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Report error Found 3 Enz. Inhib. hit(s) for PDB: 1PL6
TargetSorbitol dehydrogenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50102723(4-(2-Hydroxymethyl-pyrimidin-4-yl)-piperazine-1-su...)
Affinity DataIC50:  240nMAssay Description:Concentration required for 50% in vitro inhibition of recombinant human sorbitol dehydrogenase (h-SDH)More data for this Ligand-Target Pair
TargetSorbitol dehydrogenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50102723(4-(2-Hydroxymethyl-pyrimidin-4-yl)-piperazine-1-su...)
Affinity DataIC50:  246nMAssay Description:In vitro inhibitory activity against human SDHMore data for this Ligand-Target Pair
TargetSorbitol dehydrogenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50102723(4-(2-Hydroxymethyl-pyrimidin-4-yl)-piperazine-1-su...)
Affinity DataIC50:  1.00E+3nMAssay Description:Concentration required for inhibitory activity against human sorbitol dehydrogenase (SDH)More data for this Ligand-Target Pair