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Patent code US9963434

Compile Data Set for Download or QSAR

Found 220 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393276
PNG
(5-(3,4- difluorobenzenesulfon- amidomethyl)-6- met...)
Show SMILES Cc1ncc(CNC(=O)c2cnc(CNS(=O)(=O)c3ccc(F)c(F)c3)c(C)n2)s1
Show InChI InChI=1S/C18H17F2N5O3S2/c1-10-16(9-24-30(27,28)13-3-4-14(19)15(20)5-13)22-8-17(25-10)18(26)23-7-12-6-21-11(2)29-12/h3-6,8,24H,7,9H2,1-2H3,(H,23,26)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 16.2n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393246
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-6...)
Show SMILES Cc1ncc(CNC(=O)c2cnc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)c(C)n2)s1
Show InChI InChI=1S/C18H17ClFN5O3S2/c1-10-16(9-24-30(27,28)13-3-4-15(20)14(19)5-13)22-8-17(25-10)18(26)23-7-12-6-21-11(2)29-12/h3-6,8,24H,7,9H2,1-2H3,(H,23,26)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 19.6n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393274
PNG
(5-(3- chlorobenzenesulfon- midomethyl)-6- methyl-N...)
Show SMILES Cc1ncc(CNC(=O)c2cnc(CNS(=O)(=O)c3cccc(Cl)c3)c(C)n2)s1
Show InChI InChI=1S/C18H18ClN5O3S2/c1-11-16(10-23-29(26,27)15-5-3-4-13(19)6-15)21-9-17(24-11)18(25)22-8-14-7-20-12(2)28-14/h3-7,9,23H,8,10H2,1-2H3,(H,22,25)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 39.5n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393080
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Cc1ncc(CNC(=O)c2cnc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)cn2)s1
Show InChI InChI=1S/C17H15ClFN5O3S2/c1-10-20-7-12(28-10)8-23-17(25)16-9-21-11(5-22-16)6-24-29(26,27)13-2-3-15(19)14(18)4-13/h2-5,7,9,24H,6,8H2,1H3,(H,23,25)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 61n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393273
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-6...)
Show SMILES CCc1nc(cnc1CNS(=O)(=O)c1ccc(F)c(Cl)c1)C(=O)NCc1cnc(C)s1
Show InChI InChI=1S/C19H19ClFN5O3S2/c1-3-16-17(10-25-31(28,29)13-4-5-15(21)14(20)6-13)23-9-18(26-16)19(27)24-8-12-7-22-11(2)30-12/h4-7,9,25H,3,8,10H2,1-2H3,(H,24,27)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 87.8n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393074
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Cc1ccncc1CNC(=O)c1cnc(CNS(=O)(=O)c2ccc(F)c(Cl)c2)cn1
Show InChI InChI=1S/C19H17ClFN5O3S/c1-12-4-5-22-7-13(12)8-25-19(27)18-11-23-14(9-24-18)10-26-30(28,29)15-2-3-17(21)16(20)6-15/h2-7,9,11,26H,8,10H2,1H3,(H,25,27)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 108n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393097
PNG
(6-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Cn1ccnc1CNC(=O)c1ccc(CNS(=O)(=O)c2ccc(F)c(Cl)c2)nc1
Show InChI InChI=1S/C18H17ClFN5O3S/c1-25-7-6-21-17(25)11-23-18(26)12-2-3-13(22-9-12)10-24-29(27,28)14-4-5-16(20)15(19)8-14/h2-9,24H,10-11H2,1H3,(H,23,26)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 108n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393275
PNG
(5-(4- fluorobenzenesulfon- amidomethyl)-6- methyl-...)
Show SMILES Cc1ncc(CNC(=O)c2cnc(CNS(=O)(=O)c3ccc(F)cc3)c(C)n2)s1
Show InChI InChI=1S/C18H18FN5O3S2/c1-11-16(10-23-29(26,27)15-5-3-13(19)4-6-15)21-9-17(24-11)18(25)22-8-14-7-20-12(2)28-14/h3-7,9,23H,8,10H2,1-2H3,(H,22,25)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 137n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393277
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Cc1ncc(CNC(=O)c2cnc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)c(n2)C(F)(F)F)s1
Show InChI InChI=1S/C18H14ClF4N5O3S2/c1-9-24-5-10(32-9)6-26-17(29)15-7-25-14(16(28-15)18(21,22)23)8-27-33(30,31)11-2-3-13(20)12(19)4-11/h2-5,7,27H,6,8H2,1H3,(H,26,29)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 169n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393194
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES CC(NC(=O)c1cnc(CNS(=O)(=O)c2ccc(F)c(Cl)c2)cn1)c1cnc(C)s1
Show InChI InChI=1S/C18H17ClFN5O3S2/c1-10(17-9-21-11(2)29-17)25-18(26)16-8-22-12(6-23-16)7-24-30(27,28)13-3-4-15(20)14(19)5-13/h3-6,8-10,24H,7H2,1-2H3,(H,25,26)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 180n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393059
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Cc1ccncc1CNC(=O)c1ccc(CNS(=O)(=O)c2ccc(F)c(Cl)c2)cn1
Show InChI InChI=1S/C20H18ClFN4O3S/c1-13-6-7-23-11-15(13)12-25-20(27)19-5-2-14(9-24-19)10-26-30(28,29)16-3-4-18(22)17(21)8-16/h2-9,11,26H,10,12H2,1H3,(H,25,27)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 187n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393066
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Cc1ncc(CNC(=O)c2ccc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)cn2)s1
Show InChI InChI=1S/C18H16ClFN4O3S2/c1-11-21-9-13(28-11)10-23-18(25)17-5-2-12(7-22-17)8-24-29(26,27)14-3-4-16(20)15(19)6-14/h2-7,9,24H,8,10H2,1H3,(H,23,25)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 204n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393226
PNG
(5-(3,4- difluorobenzenesulfon- amidomethyl)-N-[(2-...)
Show SMILES Cc1ncc(CNC(=O)c2ccc(CNS(=O)(=O)c3ccc(F)c(F)c3)cn2)s1
Show InChI InChI=1S/C18H16F2N4O3S2/c1-11-21-9-13(28-11)10-23-18(25)17-5-2-12(7-22-17)8-24-29(26,27)14-3-4-15(19)16(20)6-14/h2-7,9,24H,8,10H2,1H3,(H,23,25)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 219n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393206
PNG
(5-(3,4- difluorobenzenesulfon- amidomethyl)-N-[(2-...)
Show SMILES Cc1ncc(CNC(=O)c2cnc(CNS(=O)(=O)c3ccc(F)c(F)c3)cn2)s1
Show InChI InChI=1S/C17H15F2N5O3S2/c1-10-20-7-12(28-10)8-23-17(25)16-9-21-11(5-22-16)6-24-29(26,27)13-2-3-14(18)15(19)4-13/h2-5,7,9,24H,6,8H2,1H3,(H,23,25)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 313n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393058
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Fc1ccc(cc1Cl)S(=O)(=O)NCc1ccc(nc1)C(=O)NCc1cncs1
Show InChI InChI=1S/C17H14ClFN4O3S2/c18-14-5-13(2-3-15(14)19)28(25,26)23-7-11-1-4-16(21-6-11)17(24)22-9-12-8-20-10-27-12/h1-6,8,10,23H,7,9H2,(H,22,24)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 347n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393268
PNG
(5-(3,5- difluorobenzenesulfon- amidomethyl)-6- met...)
Show SMILES Cc1ncc(CNC(=O)c2cnc(CNS(=O)(=O)c3cc(F)cc(F)c3)c(C)n2)s1
Show InChI InChI=1S/C18H17F2N5O3S2/c1-10-16(9-24-30(27,28)15-4-12(19)3-13(20)5-15)22-8-17(25-10)18(26)23-7-14-6-21-11(2)29-14/h3-6,8,24H,7,9H2,1-2H3,(H,23,26)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 366n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393101
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Fc1ccc(cc1Cl)S(=O)(=O)NCc1cnc(cn1)C(=O)NCc1cccnc1
Show InChI InChI=1S/C18H15ClFN5O3S/c19-15-6-14(3-4-16(15)20)29(27,28)25-10-13-9-23-17(11-22-13)18(26)24-8-12-2-1-5-21-7-12/h1-7,9,11,25H,8,10H2,(H,24,26)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 439n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393266
PNG
(5-(3,4- dichlorobenzenesulfon- amidomethyl)-6- met...)
Show SMILES Cc1ncc(CNC(=O)c2cnc(CNS(=O)(=O)c3ccc(Cl)c(Cl)c3)c(C)n2)s1
Show InChI InChI=1S/C18H17Cl2N5O3S2/c1-10-16(9-24-30(27,28)13-3-4-14(19)15(20)5-13)22-8-17(25-10)18(26)23-7-12-6-21-11(2)29-12/h3-6,8,24H,7,9H2,1-2H3,(H,23,26)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 494n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393188
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Cc1nnc(CNC(=O)c2cnc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)cn2)s1
Show InChI InChI=1S/C16H14ClFN6O3S2/c1-9-23-24-15(28-9)8-21-16(25)14-7-19-10(5-20-14)6-22-29(26,27)11-2-3-13(18)12(17)4-11/h2-5,7,22H,6,8H2,1H3,(H,21,25)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 624n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393096
PNG
(6-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Cc1cnc(CNC(=O)c2ccc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)nc2)cn1
Show InChI InChI=1S/C19H17ClFN5O3S/c1-12-7-23-15(9-22-12)10-25-19(27)13-2-3-14(24-8-13)11-26-30(28,29)16-4-5-18(21)17(20)6-16/h2-9,26H,10-11H2,1H3,(H,25,27)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 630n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393106
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Cc1ccc(CNC(=O)c2cnc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)cn2)n1C
Show InChI InChI=1S/C19H19ClFN5O3S/c1-12-3-4-14(26(12)2)10-24-19(27)18-11-22-13(8-23-18)9-25-30(28,29)15-5-6-17(21)16(20)7-15/h3-8,11,25H,9-10H2,1-2H3,(H,24,27)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 757n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393063
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Fc1ccc(cc1Cl)S(=O)(=O)NCc1ccc(nc1)C(=O)NCc1cccnc1
Show InChI InChI=1S/C19H16ClFN4O3S/c20-16-8-15(4-5-17(16)21)29(27,28)25-12-14-3-6-18(23-10-14)19(26)24-11-13-2-1-7-22-9-13/h1-10,25H,11-12H2,(H,24,26)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 758n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393095
PNG
(6-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Fc1ccc(cc1Cl)S(=O)(=O)NCc1ccc(cn1)C(=O)NCc1cnccn1
Show InChI InChI=1S/C18H15ClFN5O3S/c19-16-7-15(3-4-17(16)20)29(27,28)25-11-13-2-1-12(8-23-13)18(26)24-10-14-9-21-5-6-22-14/h1-9,25H,10-11H2,(H,24,26)
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PC cid
PC sid
UniChem
US Patent
n/an/a 790n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393239
PNG
(5-(3- chlorobenzenesulfon- amidomethyl)-N-[(2- met...)
Show SMILES Cc1ncc(CNC(=O)c2cnc(CNS(=O)(=O)c3cccc(Cl)c3)cn2)s1
Show InChI InChI=1S/C17H16ClN5O3S2/c1-11-19-8-14(27-11)9-22-17(24)16-10-20-13(6-21-16)7-23-28(25,26)15-4-2-3-12(18)5-15/h2-6,8,10,23H,7,9H2,1H3,(H,22,24)
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PC sid
UniChem
US Patent
n/an/a 839n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393183
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES COc1cc(CNC(=O)c2cnc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)cn2)ccn1
Show InChI InChI=1S/C19H17ClFN5O4S/c1-30-18-6-12(4-5-22-18)8-25-19(27)17-11-23-13(9-24-17)10-26-31(28,29)14-2-3-16(21)15(20)7-14/h2-7,9,11,26H,8,10H2,1H3,(H,25,27)
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PC cid
PC sid
UniChem
US Patent
n/an/a 850n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393061
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Fc1ccc(cc1Cl)S(=O)(=O)NCc1cnc(cn1)C(=O)NCc1cncs1
Show InChI InChI=1S/C16H13ClFN5O3S2/c17-13-3-12(1-2-14(13)18)28(25,26)23-5-10-4-21-15(8-20-10)16(24)22-7-11-6-19-9-27-11/h1-4,6,8-9,23H,5,7H2,(H,22,24)
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PC cid
PC sid
UniChem
US Patent
n/an/a 929n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393271
PNG
(5-(4-chloro-3- fluorobenzenesulfon- amidomethyl)-6...)
Show SMILES Cc1ncc(CNC(=O)c2cnc(CNS(=O)(=O)c3ccc(Cl)c(F)c3)c(C)n2)s1
Show InChI InChI=1S/C18H17ClFN5O3S2/c1-10-16(9-24-30(27,28)13-3-4-14(19)15(20)5-13)22-8-17(25-10)18(26)23-7-12-6-21-11(2)29-12/h3-6,8,24H,7,9H2,1-2H3,(H,23,26)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.02E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393176
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Cc1nnc(CNC(=O)c2ccc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)cn2)s1
Show InChI InChI=1S/C17H15ClFN5O3S2/c1-10-23-24-16(28-10)9-21-17(25)15-5-2-11(7-20-15)8-22-29(26,27)12-3-4-14(19)13(18)6-12/h2-7,22H,8-9H2,1H3,(H,21,25)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.02E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393203
PNG
(5-(3- chlorobenzenesulfon- amidomethyl)-N-[(2- met...)
Show SMILES Cc1ncc(CNC(=O)c2ccc(CNS(=O)(=O)c3cccc(Cl)c3)cn2)s1
Show InChI InChI=1S/C18H17ClN4O3S2/c1-12-20-10-15(27-12)11-22-18(24)17-6-5-13(8-21-17)9-23-28(25,26)16-4-2-3-14(19)7-16/h2-8,10,23H,9,11H2,1H3,(H,22,24)
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PC cid
PC sid
UniChem
US Patent
n/an/a 1.04E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393204
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Fc1cncc(CNC(=O)c2cnc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)cn2)c1
Show InChI InChI=1S/C18H14ClF2N5O3S/c19-15-4-14(1-2-16(15)21)30(28,29)26-9-13-8-24-17(10-23-13)18(27)25-6-11-3-12(20)7-22-5-11/h1-5,7-8,10,26H,6,9H2,(H,25,27)
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PC cid
PC sid
UniChem
US Patent
n/an/a 1.10E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393123
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Cc1cnc(CNC(=O)c2cnc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)cn2)cn1
Show InChI InChI=1S/C18H16ClFN6O3S/c1-11-5-22-12(6-21-11)8-25-18(27)17-10-23-13(7-24-17)9-26-30(28,29)14-2-3-16(20)15(19)4-14/h2-7,10,26H,8-9H2,1H3,(H,25,27)
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PC cid
PC sid
UniChem
US Patent
n/an/a 1.25E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393136
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Fc1ccc(cc1Cl)S(=O)(=O)NCc1ccc(nc1)C(=O)NCc1cnccn1
Show InChI InChI=1S/C18H15ClFN5O3S/c19-15-7-14(2-3-16(15)20)29(27,28)25-9-12-1-4-17(23-8-12)18(26)24-11-13-10-21-5-6-22-13/h1-8,10,25H,9,11H2,(H,24,26)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.69E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393103
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Fc1ccc(cc1Cl)S(=O)(=O)NCc1cnc(cn1)C(=O)NCc1ccncc1
Show InChI InChI=1S/C18H15ClFN5O3S/c19-15-7-14(1-2-16(15)20)29(27,28)25-10-13-9-23-17(11-22-13)18(26)24-8-12-3-5-21-6-4-12/h1-7,9,11,25H,8,10H2,(H,24,26)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.70E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393083
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Fc1ccc(cc1Cl)S(=O)(=O)NCc1ccc(nc1)C(=O)NCc1cnco1
Show InChI InChI=1S/C17H14ClFN4O4S/c18-14-5-13(2-3-15(14)19)28(25,26)23-7-11-1-4-16(21-6-11)17(24)22-9-12-8-20-10-27-12/h1-6,8,10,23H,7,9H2,(H,22,24)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.95E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393143
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES COc1ccc(CNC(=O)c2ccc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)cn2)cn1
Show InChI InChI=1S/C20H18ClFN4O4S/c1-30-19-7-3-13(10-24-19)11-25-20(27)18-6-2-14(9-23-18)12-26-31(28,29)15-4-5-17(22)16(21)8-15/h2-10,26H,11-12H2,1H3,(H,25,27)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.00E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393104
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Fc1ccc(cc1Cl)S(=O)(=O)NCc1cnc(cn1)C(=O)NCc1cnccn1
Show InChI InChI=1S/C17H14ClFN6O3S/c18-14-5-13(1-2-15(14)19)29(27,28)25-9-12-7-23-16(10-22-12)17(26)24-8-11-6-20-3-4-21-11/h1-7,10,25H,8-9H2,(H,24,26)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.10E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393192
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Fc1ccc(cc1Cl)S(=O)(=O)NCc1ccc(nc1)C(=O)NCc1ccno1
Show InChI InChI=1S/C17H14ClFN4O4S/c18-14-7-13(2-3-15(14)19)28(25,26)23-9-11-1-4-16(20-8-11)17(24)21-10-12-5-6-22-27-12/h1-8,23H,9-10H2,(H,21,24)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.18E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393098
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES CC(NC(=O)c1ccc(CNS(=O)(=O)c2ccc(F)c(Cl)c2)cn1)c1cccs1
Show InChI InChI=1S/C19H17ClFN3O3S2/c1-12(18-3-2-8-28-18)24-19(25)17-7-4-13(10-22-17)11-23-29(26,27)14-5-6-16(21)15(20)9-14/h2-10,12,23H,11H2,1H3,(H,24,25)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.40E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393187
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Cc1nnc(CNC(=O)c2cnc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)cn2)o1
Show InChI InChI=1S/C16H14ClFN6O4S/c1-9-23-24-15(28-9)8-21-16(25)14-7-19-10(5-20-14)6-22-29(26,27)11-2-3-13(18)12(17)4-11/h2-5,7,22H,6,8H2,1H3,(H,21,25)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.43E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393146
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Cn1cccc1CNC(=O)c1ccc(CNS(=O)(=O)c2ccc(F)c(Cl)c2)cn1
Show InChI InChI=1S/C19H18ClFN4O3S/c1-25-8-2-3-14(25)12-23-19(26)18-7-4-13(10-22-18)11-24-29(27,28)15-5-6-17(21)16(20)9-15/h2-10,24H,11-12H2,1H3,(H,23,26)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.55E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393175
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Cc1nnc(CNC(=O)c2ccc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)cn2)o1
Show InChI InChI=1S/C17H15ClFN5O4S/c1-10-23-24-16(28-10)9-21-17(25)15-5-2-11(7-20-15)8-22-29(26,27)12-3-4-14(19)13(18)6-12/h2-7,22H,8-9H2,1H3,(H,21,25)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.83E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393228
PNG
(5-(4- fluorobenzenesulfon- amidomethyl)-N-[(2- met...)
Show SMILES Cc1ncc(CNC(=O)c2ccc(CNS(=O)(=O)c3ccc(F)cc3)cn2)s1
Show InChI InChI=1S/C18H17FN4O3S2/c1-12-20-10-15(27-12)11-22-18(24)17-7-2-13(8-21-17)9-23-28(25,26)16-5-3-14(19)4-6-16/h2-8,10,23H,9,11H2,1H3,(H,22,24)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.84E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393142
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES COc1cc(CNC(=O)c2ccc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)cn2)ccn1
Show InChI InChI=1S/C20H18ClFN4O4S/c1-30-19-8-13(6-7-23-19)10-25-20(27)18-5-2-14(11-24-18)12-26-31(28,29)15-3-4-17(22)16(21)9-15/h2-9,11,26H,10,12H2,1H3,(H,25,27)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.02E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393105
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Cn1cccc1CNC(=O)c1cnc(CNS(=O)(=O)c2ccc(F)c(Cl)c2)cn1
Show InChI InChI=1S/C18H17ClFN5O3S/c1-25-6-2-3-13(25)10-23-18(26)17-11-21-12(8-22-17)9-24-29(27,28)14-4-5-16(20)15(19)7-14/h2-8,11,24H,9-10H2,1H3,(H,23,26)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.09E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393041
PNG
(5-(3-chloro-4- fluorobenzenesulfon- midomethyl)-N-...)
Show SMILES COc1cccc(CNC(=O)c2ccc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)cn2)c1
Show InChI InChI=1S/C21H19ClFN3O4S/c1-30-16-4-2-3-14(9-16)11-25-21(27)20-8-5-15(12-24-20)13-26-31(28,29)17-6-7-19(23)18(22)10-17/h2-10,12,26H,11,13H2,1H3,(H,25,27)
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PC cid
PC sid
UniChem
US Patent
n/an/a 3.37E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393259
PNG
(N-[(2-methyl-1,3- thiazol-5-yl)methyl]-5- (thiophe...)
Show SMILES Cc1ncc(CNC(=O)c2cnc(CNS(=O)(=O)c3cccs3)cn2)s1
Show InChI InChI=1S/C15H15N5O3S3/c1-10-16-7-12(25-10)8-19-15(21)13-9-17-11(5-18-13)6-20-26(22,23)14-3-2-4-24-14/h2-5,7,9,20H,6,8H2,1H3,(H,19,21)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.77E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393233
PNG
(N-[(2-methyl-1,3- thiazol-5-yl)methyl]-5- (thiophe...)
Show SMILES Cc1ncc(CNC(=O)c2ccc(CNS(=O)(=O)c3cccs3)cn2)s1
Show InChI InChI=1S/C16H16N4O3S3/c1-11-17-9-13(25-11)10-19-16(21)14-5-4-12(7-18-14)8-20-26(22,23)15-3-2-6-24-15/h2-7,9,20H,8,10H2,1H3,(H,19,21)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4.02E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393042
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Cn1cc(CNC(=O)c2ccc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)cn2)cn1
Show InChI InChI=1S/C18H17ClFN5O3S/c1-25-11-13(9-23-25)8-22-18(26)17-5-2-12(7-21-17)10-24-29(27,28)14-3-4-16(20)15(19)6-14/h2-7,9,11,24H,8,10H2,1H3,(H,22,26)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4.59E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393180
PNG
(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Show SMILES Fc1ccc(cc1Cl)S(=O)(=O)NCc1cnc(cn1)C(=O)NCc1cncnc1
Show InChI InChI=1S/C17H14ClFN6O3S/c18-14-3-13(1-2-15(14)19)29(27,28)25-8-12-7-23-16(9-22-12)17(26)24-6-11-4-20-10-21-5-11/h1-5,7,9-10,25H,6,8H2,(H,24,26)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4.84E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
NMDA receptor subtype 2A protein (NR2A)


(Homo sapiens (Human))
BDBM393241
PNG
(5-(4- fluorobenzenesulfon- midomethyl)-N-[(2- meth...)
Show SMILES Cc1ncc(CNC(=O)c2cnc(CNS(=O)(=O)c3ccc(F)cc3)cn2)s1
Show InChI InChI=1S/C17H16FN5O3S2/c1-11-19-8-14(27-11)9-22-17(24)16-10-20-13(6-21-16)7-23-28(25,26)15-4-2-12(18)3-5-15/h2-6,8,10,23H,7,9H2,1H3,(H,22,24)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.51E+3n/an/an/an/an/an/a



Luc Therapeutics, Inc.

US Patent


Assay Description
Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...


US Patent US9963434 (2018)

More data for this
Ligand-Target Pair
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* indicates data uncertainty>20%