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Report error Found 3 Enz. Inhib. hit(s) for PDB: 1YI3
TargetSerine/threonine-protein kinase pim-1(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)
Affinity DataIC50:  820nMAssay Description:Inhibition of PIM1 in the presence of 20uM ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of full length human Pim-2 kinase expressed in Escherichia coli BL21/DE3 using S6 peptide as substrate by coupled enzyme assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)
Affinity DataIC50:  4.00E+3nMpH: 7.6 T: 30°CAssay Description:A coupled-enzyme assay was used to quantify the ADP generated in the kinase reaction with S6 peptide (RRRLSSLRA) as the phosphoacceptorsubstrate.More data for this Ligand-Target Pair