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Report error Found 3 Enz. Inhib. hit(s) for PDB: 1PXL
LigandPNGBDBM8049(2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 20 | 4...)
Affinity DataKi:  290nM ΔG°:  -37.9kJ/molepH: 7.4 T: 30°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 100 uM ATP/ [gamma-32P...More data for this Ligand-Target Pair
LigandPNGBDBM8049(2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 20 | 4...)
Affinity DataIC50:  290nMAssay Description:In vitro inhibition assay using human recombinant CDK2 and human recombinant cyclin A2.More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Human)
Cyclacel

LigandPNGBDBM8049(2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 20 | 4...)
Affinity DataIC50:  290nMAssay Description:In vitro inhibition assay using human recombinant CDK2 and human recombinant cyclin A2.More data for this Ligand-Target Pair