Affinity DataKi: 6.20nMAssay Description:Inhibition of HMG-CoA Reductase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of rat microsomal HMGCoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against 3-hydroxy-3-methylglutaryl-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20nM EC50: 2.5nMpH: 7.0 T: 37°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
Affinity DataIC50: 11.6nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant HMG-CoA reductase (unknown origin) after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
University of Chinese Academy of Sciences
Curated by ChEMBL
University of Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 930nMAssay Description:Inhibition of pig liver microsomal HMG-CoA reductase by colorimetric methodMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
University of Chinese Academy of Sciences
Curated by ChEMBL
University of Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 3.21E+4nMAssay Description:Inhibition of HMG-CoA reductase in pig liver microsomes using HMG-CoA as substrate preincubated for 5 mins followed by NADPH addition measured after ...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
University of Chinese Academy of Sciences
Curated by ChEMBL
University of Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 3.21E+4nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair