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Found 3 Enz. Inhib. hit(s) for PDB: 1X88
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198309((S)-4-(3-Hydroxy-phenyl)-6-methyl-2-thioxo-1,2,3,4...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro inhibitory concentration towards kinesin spindle protein activity of ATP hydrolysis in the presence of microtubules measured by ATPase assay...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198309((S)-4-(3-Hydroxy-phenyl)-6-methyl-2-thioxo-1,2,3,4...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198309((S)-4-(3-Hydroxy-phenyl)-6-methyl-2-thioxo-1,2,3,4...)
Affinity DataIC50:  2.07E+4nMpH: 6.8 T: 2°CAssay Description:The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.More data for this Ligand-Target Pair