Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-hexosaminidase subunit beta (Hex B) (58/58 = 100%)† (Homo sapiens (Human)) | BDBM50327038![]() ((3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-5,6,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB PubMed | 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Competitive inhibition of human beta-N-acetyl-D-hexosaminidase-B using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate assessed as re... | ACS Med Chem Lett 4: 527-31 (2013) BindingDB Entry DOI: 10.7270/Q2HX1GMT | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Beta-hexosaminidase subunit beta (Hex B) (58/58 = 100%)† (Homo sapiens (Human)) | BDBM50327038![]() ((3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-5,6,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New Jersey Curated by ChEMBL | Assay Description Inhibition of human beta hexosaminidase | Bioorg Med Chem Lett 18: 2944-7 (2008) Article DOI: 10.1016/j.bmcl.2008.03.067 BindingDB Entry DOI: 10.7270/Q2GH9JVC | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |