BindingDB logo
myBDB logout

Patent code US9969723

Compile Data Set for Download or QSAR
Found 53 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393622
PNG
(US9969723, 4)
Show SMILES CC#CC(CC(O)=O)c1ccc(OCc2cccc(c2)C2=CCC(=O)CC2)cc1
Show InChI InChI=1S/C25H24O4/c1-2-4-21(16-25(27)28)20-9-13-24(14-10-20)29-17-18-5-3-6-22(15-18)19-7-11-23(26)12-8-19/h3,5-7,9-10,13-15,21H,8,11-12,16-17H2,1H3,(H,27,28)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393668
PNG
(US9969723, 50)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CCN3CCc4ccccc4C3)cc2)cc1
Show InChI InChI=1S/C30H31NO3/c1-2-5-27(20-30(32)33)26-12-14-29(15-13-26)34-22-24-10-8-23(9-11-24)16-18-31-19-17-25-6-3-4-7-28(25)21-31/h3-4,6-15,27H,16-22H2,1H3,(H,32,33)/t27-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393632
PNG
(US9969723, 14)
Show SMILES CC#CC(CC(O)=O)c1ccc(OCc2ccc(CN3CCC(=CC3)c3ccccc3)cc2)cc1
Show InChI InChI=1S/C31H31NO3/c1-2-6-29(21-31(33)34)27-13-15-30(16-14-27)35-23-25-11-9-24(10-12-25)22-32-19-17-28(18-20-32)26-7-4-3-5-8-26/h3-5,7-17,29H,18-23H2,1H3,(H,33,34)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<200n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393637
PNG
(US9969723, 19)
Show SMILES CC#CC(CC(O)=O)c1ccc(OCc2ccc(CN3CCN(CC3)c3ccc(cc3)C(F)(F)F)cc2)cc1
Show InChI InChI=1S/C31H31F3N2O3/c1-2-3-26(20-30(37)38)25-8-14-29(15-9-25)39-22-24-6-4-23(5-7-24)21-35-16-18-36(19-17-35)28-12-10-27(11-13-28)31(32,33)34/h4-15,26H,16-22H2,1H3,(H,37,38)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393640
PNG
(US9969723, 22)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCN(CC3)c3ccc(cc3)C(F)(F)F)cc2)cc1
Show InChI InChI=1S/C31H31F3N2O3/c1-2-3-26(20-30(37)38)25-8-14-29(15-9-25)39-22-24-6-4-23(5-7-24)21-35-16-18-36(19-17-35)28-12-10-27(11-13-28)31(32,33)34/h4-15,26H,16-22H2,1H3,(H,37,38)/t26-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393643
PNG
(US9969723, 25)
Show SMILES COc1ccc2CN(Cc3ccc(COc4ccc(cc4)[C@H](CC(O)=O)C#CC)cc3)CCc2c1
Show InChI InChI=1S/C30H31NO4/c1-3-4-25(18-30(32)33)24-9-12-28(13-10-24)35-21-23-7-5-22(6-8-23)19-31-16-15-26-17-29(34-2)14-11-27(26)20-31/h5-14,17,25H,15-16,18-21H2,1-2H3,(H,32,33)/t25-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393649
PNG
(US9969723, 31)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCN(CC3)c3noc(n3)C(C)C)cc2)cc1
Show InChI InChI=1S/C29H34N4O4/c1-4-5-25(18-27(34)35)24-10-12-26(13-11-24)36-20-23-8-6-22(7-9-23)19-32-14-16-33(17-15-32)29-30-28(21(2)3)37-31-29/h6-13,21,25H,14-20H2,1-3H3,(H,34,35)/t25-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393659
PNG
(US9969723, 41 | US9969723, 42)
Show SMILES CC#C[C@@H](CC([O-])=O)c1ccc(OCc2ccc(CN3CCCc4ccccc34)cc2)cc1
Show InChI InChI=1S/C29H29NO3/c1-2-6-26(19-29(31)32)24-14-16-27(17-15-24)33-21-23-12-10-22(11-13-23)20-30-18-5-8-25-7-3-4-9-28(25)30/h3-4,7,9-17,26H,5,8,18-21H2,1H3,(H,31,32)/p-1/t26-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393671
PNG
(US9969723, Comparative Example 2)
Show SMILES CC#C[C@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCC4(CCc5ccccc45)CC3)cc2)cc1
Show InChI InChI=1S/C33H35NO3/c1-2-5-29(22-32(35)36)27-12-14-30(15-13-27)37-24-26-10-8-25(9-11-26)23-34-20-18-33(19-21-34)17-16-28-6-3-4-7-31(28)33/h3-4,6-15,29H,16-24H2,1H3,(H,35,36)/t29-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393633
PNG
(US9969723, 15)
Show SMILES CC#CC(CC(O)=O)c1ccc(OCc2ccc(CN3CCN(CC3)c3ccccc3)cc2)cc1
Show InChI InChI=1S/C30H32N2O3/c1-2-6-27(21-30(33)34)26-13-15-29(16-14-26)35-23-25-11-9-24(10-12-25)22-31-17-19-32(20-18-31)28-7-4-3-5-8-28/h3-5,7-16,27H,17-23H2,1H3,(H,33,34)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393634
PNG
(US9969723, 16)
Show SMILES COc1ccc2CN(Cc3ccc(COc4ccc(cc4)C(CC(O)=O)C#CC)cc3)CCc2c1
Show InChI InChI=1S/C30H31NO4/c1-3-4-25(18-30(32)33)24-9-12-28(13-10-24)35-21-23-7-5-22(6-8-23)19-31-16-15-26-17-29(34-2)14-11-27(26)20-31/h5-14,17,25H,15-16,18-21H2,1-2H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393641
PNG
(US9969723, 23)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCN(CC3)c3ccc(F)cc3)cc2)cc1
Show InChI InChI=1S/C30H31FN2O3/c1-2-3-26(20-30(34)35)25-8-14-29(15-9-25)36-22-24-6-4-23(5-7-24)21-32-16-18-33(19-17-32)28-12-10-27(31)11-13-28/h4-15,26H,16-22H2,1H3,(H,34,35)/t26-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 250n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393651
PNG
(US9969723, 33)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCC(=CC3)c3ccc(OCCCS(C)(=O)=O)cc3)cc2)cc1
Show InChI InChI=1S/C35H39NO6S/c1-3-5-32(24-35(37)38)30-12-16-34(17-13-30)42-26-28-8-6-27(7-9-28)25-36-20-18-31(19-21-36)29-10-14-33(15-11-29)41-22-4-23-43(2,39)40/h6-18,32H,4,19-26H2,1-2H3,(H,37,38)/t32-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393665
PNG
(US9969723, 47)
Show SMILES COc1ccc(cc1)N1CCN(CC1)c1cccc(COc2ccc(cc2)[C@H](CC([O-])=O)C#CC)c1
Show InChI InChI=1S/C30H32N2O4/c1-3-5-25(21-30(33)34)24-8-12-29(13-9-24)36-22-23-6-4-7-27(20-23)32-18-16-31(17-19-32)26-10-14-28(35-2)15-11-26/h4,6-15,20,25H,16-19,21-22H2,1-2H3,(H,33,34)/p-1/t25-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 250n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393670
PNG
(US9969723, Comparative Example 1)
Show SMILES Cc1cccc(C)c1-c1ccc(OCCCS(C)(=O)=O)c(COc2ccc3[C@H](CC(O)=O)COc3c2)c1
Show InChI InChI=1S/C29H32O7S/c1-19-6-4-7-20(2)29(19)21-8-11-26(34-12-5-13-37(3,32)33)23(14-21)18-35-24-9-10-25-22(15-28(30)31)17-36-27(25)16-24/h4,6-11,14,16,22H,5,12-13,15,17-18H2,1-3H3,(H,30,31)/t22-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 250n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393626
PNG
(US9969723, 8)
Show SMILES CC#C[C@H](CC(O)=O)c1ccc(OCc2cccc(c2)C2=CCC3(CC2)OCCO3)cc1
Show InChI InChI=1S/C27H28O5/c1-2-4-23(18-26(28)29)21-7-9-25(10-8-21)30-19-20-5-3-6-24(17-20)22-11-13-27(14-12-22)31-15-16-32-27/h3,5-11,17,23H,12-16,18-19H2,1H3,(H,28,29)/t23-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393628
PNG
(US9969723, 10)
Show SMILES CC#C[C@H](CC([O-])=O)c1ccc(OCc2cccc(c2)C2=CCC3(CC2)OCCO3)cc1
Show InChI InChI=1S/C27H28O5/c1-2-4-23(18-26(28)29)21-7-9-25(10-8-21)30-19-20-5-3-6-24(17-20)22-11-13-27(14-12-22)31-15-16-32-27/h3,5-11,17,23H,12-16,18-19H2,1H3,(H,28,29)/p-1/t23-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393630
PNG
(US9969723, 12)
Show SMILES CC#CC(CC(O)=O)c1ccc(OCc2ccc(CN3CCc4ccccc4C3)cc2)cc1
Show InChI InChI=1S/C29H29NO3/c1-2-5-26(18-29(31)32)25-12-14-28(15-13-25)33-21-23-10-8-22(9-11-23)19-30-17-16-24-6-3-4-7-27(24)20-30/h3-4,6-15,26H,16-21H2,1H3,(H,31,32)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<200n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393636
PNG
(US9969723, 18)
Show SMILES CC#CC(CC(O)=O)c1ccc(OCc2ccc(CN3CCN(CC3)c3ccc(F)cc3)cc2)cc1
Show InChI InChI=1S/C30H31FN2O3/c1-2-3-26(20-30(34)35)25-8-14-29(15-9-25)36-22-24-6-4-23(5-7-24)21-32-16-18-33(19-17-32)28-12-10-27(31)11-13-28/h4-15,26H,16-22H2,1H3,(H,34,35)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393645
PNG
(US9969723, 27)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3Cc4ccccc4C3)cc2)cc1
Show InChI InChI=1S/C28H27NO3/c1-2-5-24(16-28(30)31)23-12-14-27(15-13-23)32-20-22-10-8-21(9-11-22)17-29-18-25-6-3-4-7-26(25)19-29/h3-4,6-15,24H,16-20H2,1H3,(H,30,31)/t24-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<200n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393646
PNG
(US9969723, 28)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCC(=CC3)c3ccccc3)cc2)cc1
Show InChI InChI=1S/C31H31NO3/c1-2-6-29(21-31(33)34)27-13-15-30(16-14-27)35-23-25-11-9-24(10-12-25)22-32-19-17-28(18-20-32)26-7-4-3-5-8-26/h3-5,7-17,29H,18-23H2,1H3,(H,33,34)/t29-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<200n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393658
PNG
(US9969723, 40)
Show SMILES COc1ccc(cc1)N1CCN(Cc2ccc(COc3ccc(cc3)[C@H](CC(O)=O)C#CC)cc2)CC1
Show InChI InChI=1S/C31H34N2O4/c1-3-4-27(21-31(34)35)26-9-13-30(14-10-26)37-23-25-7-5-24(6-8-25)22-32-17-19-33(20-18-32)28-11-15-29(36-2)16-12-28/h5-16,27H,17-23H2,1-2H3,(H,34,35)/t27-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 250n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393618
PNG
(US9969723, 1)
Show SMILES CC#CC(CC(O)=O)c1ccc(OCc2cccc(c2)C2=CCC3(CC2)OCCO3)cc1
Show InChI InChI=1S/C27H28O5/c1-2-4-23(18-26(28)29)21-7-9-25(10-8-21)30-19-20-5-3-6-24(17-20)22-11-13-27(14-12-22)31-15-16-32-27/h3,5-11,17,23H,12-16,18-19H2,1H3,(H,28,29)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393624
PNG
(US9969723, 6)
Show SMILES CC#CC(CC([O-])=O)c1ccc(OCc2cccc(c2)C2=CCC(O)CC2)cc1
Show InChI InChI=1S/C25H26O4/c1-2-4-21(16-25(27)28)20-9-13-24(14-10-20)29-17-18-5-3-6-22(15-18)19-7-11-23(26)12-8-19/h3,5-7,9-10,13-15,21,23,26H,8,11-12,16-17H2,1H3,(H,27,28)/p-1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 250n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393639
PNG
(US9969723, 21)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCc4ccccc4C3)cc2)cc1
Show InChI InChI=1S/C29H29NO3/c1-2-5-26(18-29(31)32)25-12-14-28(15-13-25)33-21-23-10-8-22(9-11-23)19-30-17-16-24-6-3-4-7-27(24)20-30/h3-4,6-15,26H,16-21H2,1H3,(H,31,32)/t26-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 250n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393653
PNG
(US9969723, 35)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCN(CC3)c3ccc(O)cc3)cc2)cc1
Show InChI InChI=1S/C30H32N2O4/c1-2-3-26(20-30(34)35)25-8-14-29(15-9-25)36-22-24-6-4-23(5-7-24)21-31-16-18-32(19-17-31)27-10-12-28(33)13-11-27/h4-15,26,33H,16-22H2,1H3,(H,34,35)/t26-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393655
PNG
(US9969723, 37 | US9969723, 38)
Show SMILES CC#C[C@@H](CC([O-])=O)c1ccc(OCc2ccc(CN3Cc4ccccc4C3)cc2)cc1
Show InChI InChI=1S/C28H27NO3/c1-2-5-24(16-28(30)31)23-12-14-27(15-13-23)32-20-22-10-8-21(9-11-22)17-29-18-25-6-3-4-7-26(25)19-29/h3-4,6-15,24H,16-20H2,1H3,(H,30,31)/p-1/t24-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<200n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393662
PNG
(US9969723, 44)
Show SMILES CCCc1cnc(nc1)N1CCN(Cc2ccc(COc3ccc(cc3)[C@H](CC(O)=O)C#CC)cc2)CC1
Show InChI InChI=1S/C31H36N4O3/c1-3-5-26-20-32-31(33-21-26)35-17-15-34(16-18-35)22-24-7-9-25(10-8-24)23-38-29-13-11-27(12-14-29)28(6-4-2)19-30(36)37/h7-14,20-21,28H,3,5,15-19,22-23H2,1-2H3,(H,36,37)/t28-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393667
PNG
(US9969723, 49)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CCN3Cc4ccccc4C3)cc2)cc1
Show InChI InChI=1S/C29H29NO3/c1-2-5-25(18-29(31)32)24-12-14-28(15-13-24)33-21-23-10-8-22(9-11-23)16-17-30-19-26-6-3-4-7-27(26)20-30/h3-4,6-15,25H,16-21H2,1H3,(H,31,32)/t25-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393669
PNG
(US9969723, 51)
Show SMILES COc1ccc2CN(Cc3ccc(COc4ccc(cc4)[C@H](CC([O-])=O)C#CC)cc3)CCc2c1
Show InChI InChI=1S/C30H31NO4/c1-3-4-25(18-30(32)33)24-9-12-28(13-10-24)35-21-23-7-5-22(6-8-23)19-31-16-15-26-17-29(34-2)14-11-27(26)20-31/h5-14,17,25H,15-16,18-21H2,1-2H3,(H,32,33)/p-1/t25-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393620
PNG
(US9969723, 2)
Show SMILES CC#CC(CC([O-])=O)c1ccc(OCc2cccc(c2)C2=CCC3(CC2)OCCO3)cc1
Show InChI InChI=1S/C27H28O5/c1-2-4-23(18-26(28)29)21-7-9-25(10-8-21)30-19-20-5-3-6-24(17-20)22-11-13-27(14-12-22)31-15-16-32-27/h3,5-11,17,23H,12-16,18-19H2,1H3,(H,28,29)/p-1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393659
PNG
(US9969723, 41 | US9969723, 42)
Show SMILES CC#C[C@@H](CC([O-])=O)c1ccc(OCc2ccc(CN3CCCc4ccccc34)cc2)cc1
Show InChI InChI=1S/C29H29NO3/c1-2-6-26(19-29(31)32)24-14-16-27(17-15-24)33-21-23-12-10-22(11-13-23)20-30-18-5-8-25-7-3-4-9-28(25)30/h3-4,7,9-17,26H,5,8,18-21H2,1H3,(H,31,32)/p-1/t26-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393627
PNG
(US9969723, 11 | US9969723, 9)
Show SMILES CC#C[C@@H](CC([O-])=O)c1ccc(OCc2cccc(c2)C2=CCC3(CC2)OCCO3)cc1
Show InChI InChI=1S/C27H28O5/c1-2-4-23(18-26(28)29)21-7-9-25(10-8-21)30-19-20-5-3-6-24(17-20)22-11-13-27(14-12-22)31-15-16-32-27/h3,5-11,17,23H,12-16,18-19H2,1H3,(H,28,29)/p-1/t23-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<200n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393635
PNG
(US9969723, 17)
Show SMILES CC#CC(CC(O)=O)c1ccc(OCc2ccc(CN3CCC(CC3)c3ccccc3)cc2)cc1
Show InChI InChI=1S/C31H33NO3/c1-2-6-29(21-31(33)34)27-13-15-30(16-14-27)35-23-25-11-9-24(10-12-25)22-32-19-17-28(18-20-32)26-7-4-3-5-8-26/h3-5,7-16,28-29H,17-23H2,1H3,(H,33,34)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393638
PNG
(US9969723, 20)
Show SMILES CC#CC(CC(O)=O)c1ccc(OCc2ccc(CN3CCN(CC3)c3ccc(OCCCS(C)(=O)=O)cc3)cc2)cc1
Show InChI InChI=1S/C34H40N2O6S/c1-3-5-30(24-34(37)38)29-10-14-33(15-11-29)42-26-28-8-6-27(7-9-28)25-35-18-20-36(21-19-35)31-12-16-32(17-13-31)41-22-4-23-43(2,39)40/h6-17,30H,4,18-26H2,1-2H3,(H,37,38)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393644
PNG
(US9969723, 26)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCC(CC3)c3ccccc3)cc2)cc1
Show InChI InChI=1S/C31H33NO3/c1-2-6-29(21-31(33)34)27-13-15-30(16-14-27)35-23-25-11-9-24(10-12-25)22-32-19-17-28(18-20-32)26-7-4-3-5-8-26/h3-5,7-16,28-29H,17-23H2,1H3,(H,33,34)/t29-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393650
PNG
(US9969723, 32)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCC(=CC3)c3ccc(cc3)S(C)(=O)=O)cc2)cc1
Show InChI InChI=1S/C32H33NO5S/c1-3-4-29(21-32(34)35)27-9-13-30(14-10-27)38-23-25-7-5-24(6-8-25)22-33-19-17-28(18-20-33)26-11-15-31(16-12-26)39(2,36)37/h5-17,29H,18-23H2,1-2H3,(H,34,35)/t29-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393664
PNG
(US9969723, 46)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCC(C3)c3ccccc3)cc2)cc1
Show InChI InChI=1S/C30H31NO3/c1-2-6-27(19-30(32)33)26-13-15-29(16-14-26)34-22-24-11-9-23(10-12-24)20-31-18-17-28(21-31)25-7-4-3-5-8-25/h3-5,7-16,27-28H,17-22H2,1H3,(H,32,33)/t27-,28?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393621
PNG
(US9969723, 3)
Show SMILES CC#CC(CC([O-])=O)c1ccc(Oc2ccc(cc2)C2=CCC3(CC2)OCCO3)cc1
Show InChI InChI=1S/C26H26O5/c1-2-3-22(18-25(27)28)20-6-10-24(11-7-20)31-23-8-4-19(5-9-23)21-12-14-26(15-13-21)29-16-17-30-26/h4-12,22H,13-18H2,1H3,(H,27,28)/p-1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393625
PNG
(US9969723, 7)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2cccc(c2)C2=CCC3(CC2)OCCO3)cc1
Show InChI InChI=1S/C27H28O5/c1-2-4-23(18-26(28)29)21-7-9-25(10-8-21)30-19-20-5-3-6-24(17-20)22-11-13-27(14-12-22)31-15-16-32-27/h3,5-11,17,23H,12-16,18-19H2,1H3,(H,28,29)/t23-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<200n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393631
PNG
(US9969723, 13)
Show SMILES CC#CC(CC(O)=O)c1ccc(OCc2ccc(CN3CCc4ccccc4C3)c(c2)C2=CCCCC2)cc1
Show InChI InChI=1S/C35H37NO3/c1-2-8-30(22-35(37)38)28-15-17-33(18-16-28)39-25-26-13-14-32(34(21-26)29-10-4-3-5-11-29)24-36-20-19-27-9-6-7-12-31(27)23-36/h6-7,9-10,12-18,21,30H,3-5,11,19-20,22-25H2,1H3,(H,37,38)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393642
PNG
(US9969723, 24)
Show SMILES CC#C[C@@H](CC([O-])=O)c1ccc(OCc2ccc(CN3CCN(CC3)c3ccc(cc3)C(F)(F)F)cc2)cc1
Show InChI InChI=1S/C31H31F3N2O3/c1-2-3-26(20-30(37)38)25-8-14-29(15-9-25)39-22-24-6-4-23(5-7-24)21-35-16-18-36(19-17-35)28-12-10-27(11-13-28)31(32,33)34/h4-15,26H,16-22H2,1H3,(H,37,38)/p-1/t26-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 250n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393647
PNG
(US9969723, 29)
Show SMILES COCOc1ccc(cc1)N1CCN(Cc2ccc(COc3ccc(cc3)[C@H](CC(O)=O)C#CC)cc2)CC1
Show InChI InChI=1S/C32H36N2O5/c1-3-4-28(21-32(35)36)27-9-13-30(14-10-27)38-23-26-7-5-25(6-8-26)22-33-17-19-34(20-18-33)29-11-15-31(16-12-29)39-24-37-2/h5-16,28H,17-24H2,1-2H3,(H,35,36)/t28-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 250n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393654
PNG
(US9969723, 36)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCN(CC3)c3ccc(OCCCS(C)(=O)=O)cc3)cc2)cc1
Show InChI InChI=1S/C34H40N2O6S/c1-3-5-30(24-34(37)38)29-10-14-33(15-11-29)42-26-28-8-6-27(7-9-28)25-35-18-20-36(21-19-35)31-12-16-32(17-13-31)41-22-4-23-43(2,39)40/h6-17,30H,4,18-26H2,1-2H3,(H,37,38)/t30-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393657
PNG
(US9969723, 39)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCC(=CC3)c3ccc(F)cc3)cc2)cc1
Show InChI InChI=1S/C31H30FNO3/c1-2-3-28(20-31(34)35)26-10-14-30(15-11-26)36-22-24-6-4-23(5-7-24)21-33-18-16-27(17-19-33)25-8-12-29(32)13-9-25/h4-16,28H,17-22H2,1H3,(H,34,35)/t28-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 250n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393661
PNG
(US9969723, 43)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCN(CC3)c3nc4ccccc4s3)cc2)cc1
Show InChI InChI=1S/C31H31N3O3S/c1-2-5-26(20-30(35)36)25-12-14-27(15-13-25)37-22-24-10-8-23(9-11-24)21-33-16-18-34(19-17-33)31-32-28-6-3-4-7-29(28)38-31/h3-4,6-15,26H,16-22H2,1H3,(H,35,36)/t26-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393666
PNG
(US9969723, 48)
Show SMILES COc1ccc2CN(CCc3ccc(COc4ccc(cc4)[C@H](CC(O)=O)C#CC)cc3)CCc2c1
Show InChI InChI=1S/C31H33NO4/c1-3-4-26(20-31(33)34)25-9-12-29(13-10-25)36-22-24-7-5-23(6-8-24)15-17-32-18-16-27-19-30(35-2)14-11-28(27)21-32/h5-14,19,26H,15-18,20-22H2,1-2H3,(H,33,34)/t26-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393627
PNG
(US9969723, 11 | US9969723, 9)
Show SMILES CC#C[C@@H](CC([O-])=O)c1ccc(OCc2cccc(c2)C2=CCC3(CC2)OCCO3)cc1
Show InChI InChI=1S/C27H28O5/c1-2-4-23(18-26(28)29)21-7-9-25(10-8-21)30-19-20-5-3-6-24(17-20)22-11-13-27(14-12-22)31-15-16-32-27/h3,5-11,17,23H,12-16,18-19H2,1H3,(H,28,29)/p-1/t23-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<200n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393648
PNG
(US9969723, 30)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCC(CC3)c3noc(n3)C(C)C)cc2)cc1
Show InChI InChI=1S/C30H35N3O4/c1-4-5-26(18-28(34)35)24-10-12-27(13-11-24)36-20-23-8-6-22(7-9-23)19-33-16-14-25(15-17-33)29-31-30(21(2)3)37-32-29/h6-13,21,25-26H,14-20H2,1-3H3,(H,34,35)/t26-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393652
PNG
(US9969723, 34)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(cc2)C(C)N2CCc3ccccc3C2)cc1
Show InChI InChI=1S/C30H31NO3/c1-3-6-27(19-30(32)33)26-13-15-29(16-14-26)34-21-23-9-11-24(12-10-23)22(2)31-18-17-25-7-4-5-8-28(25)20-31/h4-5,7-16,22,27H,17-21H2,1-2H3,(H,32,33)/t22?,27-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393655
PNG
(US9969723, 37 | US9969723, 38)
Show SMILES CC#C[C@@H](CC([O-])=O)c1ccc(OCc2ccc(CN3Cc4ccccc4C3)cc2)cc1
Show InChI InChI=1S/C28H27NO3/c1-2-5-24(16-28(30)31)23-12-14-27(15-13-23)32-20-22-10-8-21(9-11-22)17-29-18-25-6-3-4-7-26(25)19-29/h3-4,6-15,24H,16-20H2,1H3,(H,30,31)/p-1/t24-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<200n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393663
PNG
(US9969723, 45)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCN(CC3)c3ccc(cn3)C#N)cc2)cc1
Show InChI InChI=1S/C30H30N4O3/c1-2-3-27(18-30(35)36)26-9-11-28(12-10-26)37-22-24-6-4-23(5-7-24)21-33-14-16-34(17-15-33)29-13-8-25(19-31)20-32-29/h4-13,20,27H,14-18,21-22H2,1H3,(H,35,36)/t27-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>300n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM393623
PNG
(US9969723, 5)
Show SMILES CC#CC(CC(O)=O)c1ccc(OCc2cccc(c2)C2=CCC(O)CC2)cc1
Show InChI InChI=1S/C25H26O4/c1-2-4-21(16-25(27)28)20-9-13-24(14-10-20)29-17-18-5-3-6-22(15-18)19-7-11-23(26)12-8-19/h3,5-7,9-10,13-15,21,23,26H,8,11-12,16-17H2,1H3,(H,27,28)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 250n/an/an/an/a



HYUNDAI PHARM CO., LTD

US Patent


Assay Description
The GPR40 protein activity according to the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative of the present invention was measured by investi...


US Patent US9969723 (2018)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%