Found 12 Enz. Inhib. hit(s) for PDB: 1RT1 TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Oxford University
Curated by ChEMBL
Oxford University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibitory activity of the compound against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
3D Structure (crystal)TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Oxford University
Curated by ChEMBL
Oxford University
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration required to inhibit the HIV-1 reverse transcriptase activityMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University Of Rome
Sapienza University Of Rome
Affinity DataIC50: 40nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University Of Rome
Sapienza University Of Rome
Affinity DataIC50: 40nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University Of Rome
Sapienza University Of Rome
Affinity DataIC50: 40nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Oxford University
Curated by ChEMBL
Oxford University
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of purified recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Oxford University
Curated by ChEMBL
Oxford University
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against recombinant HIV-1 reverse transcriptase (rRT)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Oxford University
Curated by ChEMBL
Oxford University
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay systemMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Oxford University
Curated by ChEMBL
Oxford University
Curated by ChEMBL
Affinity DataEC50: 4nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree centigradeMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Oxford University
Curated by ChEMBL
Oxford University
Curated by ChEMBL
Affinity DataEC50: 4.20nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Oxford University
Curated by ChEMBL
Oxford University
Curated by ChEMBL
Affinity DataEC50: 2nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Oxford University
Curated by ChEMBL
Oxford University
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Effective concentration required against L100I mutant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
