Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fatty acid-binding protein 4 (FABP4) (120/131 = 92%)† (Homo sapiens (Human)) | BDBM50150484![]() ((Z)-9-octadecenoic acid | (Z)-Octadec-9-enoic acid...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 185 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Displacement of 1,8-ANS from aFABP by fluorescence based-assay | Bioorg Med Chem Lett 17: 3511-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.044 BindingDB Entry DOI: 10.7270/Q24B3119 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Fatty acid-binding protein 4 (FABP4) (120/131 = 92%)† (Homo sapiens (Human)) | BDBM50150484![]() ((Z)-9-octadecenoic acid | (Z)-Octadec-9-enoic acid...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Displacement of 1,8-ANS from His6-tagged FABP4 (unknown origin) expressed in Escherichia coli BL21(DE3) cells by fluorescence assay | Bioorg Med Chem 24: 4310-4317 (2016) Article DOI: 10.1016/j.bmc.2016.07.022 BindingDB Entry DOI: 10.7270/Q2NC634M | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Fatty acid-binding protein 4 (FABP4) (120/131 = 92%)† (Homo sapiens (Human)) | BDBM50150484![]() ((Z)-9-octadecenoic acid | (Z)-Octadec-9-enoic acid...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 2.61E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Displacement of 8-anilino-1-naphthalene-sulfonic acid from human His-FABP4 expressed in Escherichia coli BL21 (DE3) cells after 3 mins | Bioorg Med Chem Lett 20: 3675-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.095 BindingDB Entry DOI: 10.7270/Q2CV4HXG | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |