Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-secretase 1 (402/404 > 99%)† (Homo sapiens (Human)) | BDBM16024![]() (3-benzoyl-N-[(2S,3R)-4-(cyclopropylamino)-3-hydrox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 98 | n/a | n/a | n/a | n/a | 4.5 | 22 |
Merck Research Laboratories | Assay Description The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ... | Bioorg Med Chem Lett 16: 641-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.032 BindingDB Entry DOI: 10.7270/Q28S4N5N | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |