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Found 4 Enz. Inhib. hit(s) for PDB: 1Z3N
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
The Institute For Diabetes Discovery

LigandPNGBDBM16469(2-{3-[(4,5,7-trifluoro-1,3-benzothiazol-2-yl)methy...)
Affinity DataIC50:  5nMpH: 6.6 T: 2°CAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappear...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM16469(2-{3-[(4,5,7-trifluoro-1,3-benzothiazol-2-yl)methy...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Wistar rat lens aldose reductase using D,L-glyceraldehyde as substrate incubated for 1 min measured for 4 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
The Institute For Diabetes Discovery

LigandPNGBDBM16469(2-{3-[(4,5,7-trifluoro-1,3-benzothiazol-2-yl)methy...)
Affinity DataIC50:  5nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
The Institute For Diabetes Discovery

LigandPNGBDBM16469(2-{3-[(4,5,7-trifluoro-1,3-benzothiazol-2-yl)methy...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of human recombinant aldose reductase 1 after 10 mins by spectrophotometry analysisMore data for this Ligand-Target Pair