Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
XIAP-BIR3 (117/117 = 100%)† (Homo sapiens (Human)) | BDBM13166![]() ((2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)p...) | PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | Purchase DrugBank MMDB PC cid PC sid PDB UniChem Similars | DrugBank MMDB PDB Article PubMed | n/a | n/a | n/a | 12 | n/a | n/a | n/a | 7.4 | 22 |
Abbott Laboratories | Assay Description A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari... | J Med Chem 47: 4417-26 (2004) Article DOI: 10.1021/jm040037k BindingDB Entry DOI: 10.7270/Q27M065Q | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |