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PDB code 1XL1

Compile Data Set for Download or QSAR

Identical Ligands in BindingDB

Found 9 hits Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen phosphorylase, muscle form

  (842/842 = 100%)
(Oryctolagus cuniculus (rabbit))
BDBM50295860
PNG
((2R,3R,4S,5S,6R)-2-(benzo[d]thiazol-2-yl)-6-(hydro...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1nc2ccccc2s1
Show InChI InChI=1/C13H15NO5S/c15-5-7-9(16)10(17)11(18)12(19-7)13-14-6-3-1-2-4-8(6)20-13/h1-4,7,9-12,15-18H,5H2/t7-,9-,10+,11-,12-/s2
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7.60E+4n/an/an/an/an/an/an/an/a



University of Debrecen

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase b


Eur J Med Chem 76: 567-79 (2014)


Article DOI: 10.1016/j.ejmech.2014.02.041
BindingDB Entry DOI: 10.7270/Q2ZP47N4
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glycogen phosphorylase, muscle form

  (842/842 = 100%)
(Oryctolagus cuniculus (rabbit))
BDBM50295860
PNG
((2R,3R,4S,5S,6R)-2-(benzo[d]thiazol-2-yl)-6-(hydro...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1nc2ccccc2s1
Show InChI InChI=1/C13H15NO5S/c15-5-7-9(16)10(17)11(18)12(19-7)13-14-6-3-1-2-4-8(6)20-13/h1-4,7,9-12,15-18H,5H2/t7-,9-,10+,11-,12-/s2
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7.60E+4n/an/an/an/an/an/an/an/a



University of Debrecen

Curated by ChEMBL


Assay Description
Competitive inhibition of rabbit muscle glycogen phosphorylase-b using glucose-1-phosphate as substrate preincubated with glycogen for 15 mins follow...


ACS Med Chem Lett 6: 1215-9 (2015)


Article DOI: 10.1021/acsmedchemlett.5b00361
BindingDB Entry DOI: 10.7270/Q2W37Z56
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glycogen phosphorylase, muscle form

  (842/842 = 100%)
(Oryctolagus cuniculus (rabbit))
BDBM50295860
PNG
((2R,3R,4S,5S,6R)-2-(benzo[d]thiazol-2-yl)-6-(hydro...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1nc2ccccc2s1
Show InChI InChI=1/C13H15NO5S/c15-5-7-9(16)10(17)11(18)12(19-7)13-14-6-3-1-2-4-8(6)20-13/h1-4,7,9-12,15-18H,5H2/t7-,9-,10+,11-,12-/s2
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7.60E+4n/an/an/an/an/an/an/an/a



Egypt National Research Centre

Curated by ChEMBL


Assay Description
Inhibition of rabbit skeletal muscle glycogen phosphorylase b assessed as inorganic phosphate release using glucose-1-phosphate as substrate by doubl...


Bioorg Med Chem 24: 5423-5430 (2016)


Article DOI: 10.1016/j.bmc.2016.08.069
BindingDB Entry DOI: 10.7270/Q26D5VZD
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glycogen phosphorylase, muscle form

  (842/842 = 100%)
(Oryctolagus cuniculus (rabbit))
BDBM50295860
PNG
((2R,3R,4S,5S,6R)-2-(benzo[d]thiazol-2-yl)-6-(hydro...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1nc2ccccc2s1
Show InChI InChI=1/C13H15NO5S/c15-5-7-9(16)10(17)11(18)12(19-7)13-14-6-3-1-2-4-8(6)20-13/h1-4,7,9-12,15-18H,5H2/t7-,9-,10+,11-,12-/s2
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7.60E+4n/an/an/an/an/an/an/an/a



University of Thessaly

Curated by ChEMBL


Assay Description
Competitive inhibition of rabbit muscle glycogen phosphorylase-b in presence of varying levels of glucose-1-phosphate and constant concentration of g...


Eur J Med Chem 123: 737-745 (2016)


Article DOI: 10.1016/j.ejmech.2016.06.049
BindingDB Entry DOI: 10.7270/Q2TT4SXG
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glycogen phosphorylase, muscle form

  (842/842 = 100%)
(Oryctolagus cuniculus (rabbit))
BDBM50295860
PNG
((2R,3R,4S,5S,6R)-2-(benzo[d]thiazol-2-yl)-6-(hydro...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1nc2ccccc2s1
Show InChI InChI=1/C13H15NO5S/c15-5-7-9(16)10(17)11(18)12(19-7)13-14-6-3-1-2-4-8(6)20-13/h1-4,7,9-12,15-18H,5H2/t7-,9-,10+,11-,12-/s2
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7.60E+4n/an/an/an/an/an/an/an/a



University of Debrecen

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase b


ACS Med Chem Lett 4: 612-5 (2013)


Article DOI: 10.1021/ml4001529
BindingDB Entry DOI: 10.7270/Q2X068FD
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glycogen phosphorylase, muscle form

  (842/842 = 100%)
(Oryctolagus cuniculus (rabbit))
BDBM50295860
PNG
((2R,3R,4S,5S,6R)-2-(benzo[d]thiazol-2-yl)-6-(hydro...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1nc2ccccc2s1
Show InChI InChI=1/C13H15NO5S/c15-5-7-9(16)10(17)11(18)12(19-7)13-14-6-3-1-2-4-8(6)20-13/h1-4,7,9-12,15-18H,5H2/t7-,9-,10+,11-,12-/s2
PDB
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KEGG

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GoogleScholar
CHEBI
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7.60E+4n/an/an/an/an/an/an/an/a



University of Debrecen

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase b


Bioorg Med Chem 17: 4773-85 (2009)


Article DOI: 10.1016/j.bmc.2009.04.036
BindingDB Entry DOI: 10.7270/Q2Q52PPV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glycogen phosphorylase, muscle form

  (842/842 = 100%)
(Oryctolagus cuniculus (rabbit))
BDBM50295860
PNG
((2R,3R,4S,5S,6R)-2-(benzo[d]thiazol-2-yl)-6-(hydro...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1nc2ccccc2s1
Show InChI InChI=1/C13H15NO5S/c15-5-7-9(16)10(17)11(18)12(19-7)13-14-6-3-1-2-4-8(6)20-13/h1-4,7,9-12,15-18H,5H2/t7-,9-,10+,11-,12-/s2
PDB
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KEGG

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GoogleScholar
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2.29E+5n/an/an/an/an/an/an/an/a



University of Thessaly

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase-b


Eur J Med Chem 123: 737-745 (2016)


Article DOI: 10.1016/j.ejmech.2016.06.049
BindingDB Entry DOI: 10.7270/Q2TT4SXG
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glycogen phosphorylase, muscle form

  (842/842 = 100%)
(Oryctolagus cuniculus (rabbit))
BDBM50295860
PNG
((2R,3R,4S,5S,6R)-2-(benzo[d]thiazol-2-yl)-6-(hydro...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1nc2ccccc2s1
Show InChI InChI=1/C13H15NO5S/c15-5-7-9(16)10(17)11(18)12(19-7)13-14-6-3-1-2-4-8(6)20-13/h1-4,7,9-12,15-18H,5H2/t7-,9-,10+,11-,12-/s2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEBI
CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
PDB
Article
PubMed
2.29E+5n/an/an/an/an/an/an/an/a



Egypt National Research Centre

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase b using alpha-D-glucose-1-phosphate as substrate


Bioorg Med Chem 24: 5423-5430 (2016)


Article DOI: 10.1016/j.bmc.2016.08.069
BindingDB Entry DOI: 10.7270/Q26D5VZD
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glycogen phosphorylase, muscle form

  (842/842 = 100%)
(Oryctolagus cuniculus (rabbit))
BDBM50295860
PNG
((2R,3R,4S,5S,6R)-2-(benzo[d]thiazol-2-yl)-6-(hydro...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1nc2ccccc2s1
Show InChI InChI=1/C13H15NO5S/c15-5-7-9(16)10(17)11(18)12(19-7)13-14-6-3-1-2-4-8(6)20-13/h1-4,7,9-12,15-18H,5H2/t7-,9-,10+,11-,12-/s2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEBI
CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
PDB
Article
PubMed
2.29E+5n/an/an/an/an/an/an/an/a



University of Debrecen

Curated by ChEMBL


Assay Description
Inhibition of rabbit muscle glycogen phosphorylase-b


ACS Med Chem Lett 6: 1215-9 (2015)


Article DOI: 10.1021/acsmedchemlett.5b00361
BindingDB Entry DOI: 10.7270/Q2W37Z56
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)

Search BindingMOAD for More Affinity Data:

* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
Identities from BLAST output