Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycogen Phosphorylase (PYGL) (847/847 = 100%)† (Homo sapiens (Human)) | BDBM50136446![]() (1-{(S)-2-[(5-Chloro-1H-indole-2-carbonyl)-amino]-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | 7.2 | 22 |
Pfizer Inc | Assay Description Human liver glycogen phsphorylase (HLGP) activity was measured in the direction of glycogen synthesis by the release of phosphate from glucose-1-phos... | Chem Biol 7: 677-82 (2000) Article DOI: 10.1016/S1074-5521(00)00004-1 BindingDB Entry DOI: 10.7270/Q2H41PT2 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Glycogen Phosphorylase (PYGL) (847/847 = 100%)† (Homo sapiens (Human)) | BDBM50136446![]() (1-{(S)-2-[(5-Chloro-1H-indole-2-carbonyl)-amino]-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibitory concentration against recombinant human liver glycogen phosphorylase a (HLGPa) | Bioorg Med Chem Lett 13: 4385-8 (2003) Article DOI: 10.1016/j.bmcl.2003.09.022 BindingDB Entry DOI: 10.7270/Q2S75FQV | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Liver glycogen phosphorylase (803/848 = 95%)† (Rattus norvegicus) | BDBM10849![]() (1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-d...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 6.48E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibitory concentration against rat liver glycogen phosphorylase | Bioorg Med Chem Lett 15: 4944-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.026 BindingDB Entry DOI: 10.7270/Q27M08R5 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |