Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydrofolate reductase (162/162 = 100%)† (Lactobacillus casei) | BDBM18069![]() (5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 132 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pomona College Curated by ChEMBL | Assay Description Inhibitory activity against Lactobacillus casei dihydrofolate reductase | J Med Chem 32: 1895-905 (1989) Article DOI: 10.1021/jm00128a035 BindingDB Entry DOI: 10.7270/Q2QR4ZB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (162/162 = 100%)† (Lactobacillus casei) | BDBM18069![]() (5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 132 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against dihydrofolate reductase (DHFR) from Lactobacillus casei (expressed as log 1/Kiapp) | J Med Chem 25: 777-84 (1982) Article DOI: 10.1021/jm00349a003 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (162/162 = 100%)† (Lactobacillus casei) | BDBM18069![]() (5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University Curated by ChEMBL | Assay Description Inhibitory activity against Dihydrofolate reductase from Lactobacillus casei (lcDHFR) | J Med Chem 41: 3426-34 (1998) Article DOI: 10.1021/jm980081y BindingDB Entry DOI: 10.7270/Q27H1HQZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (162/162 = 100%)† (Lactobacillus casei) | BDBM18069![]() (5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 103 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University Curated by ChEMBL | Assay Description Inhibitory activity against Dihydrofolate reductase from Lactobacillus casei | J Med Chem 38: 1778-85 (1995) Article DOI: 10.1021/jm00010a022 BindingDB Entry DOI: 10.7270/Q2FB520T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (162/162 = 100%)† (Lactobacillus casei) | BDBM18069![]() (5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of Lactobacillus casei DHFR | J Med Chem 50: 3283-9 (2007) Article DOI: 10.1021/jm0701977 BindingDB Entry DOI: 10.7270/Q2TH8MCN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (162/162 = 100%)† (Lactobacillus casei) | BDBM18069![]() (5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University Curated by ChEMBL | Assay Description Compound was evaluated as inhibitor of Lactobacillus casei Dihydrofolate reductase | J Med Chem 46: 591-600 (2003) Article DOI: 10.1021/jm0203534 BindingDB Entry DOI: 10.7270/Q2JQ11RG | |||||||||||
More data for this Ligand-Target Pair |