Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CDK2/CycE (298/298 = 100%)† (Homo sapiens (Human)) | BDBM7604![]() (2-[(2-bromo-4-methylphenyl)[6-({4-[3-(dimethylamin...) | PDB UniProtKB/SwissProt GoogleScholar | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description The kinase activity was assayed using an in vitro scintillation proximity assay (SPA) for measuring incorporation of [gamma-33P] ATP into GST-Rb. | Bioorg Med Chem Lett 13: 2955-60 (2003) Article DOI: 10.1016/s0960-894x(03)00202-6 BindingDB Entry DOI: 10.7270/Q2FJ2F1R | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |