Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphodiesterase 7 (353/353 = 100%)† (Homo sapiens (Human)) | BDBM50027176![]() (2-Acetoxy-Benzoic Acid | 3-Isobutyl-Methylxanthine...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Monash University (Parkville Campus) Curated by ChEMBL | Assay Description Inhibition of human phosphodiesterase 7 | J Med Chem 48: 3449-62 (2005) Article DOI: 10.1021/jm040217u BindingDB Entry DOI: 10.7270/Q21G0N2H | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
3',5'-cyclic phosphodiesterase (353/353 = 100%)† (Homo sapiens (Human)) | BDBM50027176![]() (2-Acetoxy-Benzoic Acid | 3-Isobutyl-Methylxanthine...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | 8.56E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College Curated by ChEMBL | Assay Description Inhibition of recombinant human PDE7A using cAMP as substrate after 10 mins by PDE-Glo Phosphodiesterase Assay | Eur J Med Chem 158: 517-533 (2018) BindingDB Entry DOI: 10.7270/Q2TB19K7 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
3',5'-cyclic phosphodiesterase (353/353 = 100%)† (Homo sapiens (Human)) | BDBM50027176![]() (2-Acetoxy-Benzoic Acid | 3-Isobutyl-Methylxanthine...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | Purchase DrugBank PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | 8.56E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Curated by ChEMBL | Assay Description Inhibition of human GST-tagged PDE7A expressed in baculovirus infected Sf9 insect cells using cAMP as substrate after 10 mins by PDE-Glo Phosphodiest... | Eur J Med Chem 146: 381-394 (2018) BindingDB Entry DOI: 10.7270/Q2XD1496 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |