Affinity Data by PDB ID

PDB code 1YKR

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
CDK2/CycE (298/298 = 100%)^† (Homo sapiens (Human))	BDBM6670 (4-({6-[(2,6-dichlorophenyl)carbonyl]imidazo[1,2-a]...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar	DrugBank MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	7.0	22
Eli Lilly and Company					Assay Description In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....				Bioorg Med Chem Lett 15: 1943-7 (2005) Article DOI: 10.1016/j.bmcl.2005.01.052 BindingDB Entry DOI: 10.7270/Q23F4MTR
Eli Lilly and Company					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output