5-7-15-8-6-11/h1-4,11,13-17H,5-9H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256480
PNG
(US10329256, Example 25 | US9487512, 25 | US9944601...)
Show SMILES CC1(CC1NC1CCNCC1)c1ccccc1
Show InChI InChI=1/C15H22N2/c1-15(12-5-3-2-4-6-12)11-14(15)17-13-7-9-16-10-8-13/h2-6,13-14,16-17H,7-11H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256459
PNG
(US10329256, Example 3 | US9487512, 3 | US9944601, ...)
Show SMILES C1[C@@H](NC2CCNCC2)[C@@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256481
PNG
(US10329256, Example 26 | US9487512, 26 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CCNC1
Show InChI InChI=1/C14H20N2/c1-2-4-12(5-3-1)13-8-14(13)16-10-11-6-7-15-9-11/h1-5,11,13-16H,6-10H2/t11?,13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256463
PNG
(US10329256, Example 8 | US9487512, 8 | US9944601, ...)
Show SMILES C(CC1CCOCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H23NO/c1-2-4-14(5-3-1)15-12-16(15)17-9-6-13-7-10-18-11-8-13/h1-5,13,15-17H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256487
PNG
(US10329256, Example 32 | US9487512, 32 | US9944601...)
Show SMILES CS(=O)(=O)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C15H22N2O2S/c1-20(18,19)17-9-7-13(8-10-17)16-15-11-14(15)12-5-3-2-4-6-12/h2-6,13-16H,7-11H2,1H3/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256491
PNG
(US10329256, Example 36 | US9487512, 36 | US9944601...)
Show SMILES CC1(C)CC(CC(C)(C)N1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C18H28N2/c1-17(2)11-14(12-18(3,4)20-17)19-16-10-15(16)13-8-6-5-7-9-13/h5-9,14-16,19-20H,10-12H2,1-4H3/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256493
PNG
(US10329256, Example 38 | US9487512, 38 | US9944601...)
Show SMILES CC(C)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C17H26N2/c1-13(2)19-10-8-15(9-11-19)18-17-12-16(17)14-6-4-3-5-7-14/h3-7,13,15-18H,8-12H2,1-2H3/t16-,17+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256499
PNG
(US10329256, Example 44 | US9487512, 44 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccc(cc1)-c1ccn[nH]1)C1CCNCC1
Show InChI InChI=1/C18H24N4/c1-3-15(17-7-10-21-22-17)4-2-14(1)16-11-18(16)20-12-13-5-8-19-9-6-13/h1-4,7,10,13,16,18-20H,5-6,8-9,11-12H2,(H,21,22)/t16-,18+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256469
PNG
(US10329256, Example 14 | US9487512, 14 | US9944601...)
Show SMILES C1[C@H](NC2CCC3(CCNCC3)CC2)[C@H]1c1ccccc1
Show InChI InChI=1/C19H28N2/c1-2-4-15(5-3-1)17-14-18(17)21-16-6-8-19(9-7-16)10-12-20-13-11-19/h1-5,16-18,20-21H,6-14H2/t17-,18+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256471
PNG
(US10329256, Example 16 | US9487512, 16 | US9944601...)
Show SMILES C1[C@H](NC2CCNC3CCCCC23)[C@H]1c1ccccc1
Show InChI InChI=1/C18H26N2/c1-2-6-13(7-3-1)15-12-18(15)20-17-10-11-19-16-9-5-4-8-14(16)17/h1-3,6-7,14-20H,4-5,8-12H2/t14?,15-,16?,17?,18+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256472
PNG
(US10329256, Example 17 | US9487512, 17 | US9944601...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1cccnc1
Show InChI InChI=1/C13H19N3/c1-2-10(9-15-5-1)12-8-13(12)16-11-3-6-14-7-4-11/h1-2,5,9,11-14,16H,3-4,6-8H2/t12-,13+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256473
PNG
(US10329256, Example 18 | US9487512, 18 | US9944601...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1cncs1
Show InChI InChI=1/C11H17N3S/c1-3-12-4-2-8(1)14-10-5-9(10)11-6-13-7-15-11/h6-10,12,14H,1-5H2/t9-,10-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256492
PNG
(US10329256, Example 37 | US9487512, 37 | US9944601...)
Show SMILES CN1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C15H22N2/c1-17-9-7-13(8-10-17)16-15-11-14(15)12-5-3-2-4-6-12/h2-6,13-16H,7-11H2,1H3/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256467
PNG
(US10329256, Example 12 | US9487512, 12 | US9944601...)
Show SMILES C1[C@H](NC2CNC2)[C@H]1c1ccccc1
Show InChI InChI=1/C12H16N2/c1-2-4-9(5-3-1)11-6-12(11)14-10-7-13-8-10/h1-5,10-14H,6-8H2/t11-,12+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256497
PNG
(US10329256, Example 42 | US9487512, 42 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccc(cc1)C1CC1)C1CCNCC1
Show InChI InChI=1/C18H26N2/c1-2-14(1)15-3-5-16(6-4-15)17-11-18(17)20-12-13-7-9-19-10-8-13/h3-6,13-14,17-20H,1-2,7-12H2/t17-,18+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256484
PNG
(US10329256, Example 29 | US9487512, 29 | US9944601...)
Show SMILES COc1ccc(NS(C)(=O)=O)cc1-c1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1
Show InChI InChI=1/C22H29N3O3S/c1-28-22-8-7-18(25-29(2,26)27)13-20(22)16-5-3-15(4-6-16)19-14-21(19)24-17-9-11-23-12-10-17/h3-8,13,17,19,21,23-25H,9-12,14H2,1-2H3/t19-,21+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256470
PNG
(US10329256, Example 15 | US9487512, 15 | US9944601...)
Show SMILES C1[C@H](NC2CC3(C2)CCNCC3)[C@H]1c1ccccc1
Show InChI InChI=1/C17H24N2/c1-2-4-13(5-3-1)15-10-16(15)19-14-11-17(12-14)6-8-18-9-7-17/h1-5,14-16,18-19H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256477
PNG
(US10329256, Example 22 | US9487512, 22 | US9944601...)
Show SMILES COc1ccc(cc1)C1CC1NC1CCNCC1
Show InChI InChI=1/C15H22N2O/c1-18-13-4-2-11(3-5-13)14-10-15(14)17-12-6-8-16-9-7-12/h2-5,12,14-17H,6-10H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256480
PNG
(US10329256, Example 25 | US9487512, 25 | US9944601...)
Show SMILES CC1(CC1NC1CCNCC1)c1ccccc1
Show InChI InChI=1/C15H22N2/c1-15(12-5-3-2-4-6-12)11-14(15)17-13-7-9-16-10-8-13/h2-6,13-14,16-17H,7-11H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256484
PNG
(US10329256, Example 29 | US9487512, 29 | US9944601...)
Show SMILES COc1ccc(NS(C)(=O)=O)cc1-c1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1
Show InChI InChI=1/C22H29N3O3S/c1-28-22-8-7-18(25-29(2,26)27)13-20(22)16-5-3-15(4-6-16)19-14-21(19)24-17-9-11-23-12-10-17/h3-8,13,17,19,21,23-25H,9-12,14H2,1-2H3/t19-,21+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256488
PNG
(US10329256, Example 33 | US9487512, 33 | US9944601...)
Show SMILES CC(=O)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(Br)cc1
Show InChI InChI=1/C16H21BrN2O/c1-11(20)19-8-6-14(7-9-19)18-16-10-15(16)12-2-4-13(17)5-3-12/h2-5,14-16,18H,6-10H2,1H3/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256478
PNG
(US10329256, Example 23 | US9487512, 23 | US9944601...)
Show SMILES Oc1ccc(cc1)C1CC1NC1CCNCC1
Show InChI InChI=1/C14H20N2O/c17-12-3-1-10(2-4-12)13-9-14(13)16-11-5-7-15-8-6-11/h1-4,11,13-17H,5-9H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256498
PNG
(US10329256, Example 43 | US9487512, 43 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccc(cc1)-c1cccnc1)C1CCNCC1
Show InChI InChI=1/C20H25N3/c1-2-18(14-22-9-1)16-3-5-17(6-4-16)19-12-20(19)23-13-15-7-10-21-11-8-15/h1-6,9,14-15,19-21,23H,7-8,10-13H2/t19-,20+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256476
PNG
(US10329256, Example 21 | US9487512, 21 | US9944601...)
Show SMILES Fc1ccc(cc1F)C1CC1NC1CCNCC1
Show InChI InChI=1/C14H18F2N2/c15-12-2-1-9(7-13(12)16)11-8-14(11)18-10-3-5-17-6-4-10/h1-2,7,10-11,14,17-18H,3-6,8H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256488
PNG
(US10329256, Example 33 | US9487512, 33 | US9944601...)
Show SMILES CC(=O)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(Br)cc1
Show InChI InChI=1/C16H21BrN2O/c1-11(20)19-8-6-14(7-9-19)18-16-10-15(16)12-2-4-13(17)5-3-12/h2-5,14-16,18H,6-10H2,1H3/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256477
PNG
(US10329256, Example 22 | US9487512, 22 | US9944601...)
Show SMILES COc1ccc(cc1)C1CC1NC1CCNCC1
Show InChI InChI=1/C15H22N2O/c1-18-13-4-2-11(3-5-13)14-10-15(14)17-12-6-8-16-9-7-12/h2-5,12,14-17H,6-10H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256479
PNG
(US10329256, Example 24 | US9487512, 24 | US9944601...)
Show SMILES C1C(NC2CCNCC2)C1c1ccc2ccccc2c1
Show InChI InChI=1/C18H22N2/c1-2-4-14-11-15(6-5-13(14)3-1)17-12-18(17)20-16-7-9-19-10-8-16/h1-6,11,16-20H,7-10,12H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256499
PNG
(US10329256, Example 44 | US9487512, 44 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccc(cc1)-c1ccn[nH]1)C1CCNCC1
Show InChI InChI=1/C18H24N4/c1-3-15(17-7-10-21-22-17)4-2-14(1)16-11-18(16)20-12-13-5-8-19-9-6-13/h1-4,7,10,13,16,18-20H,5-6,8-9,11-12H2,(H,21,22)/t16-,18+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



ORYZON GENOMICS, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US9944601 (2018)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%