BindingDB logo
myBDB logout

Patent code USRE47141

Compile Data Set for Download or QSAR
Found 78 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
TGF-beta receptor type I


(Homo sapiens)
BDBM50015670
PNG
(CHEMBL3260583 | USRE47141, Example 20)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2cccc(Br)c2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H18BrN7/c1-14-4-2-7-18(27-14)22-21(15-8-9-20-25-13-26-30(20)12-15)28-19(29-22)11-24-17-6-3-5-16(23)10-17/h2-10,12-13,24H,11H2,1H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 4.53n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015679
PNG
(CHEMBL3260591 | USRE47141, Example 60)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2cccc(c2)C#N)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H18N8/c1-15-4-2-7-19(28-15)23-22(17-8-9-21-26-14-27-31(21)13-17)29-20(30-23)12-25-18-6-3-5-16(10-18)11-24/h2-10,13-14,25H,12H2,1H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 4.83n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015669
PNG
(CHEMBL3260582 | USRE47141, Example 12)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2cccc(Cl)c2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H18ClN7/c1-14-4-2-7-18(27-14)22-21(15-8-9-20-25-13-26-30(20)12-15)28-19(29-22)11-24-17-6-3-5-16(23)10-17/h2-10,12-13,24H,11H2,1H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 6.16n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015942
PNG
(CHEMBL3260623 | USRE47141, Example 9)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2cc(F)cc(F)c2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H17F2N7/c1-13-3-2-4-18(28-13)22-21(14-5-6-20-26-12-27-31(20)11-14)29-19(30-22)10-25-17-8-15(23)7-16(24)9-17/h2-9,11-12,25H,10H2,1H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 6.39n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015645
PNG
(CHEMBL3260569 | USRE47141, Example 18)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccccc2Br)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H18BrN7/c1-14-5-4-8-18(27-14)22-21(15-9-10-20-25-13-26-30(20)12-15)28-19(29-22)11-24-17-7-3-2-6-16(17)23/h2-10,12-13,24H,11H2,1H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 6.54n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015639
PNG
(CHEMBL3260567 | USRE47141, Example 2)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccccc2F)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H18FN7/c1-14-5-4-8-18(27-14)22-21(15-9-10-20-25-13-26-30(20)12-15)28-19(29-22)11-24-17-7-3-2-6-16(17)23/h2-10,12-13,24H,11H2,1H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 6.68n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015676
PNG
(CHEMBL3260589 | USRE47141, Example 55)
Show SMILES CSc1cccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)c1
Show InChI InChI=1S/C23H21N7S/c1-15-5-3-8-19(27-15)23-22(16-9-10-21-25-14-26-30(21)13-16)28-20(29-23)12-24-17-6-4-7-18(11-17)31-2/h3-11,13-14,24H,12H2,1-2H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 6.70n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015878
PNG
(CHEMBL3260620 | USRE47141, Example 16)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccc(Cl)c(Cl)c2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H17Cl2N7/c1-13-3-2-4-18(28-13)22-21(14-5-8-20-26-12-27-31(20)11-14)29-19(30-22)10-25-15-6-7-16(23)17(24)9-15/h2-9,11-12,25H,10H2,1H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 7.54n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015672
PNG
(CHEMBL3260585 | USRE47141, Example 31)
Show SMILES CCc1cccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)c1
Show InChI InChI=1S/C24H23N7/c1-3-17-7-5-8-19(12-17)25-13-21-29-23(18-10-11-22-26-15-27-31(22)14-18)24(30-21)20-9-4-6-16(2)28-20/h4-12,14-15,25H,3,13H2,1-2H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 8.01n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015838
PNG
(CHEMBL3260614 | USRE47141, Example 7)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2cccc(F)c2F)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H17F2N7/c1-13-4-2-7-17(28-13)22-21(14-8-9-19-26-12-27-31(19)11-14)29-18(30-22)10-25-16-6-3-5-15(23)20(16)24/h2-9,11-12,25H,10H2,1H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 8.96n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015671
PNG
(CHEMBL3260584 | USRE47141, Example 24)
Show SMILES Cc1cccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)c1
Show InChI InChI=1S/C23H21N7/c1-15-5-3-7-18(11-15)24-12-20-28-22(17-9-10-21-25-14-26-30(21)13-17)23(29-20)19-8-4-6-16(2)27-19/h3-11,13-14,24H,12H2,1-2H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 9.07n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015680
PNG
(CHEMBL3260592 | USRE47141, Example 66)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2cccc(c2)C(N)=O)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H20N8O/c1-14-4-2-7-18(28-14)22-21(16-8-9-20-26-13-27-31(20)12-16)29-19(30-22)11-25-17-6-3-5-15(10-17)23(24)32/h2-10,12-13,25H,11H2,1H3,(H2,24,32)(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 9.14n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM304156
PNG
(USRE47141, Example 138)
Show SMILES CCc1cccc(n1)-c1[nH]c(CNc2cccc(c2)C#N)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C24H20N8/c1-2-18-6-4-8-20(29-18)24-23(17-9-10-22-27-15-28-32(22)14-17)30-21(31-24)13-26-19-7-3-5-16(11-19)12-25/h3-11,14-15,26H,2,13H2,1H3,(H,30,31)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 9.40n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015668
PNG
(CHEMBL3260581 | USRE47141, Example 5)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2cccc(F)c2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H18FN7/c1-14-4-2-7-18(27-14)22-21(15-8-9-20-25-13-26-30(20)12-15)28-19(29-22)11-24-17-6-3-5-16(23)10-17/h2-10,12-13,24H,11H2,1H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 9.41n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015644
PNG
(CHEMBL3260568 | USRE47141, Example 10)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccccc2Cl)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H18ClN7/c1-14-5-4-8-18(27-14)22-21(15-9-10-20-25-13-26-30(20)12-15)28-19(29-22)11-24-17-7-3-2-6-16(17)23/h2-10,12-13,24H,11H2,1H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 9.41n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015845
PNG
(CHEMBL3260619 | USRE47141, Example 8)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccc(F)c(F)c2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H17F2N7/c1-13-3-2-4-18(28-13)22-21(14-5-8-20-26-12-27-31(20)11-14)29-19(30-22)10-25-15-6-7-16(23)17(24)9-15/h2-9,11-12,25H,10H2,1H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 9.84n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015661
PNG
(CHEMBL3260575 | USRE47141, Example 54)
Show SMILES CSc1ccccc1NCc1nc(c([nH]1)-c1cccc(C)n1)-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H21N7S/c1-15-6-5-8-18(27-15)23-22(16-10-11-21-25-14-26-30(21)13-16)28-20(29-23)12-24-17-7-3-4-9-19(17)31-2/h3-11,13-14,24H,12H2,1-2H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 9.93n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015647
PNG
(CHEMBL3260571 | USRE47141, Example 30)
Show SMILES CCc1ccccc1NCc1nc(c([nH]1)-c1cccc(C)n1)-c1ccc2ncnn2c1
Show InChI InChI=1S/C24H23N7/c1-3-17-8-4-5-9-19(17)25-13-21-29-23(18-11-12-22-26-15-27-31(22)14-18)24(30-21)20-10-6-7-16(2)28-20/h4-12,14-15,25H,3,13H2,1-2H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 10.6n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015690
PNG
(CHEMBL3260599 | USRE47141, Example 14)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccc(Cl)cc2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H18ClN7/c1-14-3-2-4-18(27-14)22-21(15-5-10-20-25-13-26-30(20)12-15)28-19(29-22)11-24-17-8-6-16(23)7-9-17/h2-10,12-13,24H,11H2,1H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 10.7n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM304144
PNG
(USRE47141, Example 68)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2cccc(C[N+]#[C-])c2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C24H20N8/c1-16-5-3-8-20(29-16)24-23(18-9-10-22-27-15-28-32(22)14-18)30-21(31-24)13-26-19-7-4-6-17(11-19)12-25-2/h3-11,14-15,26H,12-13H2,1H3,(H,30,31)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 11n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015678
PNG
(CHEMBL3260590 | USRE47141, Example 37)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2cccc(C=C)c2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C24H21N7/c1-3-17-7-5-8-19(12-17)25-13-21-29-23(18-10-11-22-26-15-27-31(22)14-18)24(30-21)20-9-4-6-16(2)28-20/h3-12,14-15,25H,1,13H2,2H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 11.9n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015839
PNG
(CHEMBL3260615 | USRE47141, Example 15)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2cccc(Cl)c2Cl)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H17Cl2N7/c1-13-4-2-7-17(28-13)22-21(14-8-9-19-26-12-27-31(19)11-14)29-18(30-22)10-25-16-6-3-5-15(23)20(16)24/h2-9,11-12,25H,10H2,1H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 12.3n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015660
PNG
(CHEMBL3260574 | USRE47141, Example 51)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccccc2OC(F)(F)F)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H18F3N7O/c1-14-5-4-7-17(30-14)22-21(15-9-10-20-28-13-29-33(20)12-15)31-19(32-22)11-27-16-6-2-3-8-18(16)34-23(24,25)26/h2-10,12-13,27H,11H2,1H3,(H,31,32)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 12.3n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM304163
PNG
(USRE47141, Example 145)
Show SMILES Cc1cccc(n1)-c1[nH]c(Cc2cccc(c2)C#N)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H17N7/c1-15-4-2-7-19(27-15)23-22(18-8-9-21-25-14-26-30(21)13-18)28-20(29-23)11-16-5-3-6-17(10-16)12-24/h2-10,13-14H,11H2,1H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 12.4n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015682
PNG
(CHEMBL3260594 | USRE47141, Example 70)
Show SMILES CC(=O)c1cccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)c1
Show InChI InChI=1S/C24H21N7O/c1-15-5-3-8-20(28-15)24-23(18-9-10-22-26-14-27-31(22)13-18)29-21(30-24)12-25-19-7-4-6-17(11-19)16(2)32/h3-11,13-14,25H,12H2,1-2H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 12.8n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015643
PNG
(CHEMBL3260566 | USRE47141, Example 1)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccccc2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H19N7/c1-15-6-5-9-18(26-15)22-21(16-10-11-20-24-14-25-29(20)13-16)27-19(28-22)12-23-17-7-3-2-4-8-17/h2-11,13-14,23H,12H2,1H3,(H,27,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 13.1n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015641
PNG
(CHEMBL3260564 | USRE47141, Example 148)
Show SMILES Cc1cccc(n1)-c1[nH]c(COc2ccccc2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H18N6O/c1-15-6-5-9-18(25-15)22-21(16-10-11-20-23-14-24-28(20)12-16)26-19(27-22)13-29-17-7-3-2-4-8-17/h2-12,14H,13H2,1H3,(H,26,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
US Patent
n/an/a 13.1n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015646
PNG
(CHEMBL3260570 | USRE47141, Example 23)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccccc2C)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H21N7/c1-15-6-3-4-8-18(15)24-12-20-28-22(17-10-11-21-25-14-26-30(21)13-17)23(29-20)19-9-5-7-16(2)27-19/h3-11,13-14,24H,12H2,1-2H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 13.9n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015656
PNG
(CHEMBL3260572 | USRE47141, Example 33)
Show SMILES CC(C)c1ccccc1NCc1nc(c([nH]1)-c1cccc(C)n1)-c1ccc2ncnn2c1
Show InChI InChI=1S/C25H25N7/c1-16(2)19-8-4-5-9-20(19)26-13-22-30-24(18-11-12-23-27-15-28-32(23)14-18)25(31-22)21-10-6-7-17(3)29-21/h4-12,14-16,26H,13H2,1-3H3,(H,30,31)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 14.2n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015663
PNG
(CHEMBL3260576 | USRE47141, Example 36)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccccc2C=C)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C24H21N7/c1-3-17-8-4-5-9-19(17)25-13-21-29-23(18-11-12-22-26-15-27-31(22)14-18)24(30-21)20-10-6-7-16(2)28-20/h3-12,14-15,25H,1,13H2,2H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 14.2n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015674
PNG
(CHEMBL3260587 | USRE47141, Example 43)
Show SMILES COc1cccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)c1
Show InChI InChI=1S/C23H21N7O/c1-15-5-3-8-19(27-15)23-22(16-9-10-21-25-14-26-30(21)13-16)28-20(29-23)12-24-17-6-4-7-18(11-17)31-2/h3-11,13-14,24H,12H2,1-2H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 14.3n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015944
PNG
(CHEMBL3260625 | USRE47141, Example 29)
Show SMILES Cc1cc(C)cc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)c1
Show InChI InChI=1S/C24H23N7/c1-15-9-16(2)11-19(10-15)25-12-21-29-23(18-7-8-22-26-14-27-31(22)13-18)24(30-21)20-6-4-5-17(3)28-20/h4-11,13-14,25H,12H2,1-3H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 14.3n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015659
PNG
(CHEMBL3260573 | USRE47141, Example 42)
Show SMILES COc1ccccc1NCc1nc(c([nH]1)-c1cccc(C)n1)-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H21N7O/c1-15-6-5-8-18(27-15)23-22(16-10-11-21-25-14-26-30(21)13-16)28-20(29-23)12-24-17-7-3-4-9-19(17)31-2/h3-11,13-14,24H,12H2,1-2H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 14.4n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015945
PNG
(CHEMBL3260626 | USRE47141, Example 47)
Show SMILES COc1cc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)cc(OC)c1
Show InChI InChI=1S/C24H23N7O2/c1-15-5-4-6-20(28-15)24-23(16-7-8-22-26-14-27-31(22)13-16)29-21(30-24)12-25-17-9-18(32-2)11-19(10-17)33-3/h4-11,13-14,25H,12H2,1-3H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 14.4n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015943
PNG
(CHEMBL3260624 | USRE47141, Example 17)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2cc(Cl)cc(Cl)c2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H17Cl2N7/c1-13-3-2-4-18(28-13)22-21(14-5-6-20-26-12-27-31(20)11-14)29-19(30-22)10-25-17-8-15(23)7-16(24)9-17/h2-9,11-12,25H,10H2,1H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 14.6n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015687
PNG
(CHEMBL3260596 | USRE47141, Example 78)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2cccc(NS(C)(=O)=O)c2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H22N8O2S/c1-15-5-3-8-19(27-15)23-22(16-9-10-21-25-14-26-31(21)13-16)28-20(29-23)12-24-17-6-4-7-18(11-17)30-34(2,32)33/h3-11,13-14,24,30H,12H2,1-2H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 15.1n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015666
PNG
(CHEMBL3260579 | USRE47141, Example 77)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccccc2NS(C)(=O)=O)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H22N8O2S/c1-15-6-5-9-19(27-15)23-22(16-10-11-21-25-14-26-31(21)13-16)28-20(29-23)12-24-17-7-3-4-8-18(17)30-34(2,32)33/h3-11,13-14,24,30H,12H2,1-2H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 15.3n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM304129
PNG
(USRE47141, Example 49)
Show SMILES COCc1cccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)c1
Show InChI InChI=1S/C24H23N7O/c1-16-5-3-8-20(28-16)24-23(18-9-10-22-26-15-27-31(22)13-18)29-21(30-24)12-25-19-7-4-6-17(11-19)14-32-2/h3-11,13,15,25H,12,14H2,1-2H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 15.3n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015688
PNG
(CHEMBL3260597 | USRE47141, Example 75)
Show SMILES CC(=O)Nc1cccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)c1
Show InChI InChI=1S/C24H22N8O/c1-15-5-3-8-20(28-15)24-23(17-9-10-22-26-14-27-32(22)13-17)30-21(31-24)12-25-18-6-4-7-19(11-18)29-16(2)33/h3-11,13-14,25H,12H2,1-2H3,(H,29,33)(H,30,31)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 15.4n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015693
PNG
(CHEMBL3260601 | USRE47141, Example 26)
Show SMILES Cc1ccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)cc1
Show InChI InChI=1S/C23H21N7/c1-15-6-9-18(10-7-15)24-12-20-28-22(17-8-11-21-25-14-26-30(21)13-17)23(29-20)19-5-3-4-16(2)27-19/h3-11,13-14,24H,12H2,1-2H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 15.6n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015673
PNG
(CHEMBL3260586 | USRE47141, Example 34)
Show SMILES CC(C)c1cccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)c1
Show InChI InChI=1S/C25H25N7/c1-16(2)18-7-5-8-20(12-18)26-13-22-30-24(19-10-11-23-27-15-28-32(23)14-19)25(31-22)21-9-4-6-17(3)29-21/h4-12,14-16,26H,13H2,1-3H3,(H,30,31)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 16.2n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015685
PNG
(CHEMBL3260595 | USRE47141, Example 72)
Show SMILES COC(=O)c1cccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)c1
Show InChI InChI=1S/C24H21N7O2/c1-15-5-3-8-19(28-15)23-22(17-9-10-21-26-14-27-31(21)13-17)29-20(30-23)12-25-18-7-4-6-16(11-18)24(32)33-2/h3-11,13-14,25H,12H2,1-2H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 16.6n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015691
PNG
(CHEMBL3260600 | USRE47141, Example 22)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccc(Br)cc2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H18BrN7/c1-14-3-2-4-18(27-14)22-21(15-5-10-20-25-13-26-30(20)12-15)28-19(29-22)11-24-17-8-6-16(23)7-9-17/h2-10,12-13,24H,11H2,1H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 17.1n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015689
PNG
(CHEMBL3260598 | USRE47141, Example 6)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccc(F)cc2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H18FN7/c1-14-3-2-4-18(27-14)22-21(15-5-10-20-25-13-26-30(20)12-15)28-19(29-22)11-24-17-8-6-16(23)7-9-17/h2-10,12-13,24H,11H2,1H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 17.4n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015940
PNG
(CHEMBL3260621 | USRE47141, Example 28)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccc(C)c(C)c2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C24H23N7/c1-15-7-9-19(11-16(15)2)25-12-21-29-23(18-8-10-22-26-14-27-31(22)13-18)24(30-21)20-6-4-5-17(3)28-20/h4-11,13-14,25H,12H2,1-3H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 17.4n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015840
PNG
(CHEMBL3260616 | USRE47141, Example 27)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2cccc(C)c2C)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C24H23N7/c1-15-6-4-8-19(17(15)3)25-12-21-29-23(18-10-11-22-26-14-27-31(22)13-18)24(30-21)20-9-5-7-16(2)28-20/h4-11,13-14,25H,12H2,1-3H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 18n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM304137
PNG
(USRE47141, Example 59)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccccc2[N+]#[C-])nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H18N8/c1-15-6-5-9-19(28-15)23-22(16-10-11-21-26-14-27-31(21)13-16)29-20(30-23)12-25-18-8-4-3-7-17(18)24-2/h3-11,13-14,25H,12H2,1H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 19.5n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM304161
PNG
(USRE47141, Example 143)
Show SMILES Cc1cccc(n1)-c1[nH]c(Cc2ccccc2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H18N6/c1-15-6-5-9-18(25-15)22-21(17-10-11-20-23-14-24-28(20)13-17)26-19(27-22)12-16-7-3-2-4-8-16/h2-11,13-14H,12H2,1H3,(H,26,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 19.8n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM304140
PNG
(USRE47141, Example 64)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2cccc(C#N)c2[N+]#[C-])nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C24H17N9/c1-15-5-3-8-19(30-15)24-23(17-9-10-21-28-14-29-33(21)13-17)31-20(32-24)12-27-18-7-4-6-16(11-25)22(18)26-2/h3-10,13-14,27H,12H2,1H3,(H,31,32)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 20.6n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015642
PNG
(CHEMBL3260565 | USRE47141, Example 152)
Show SMILES Cc1cccc(n1)-c1[nH]c(CSc2ccccc2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H18N6S/c1-15-6-5-9-18(25-15)22-21(16-10-11-20-23-14-24-28(20)12-16)26-19(27-22)13-29-17-7-3-2-4-8-17/h2-12,14H,13H2,1H3,(H,26,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

US Patent
n/an/a 20.7n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM304168
PNG
(USRE47141, Example 151)
Show SMILES Cc1cccc(n1)-c1[nH]c(COc2cccc(c2)C(N)=O)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H19N7O2/c1-14-4-2-7-18(27-14)22-21(16-8-9-20-25-13-26-30(20)11-16)28-19(29-22)12-32-17-6-3-5-15(10-17)23(24)31/h2-11,13H,12H2,1H3,(H2,24,31)(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 22.5n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM304157
PNG
(USRE47141, Example 139)
Show SMILES CCc1cccc(n1)-c1[nH]c(CNc2ccccc2F)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H20FN7/c1-2-16-6-5-9-19(28-16)23-22(15-10-11-21-26-14-27-31(21)13-15)29-20(30-23)12-25-18-8-4-3-7-17(18)24/h3-11,13-14,25H,2,12H2,1H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 23.2n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015675
PNG
(CHEMBL3260588 | USRE47141, Example 52)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2cccc(OC(F)(F)F)c2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H18F3N7O/c1-14-4-2-7-18(30-14)22-21(15-8-9-20-28-13-29-33(20)12-15)31-19(32-22)11-27-16-5-3-6-17(10-16)34-23(24,25)26/h2-10,12-13,27H,11H2,1H3,(H,31,32)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 23.4n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM304167
PNG
(USRE47141, Example 150)
Show SMILES Cc1cccc(n1)-c1[nH]c(COc2cccc(c2)C#N)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H17N7O/c1-15-4-2-7-19(27-15)23-22(17-8-9-21-25-14-26-30(21)12-17)28-20(29-23)13-31-18-6-3-5-16(10-18)11-24/h2-10,12,14H,13H2,1H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 23.9n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM304128
PNG
(USRE47141, Example 48)
Show SMILES COCc1ccccc1NCc1nc(c([nH]1)-c1cccc(C)n1)-c1ccc2ncnn2c1
Show InChI InChI=1S/C24H23N7O/c1-16-6-5-9-20(28-16)24-23(17-10-11-22-26-15-27-31(22)13-17)29-21(30-24)12-25-19-8-4-3-7-18(19)14-32-2/h3-11,13,15,25H,12,14H2,1-2H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 24.1n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015762
PNG
(CHEMBL3260609 | USRE47141, Example 69)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccc(CC#N)cc2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C24H20N8/c1-16-3-2-4-20(29-16)24-23(18-7-10-22-27-15-28-32(22)14-18)30-21(31-24)13-26-19-8-5-17(6-9-19)11-12-25/h2-10,14-15,26H,11,13H2,1H3,(H,30,31)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 24.5n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM304162
PNG
(USRE47141, Example 144)
Show SMILES Cc1cccc(n1)-c1[nH]c(Cc2ccccc2F)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H17FN6/c1-14-5-4-8-18(26-14)22-21(16-9-10-20-24-13-25-29(20)12-16)27-19(28-22)11-15-6-2-3-7-17(15)23/h2-10,12-13H,11H2,1H3,(H,27,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 25.1n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM304166
PNG
(USRE47141, Example 149)
Show SMILES Cc1cccc(n1)-c1[nH]c(COc2ccccc2F)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C22H17FN6O/c1-14-5-4-7-17(26-14)22-21(15-9-10-20-24-13-25-29(20)11-15)27-19(28-22)12-30-18-8-3-2-6-16(18)23/h2-11,13H,12H2,1H3,(H,27,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 25.4n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015706
PNG
(CHEMBL3260606 | USRE47141, Example 40)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccc(C=C)cc2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C24H21N7/c1-3-17-7-10-19(11-8-17)25-13-21-29-23(18-9-12-22-26-15-27-31(22)14-18)24(30-21)20-6-4-5-16(2)28-20/h3-12,14-15,25H,1,13H2,2H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 29.6n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015665
PNG
(CHEMBL3260578 | USRE47141, Example 65)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccccc2C(N)=O)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H20N8O/c1-14-5-4-8-18(28-14)22-21(15-9-10-20-26-13-27-31(20)12-15)29-19(30-22)11-25-17-7-3-2-6-16(17)23(24)32/h2-10,12-13,25H,11H2,1H3,(H2,24,32)(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 29.7n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015729
PNG
(CHEMBL3260607 | USRE47141, Example 63)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccc(cc2)C#N)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H18N8/c1-15-3-2-4-19(28-15)23-22(17-7-10-21-26-14-27-31(21)13-17)29-20(30-23)12-25-18-8-5-16(11-24)6-9-18/h2-10,13-14,25H,12H2,1H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 32.1n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015837
PNG
(CHEMBL3260613 | USRE47141, Example 76)
Show SMILES CC(=O)Nc1ccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)cc1
Show InChI InChI=1S/C24H22N8O/c1-15-4-3-5-20(28-15)24-23(17-6-11-22-26-14-27-32(22)13-17)30-21(31-24)12-25-18-7-9-19(10-8-18)29-16(2)33/h3-11,13-14,25H,12H2,1-2H3,(H,29,33)(H,30,31)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 39n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015667
PNG
(CHEMBL3260580 | USRE47141, Example 74)
Show SMILES CC(=O)Nc1ccccc1NCc1nc(c([nH]1)-c1cccc(C)n1)-c1ccc2ncnn2c1
Show InChI InChI=1S/C24H22N8O/c1-15-6-5-9-20(28-15)24-23(17-10-11-22-26-14-27-32(22)13-17)30-21(31-24)12-25-18-7-3-4-8-19(18)29-16(2)33/h3-11,13-14,25H,12H2,1-2H3,(H,29,33)(H,30,31)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 39.5n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015705
PNG
(CHEMBL3260605 | USRE47141, Example 58)
Show SMILES CSc1ccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)cc1
Show InChI InChI=1S/C23H21N7S/c1-15-4-3-5-19(27-15)23-22(16-6-11-21-25-14-26-30(21)13-16)28-20(29-23)12-24-17-7-9-18(31-2)10-8-17/h3-11,13-14,24H,12H2,1-2H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 39.6n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM304164
PNG
(USRE47141, Example 147)
Show SMILES Cc1cccc(n1)-c1[nH]c(Cc2cccc(c2)C(N)=O)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H19N7O/c1-14-4-2-7-18(27-14)22-21(17-8-9-20-25-13-26-30(20)12-17)28-19(29-22)11-15-5-3-6-16(10-15)23(24)31/h2-10,12-13H,11H2,1H3,(H2,24,31)(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 40n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015941
PNG
(CHEMBL3260622 | USRE47141, Example 46)
Show SMILES COc1ccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)cc1OC
Show InChI InChI=1S/C24H23N7O2/c1-15-5-4-6-18(28-15)24-23(16-7-10-22-26-14-27-31(22)13-16)29-21(30-24)12-25-17-8-9-19(32-2)20(11-17)33-3/h4-11,13-14,25H,12H2,1-3H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 44.2n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015698
PNG
(CHEMBL3260602 | USRE47141, Example 35)
Show SMILES CC(C)c1ccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)cc1
Show InChI InChI=1S/C25H25N7/c1-16(2)18-7-10-20(11-8-18)26-13-22-30-24(19-9-12-23-27-15-28-32(23)14-19)25(31-22)21-6-4-5-17(3)29-21/h4-12,14-16,26H,13H2,1-3H3,(H,30,31)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 46n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015836
PNG
(CHEMBL3260612 | USRE47141, Example 79)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccc(NS(C)(=O)=O)cc2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H22N8O2S/c1-15-4-3-5-19(27-15)23-22(16-6-11-21-25-14-26-31(21)13-16)28-20(29-23)12-24-17-7-9-18(10-8-17)30-34(2,32)33/h3-11,13-14,24,30H,12H2,1-2H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 46.6n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015699
PNG
(CHEMBL3260603 | USRE47141, Example 44)
Show SMILES COc1ccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)cc1
Show InChI InChI=1S/C23H21N7O/c1-15-4-3-5-19(27-15)23-22(16-6-11-21-25-14-26-30(21)13-16)28-20(29-23)12-24-17-7-9-18(31-2)10-8-17/h3-11,13-14,24H,12H2,1-2H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 48.1n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM304158
PNG
(USRE47141, Example 140)
Show SMILES CN(Cc1nc(c([nH]1)-c1cccc(C)n1)-c1ccc2ncnn2c1)c1ccccc1F
Show InChI InChI=1S/C23H20FN7/c1-15-6-5-8-18(27-15)23-22(16-10-11-21-25-14-26-31(21)12-16)28-20(29-23)13-30(2)19-9-4-3-7-17(19)24/h3-12,14H,13H2,1-2H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 49.8n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM304130
PNG
(USRE47141, Example 50)
Show SMILES COCc1ccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)cc1
Show InChI InChI=1S/C24H23N7O/c1-16-4-3-5-20(28-16)24-23(18-8-11-22-26-15-27-31(22)13-18)29-21(30-24)12-25-19-9-6-17(7-10-19)14-32-2/h3-11,13,15,25H,12,14H2,1-2H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 50.7n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015747
PNG
(CHEMBL3260608 | USRE47141, Example 67)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccc(cc2)C(N)=O)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H20N8O/c1-14-3-2-4-18(28-14)22-21(16-7-10-20-26-13-27-31(20)12-16)29-19(30-22)11-25-17-8-5-15(6-9-17)23(24)32/h2-10,12-13,25H,11H2,1H3,(H2,24,32)(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 54.6n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015841
PNG
(CHEMBL3260617 | USRE47141, Example 45)
Show SMILES COc1cccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)c1OC
Show InChI InChI=1S/C24H23N7O2/c1-15-6-4-7-17(28-15)23-22(16-10-11-21-26-14-27-31(21)13-16)29-20(30-23)12-25-18-8-5-9-19(32-2)24(18)33-3/h4-11,13-14,25H,12H2,1-3H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 57.5n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015815
PNG
(CHEMBL3260610 | USRE47141, Example 71)
Show SMILES CC(=O)c1ccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)cc1
Show InChI InChI=1S/C24H21N7O/c1-15-4-3-5-20(28-15)24-23(18-8-11-22-26-14-27-31(22)13-18)29-21(30-24)12-25-19-9-6-17(7-10-19)16(2)32/h3-11,13-14,25H,12H2,1-2H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 59.1n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015700
PNG
(CHEMBL3260604 | USRE47141, Example 53)
Show SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccc(OC(F)(F)F)cc2)nc1-c1ccc2ncnn2c1
Show InChI InChI=1S/C23H18F3N7O/c1-14-3-2-4-18(30-14)22-21(15-5-10-20-28-13-29-33(20)12-15)31-19(32-22)11-27-16-6-8-17(9-7-16)34-23(24,25)26/h2-10,12-13,27H,11H2,1H3,(H,31,32)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 60.1n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM50015822
PNG
(CHEMBL3260611 | USRE47141, Example 73)
Show SMILES COC(=O)c1ccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3ncnn3c2)cc1
Show InChI InChI=1S/C24H21N7O2/c1-15-4-3-5-19(28-15)23-22(17-8-11-21-26-14-27-31(21)13-17)29-20(30-23)12-25-18-9-6-16(7-10-18)24(32)33-2/h3-11,13-14,25H,12H2,1-2H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 78n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM304159
PNG
(USRE47141, Example 141)
Show SMILES CN(Cc1nc(c([nH]1)-c1cccc(C)n1)-c1ccc2ncnn2c1)c1cccc(c1)C#N
Show InChI InChI=1S/C24H20N8/c1-16-5-3-8-20(28-16)24-23(18-9-10-22-26-15-27-32(22)13-18)29-21(30-24)14-31(2)19-7-4-6-17(11-19)12-25/h3-11,13,15H,14H2,1-2H3,(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 118n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens)
BDBM304160
PNG
(USRE47141, Example 142)
Show SMILES CN(Cc1nc(c([nH]1)-c1cccc(C)n1)-c1ccc2ncnn2c1)c1cccc(c1)C(N)=O
Show InChI InChI=1S/C24H22N8O/c1-15-5-3-8-19(28-15)23-22(17-9-10-21-26-14-27-32(21)12-17)29-20(30-23)13-31(2)18-7-4-6-16(11-18)24(25)33/h3-12,14H,13H2,1-2H3,(H2,25,33)(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 153n/an/an/an/an/an/a



EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

US Patent


Assay Description
ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...


US Patent USRE47141 (2018)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%