Affinity Data by PDB ID

PDB code 1UY8

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Heat Shock Protein 90 (Hsp90) (196/213 = 92%)^† (Homo sapiens (Human))	BDBM15376 (9-butyl-8-(3-methoxybenzyl)-9H-purin-6-amine \| 9-b...) Show SMILES CCCCn1c(Cc2cccc(OC)c2)nc2c(N)ncnc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar	CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
RiboTargets Ltd Curated by ChEMBL					Assay Description Inhibition of ATP-ase activity in human colon tumour cell line (HCT116)				Bioorg Med Chem Lett 14: 325-8 (2003) Article DOI: 10.1016/j.bmcl.2003.11.011 BindingDB Entry DOI: 10.7270/Q2P55MX0
RiboTargets Ltd Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output