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Found 4 Enz. Inhib. hit(s) for PDB: 1S3E
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Emory University

LigandPNGBDBM10799((3R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-...)
Affinity DataKi:  1.70E+4nM ΔG°:  -27.2kJ/molepH: 7.5 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically at 316 nm and 250 nm using kynuramine and benzylamine as substrates, respectively. ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Emory University

LigandPNGBDBM10799((3R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-...)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition constant against human recombinant Monoamine oxidase-B More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10799((3R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10798(3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-5-ol ...)
Affinity DataIC50:  600nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair