Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cathepsin G (235/235 = 100%)† (Homo sapiens (Human)) | BDBM50139758![]() ((2-Naphthalen-2-yl-1-naphthalen-1-yl-2-oxo-ethyl)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Inhibitory activity of the compound against human Cathepsin G | J Med Chem 47: 769-87 (2004) Article DOI: 10.1021/jm030493t BindingDB Entry DOI: 10.7270/Q2251HN2 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |