Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) for PDB: 1LHC
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288406(1-(2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2...)
Affinity DataKi:  0.0400nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50451005(CHEMBL290376 | DuP-714)
Affinity DataKi:  0.0410nMAssay Description:Inhibition constant for binding with thrombin was determinedMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288406(1-(2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2...)
Affinity DataKi:  0.0410nMAssay Description:In vitro for inhibition of thrombin.More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50451005(CHEMBL290376 | DuP-714)
Affinity DataKi:  0.0420nMAssay Description:Inhibition of Coagulation factor IIMore data for this Ligand-Target Pair
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50288406(1-(2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2...)
Affinity DataKi:  55nMAssay Description:Concentration necessary to double time for clot formation induced by bovine thrombinMore data for this Ligand-Target Pair