Affinity Data by PDB ID

PDB code 2BXR

Identical Ligands in BindingDB

Found 86 hits Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Padova Curated by ChEMBL					Assay Description Irreversible inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot ...				Eur J Med Chem 70: 88-101 (2013) BindingDB Entry DOI: 10.7270/Q2T156MV
University of Padova Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine Oxidase Type A (MAO-A) (464/527 = 88%)^† (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	54	-43.3	n/a	n/a	n/a	n/a	n/a	7.4	38
Sapienza University of Rome					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 50: 922-31 (2007) Article DOI: 10.1021/jm060882y BindingDB Entry DOI: 10.7270/Q2GH9G61
Sapienza University of Rome					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (464/527 = 88%)^† (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibitory activity against monoamine oxidase A in isolated bovine brain mitochondria				J Med Chem 46: 917-20 (2003) Article DOI: 10.1021/jm0256124 BindingDB Entry DOI: 10.7270/Q20V8C52
Sapienza University of Rome Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (464/527 = 88%)^† (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of bovine brain mitochondrial MAO-A by fluorometric assay				Bioorg Med Chem 16: 9729-40 (2008) Article DOI: 10.1016/j.bmc.2008.09.072 BindingDB Entry DOI: 10.7270/Q20001ZK
Sapienza University of Rome Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (464/527 = 88%)^† (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Inhibition of bovine brain MAOA using kinuramine as substrate preincubated for 30 mins prior to substrate addition measured after 30 mins by fluorome...				J Med Chem 55: 10424-36 (2012) Article DOI: 10.1021/jm301014y BindingDB Entry DOI: 10.7270/Q2G73FWJ
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (459/525 = 87%)^† (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hacettepe University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver homogenate after 60 mins by Lineweaver-Burk plot				Bioorg Med Chem 17: 675-89 (2009) Article DOI: 10.1016/j.bmc.2008.11.068 BindingDB Entry DOI: 10.7270/Q2BG2NWT
Hacettepe University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	0.00490	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibition of human monoamine oxidase A				Bioorg Med Chem 18: 7675-99 (2010) Article DOI: 10.1016/j.bmc.2010.07.034 BindingDB Entry DOI: 10.7270/Q2DF6S69
Pfizer Inc Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (459/525 = 87%)^† (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.420	n/a	n/a	n/a	n/a	n/a	n/a
General Hospital of PLA Curated by ChEMBL					Assay Description Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assay				Bioorg Med Chem Lett 22: 3343-8 (2012) Article DOI: 10.1016/j.bmcl.2012.02.090 BindingDB Entry DOI: 10.7270/Q2JW8FWM
General Hospital of PLA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
R-Tech Ueno, Ltd. US Patent					Assay Description The compounds of the present invention obtained in the Production Examples were examined for the inhibitory effect on human monoamineoxydase enzymes ...				US Patent US9603833 (2017) BindingDB Entry DOI: 10.7270/Q2W37ZCW
R-Tech Ueno, Ltd. US Patent					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (459/525 = 87%)^† (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro Inhibitory activity of Monoamine oxidase at rat hyphalamic mitochondrial 5-HT by displacing 2.5 uM of [14C]5-HT (serotonin)				J Med Chem 26: 1036-42 (1983) Article DOI: 10.1021/jm00361a017 BindingDB Entry DOI: 10.7270/Q2K076FV
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
University of the Western Cape Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinolone production using kynuramine as substrate after 20 mins by fluoresce...				Eur J Med Chem 125: 853-864 (2017) Article DOI: 10.1016/j.ejmech.2016.09.041 BindingDB Entry DOI: 10.7270/Q2BP057T
University of the Western Cape Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (459/525 = 87%)^† (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris 7 Curated by ChEMBL					Assay Description In vitro inhibitory activity on rat brain by monoamine oxidase A (MAO-A)				J Med Chem 36: 1157-67 (1993) Article DOI: 10.1021/jm00061a006 BindingDB Entry DOI: 10.7270/Q2765FZP
Universit£ Paris 7 Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
The University of British Columbia Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells using tyramine as substrate preincubated for 1 hr f...				J Med Chem 61: 7043-7064 (2018) BindingDB Entry DOI: 10.7270/Q2VT1VSP
The University of British Columbia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
North-West University Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA expressed in insect cell microsomes using kynuramine as substrate after 20 mins by fluorescence spectrophotometr...				Bioorg Med Chem Lett 22: 7367-70 (2012) Article DOI: 10.1016/j.bmcl.2012.10.070 BindingDB Entry DOI: 10.7270/Q2CN7526
North-West University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A using kynuramine as substrate measured after 30 mins by fluorescence assay				Bioorg Med Chem 25: 714-726 (2017) Article DOI: 10.1016/j.bmc.2016.11.048 BindingDB Entry DOI: 10.7270/Q21C1ZVW
Sichuan University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A using kynuramine as substrate after 30 mins by fluorescence spectrophotometry				Bioorg Med Chem 24: 2342-51 (2016) Article DOI: 10.1016/j.bmc.2016.04.012 BindingDB Entry DOI: 10.7270/Q21N8316
Sichuan University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A using kynuramine as substrate after 30 mins by fluorescence assay				Bioorg Med Chem 26: 1885-1895 (2018) BindingDB Entry DOI: 10.7270/Q2J67KKZ
Sichuan University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected High 5 insect cells using kynuramine as substrate incubated for 30 mins by sp...				Bioorg Med Chem 25: 1030-1041 (2017) Article DOI: 10.1016/j.bmc.2016.12.013 BindingDB Entry DOI: 10.7270/Q2PR7XZS
Sichuan University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 30 mins by fluorimetric ...				Bioorg Med Chem 25: 1997-2009 (2017) Article DOI: 10.1016/j.bmc.2017.02.027 BindingDB Entry DOI: 10.7270/Q2Q81GBJ
Sichuan University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 30 mins by fluorescence ...				Bioorg Med Chem 26: 1102-1115 (2018) BindingDB Entry DOI: 10.7270/Q2MW2KRT
Sichuan University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate incubated for 30 mins by fluor...				Eur J Med Chem 126: 762-775 (2017) Article DOI: 10.1016/j.ejmech.2016.12.009 BindingDB Entry DOI: 10.7270/Q2NG4SW1
Sichuan University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (459/525 = 87%)^† (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition				Bioorg Med Chem Lett 25: 70-4 (2015) Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH
King Saud University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase A (464/527 = 88%)^† (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Alexandria University Curated by ChEMBL					Assay Description Inhibition of bovine brain mitochondria MAO-A using serotonin substrate after 60 mins by fluorimetric method				Bioorg Med Chem 23: 3574-85 (2015) Article DOI: 10.1016/j.bmc.2015.04.021 BindingDB Entry DOI: 10.7270/Q28K7BVZ
Alexandria University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of Jena Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA				J Med Chem 58: 6710-5 (2015) Article DOI: 10.1021/acs.jmedchem.5b00958 BindingDB Entry DOI: 10.7270/Q2QZ2CRZ
University of Jena Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (464/527 = 88%)^† (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Alexandria University Curated by ChEMBL					Assay Description Inhibition of bovine brain MAO-A preincubated for 60 mins before substrate addition by fluorimetric method				Eur J Med Chem 93: 308-20 (2015) Article DOI: 10.1016/j.ejmech.2015.02.020 BindingDB Entry DOI: 10.7270/Q2VH5QJ9
Alexandria University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Alexandria University Curated by ChEMBL					Assay Description Inhibition of MAOA by spectrophotometry				Eur J Med Chem 45: 4479-89 (2010) Article DOI: 10.1016/j.ejmech.2010.07.008 BindingDB Entry DOI: 10.7270/Q21G0N86
Alexandria University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (464/527 = 88%)^† (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Assiut University Curated by ChEMBL					Assay Description Inhibition of bovine brain mitochondria MAO-A by spectrofluorimetry				Eur J Med Chem 93: 481-91 (2015) Article DOI: 10.1016/j.ejmech.2015.02.039 BindingDB Entry DOI: 10.7270/Q2FX7C5D
Assiut University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Nanyang Normal University Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A using kynuramine as substrate after 30 mins by fluorescence method				Bioorg Med Chem Lett 27: 5046-5052 (2017) Article DOI: 10.1016/j.bmcl.2017.09.057 BindingDB Entry DOI: 10.7270/Q2XS5XTR
Nanyang Normal University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Nanyang Normal University Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 30 mins by fluorescence ...				Bioorg Med Chem 25: 3006-3017 (2017) Article DOI: 10.1016/j.bmc.2017.03.070 BindingDB Entry DOI: 10.7270/Q2F76G04
Nanyang Normal University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect cells using p-tyramine as substrate preincubated for 15 min...				Bioorg Med Chem 25: 633-645 (2017) Article DOI: 10.1016/j.bmc.2016.11.032 BindingDB Entry DOI: 10.7270/Q2HH6N2G
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Xinxiang Medical University Curated by ChEMBL					Assay Description Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assay				Eur J Med Chem 140: 392-402 (2017) BindingDB Entry DOI: 10.7270/Q2HH6NK6
Xinxiang Medical University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (464/527 = 88%)^† (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Manipal College of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Inhibition of MAO-A in bovine brain mitochondria using serotonin as substrate preincubated for 30 mins measured after 30 mins by spectrofluorimetric ...				Bioorg Med Chem Lett 25: 5281-5 (2015) Article DOI: 10.1016/j.bmcl.2015.09.048 BindingDB Entry DOI: 10.7270/Q2M90BH5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of Santiago de Compostela Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as hydrogen peroxide production from p-tyra...				Eur J Med Chem 46: 5838-51 (2011) Article DOI: 10.1016/j.ejmech.2011.09.045 BindingDB Entry DOI: 10.7270/Q2VD6ZVK
University of Santiago de Compostela Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA expressed in BTI-TN-5B1-4 cells by para-tyramine oxidation assay				Bioorg Med Chem 18: 1273-9 (2010) Article DOI: 10.1016/j.bmc.2009.12.029 BindingDB Entry DOI: 10.7270/Q2X63N2Z
Sapienza University of Rome Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A using p-tyramine substrate preincubated for 15 mins before substrate addition measured after 20 mins by fluores...				Eur J Med Chem 62: 745-53 (2013) Article DOI: 10.1016/j.ejmech.2013.01.039 BindingDB Entry DOI: 10.7270/Q2C82BN6
Sun Yat-sen University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A using p-tyramine as substrate incubated for 15 mins prior to substrate addition measured after 20 mins by fluor...				Bioorg Med Chem 23: 3722-9 (2015) Article DOI: 10.1016/j.bmc.2015.04.009 BindingDB Entry DOI: 10.7270/Q2S46TQR
Sun Yat-sen University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA assessed as H2O2 production by Amplex Red reagent-based assay				J Med Chem 55: 8483-92 (2012) Article DOI: 10.1021/jm300978h BindingDB Entry DOI: 10.7270/Q29Z962V
Sun Yat-sen University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.46	n/a	n/a	n/a	n/a	n/a	n/a
University of Santiago de Compostela Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA by fluorimetric method				J Med Chem 51: 6740-51 (2008) Article DOI: 10.1021/jm800656v BindingDB Entry DOI: 10.7270/Q2NV9J3H
University of Santiago de Compostela Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.46	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA				Eur J Med Chem 45: 800-4 (2010) Article DOI: 10.1016/j.ejmech.2009.11.003 BindingDB Entry DOI: 10.7270/Q2CR5TH5
Universit£ di Roma Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.46	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of human MAOA by fluorimetry				Bioorg Med Chem 18: 5715-23 (2010) Article DOI: 10.1016/j.bmc.2010.06.007 BindingDB Entry DOI: 10.7270/Q25D8S19
Sapienza University of Rome Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.46	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento Farmaco Chimico Tecnologico Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA expressed in baculovirus infected BTI insect cells assessed as hydrogen peroxide production after 15 mins by Amp...				Eur J Med Chem 45: 4490-8 (2010) Article DOI: 10.1016/j.ejmech.2010.07.009 BindingDB Entry DOI: 10.7270/Q2FT8M7J
Dipartimento Farmaco Chimico Tecnologico Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.46	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of human MAO-A expressed in baculovirus infected BTI-TN-5B1-4 cells using p-tyramine as substrate incubated for 15 mins prior to substrate...				Eur J Med Chem 58: 405-17 (2012) Article DOI: 10.1016/j.ejmech.2012.10.032 BindingDB Entry DOI: 10.7270/Q20G3M75
Sapienza University of Rome Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.46	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect sells assessed as hydrogen peroxide production by fluorim...				J Med Chem 54: 2155-64 (2011) Article DOI: 10.1021/jm1013709 BindingDB Entry DOI: 10.7270/Q2902435
Sapienza University of Rome Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.46	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA expressed in baculovirus infected insect BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-t...				J Med Chem 53: 6516-20 (2010) Article DOI: 10.1021/jm100120s BindingDB Entry DOI: 10.7270/Q26H4HNW
Sapienza University of Rome Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus-infected BTI-TN-5B1-4 cell microsomes assessed as decrease in H2O2 production using p-...				Bioorg Med Chem 22: 2887-95 (2014) Article DOI: 10.1016/j.bmc.2014.03.042 BindingDB Entry DOI: 10.7270/Q2C53NCP
Sapienza University of Rome Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus infected BT1 cells				Bioorg Med Chem Lett 20: 6479-82 (2010) Article DOI: 10.1016/j.bmcl.2010.09.061 BindingDB Entry DOI: 10.7270/Q2HM59QH
Sapienza University of Rome Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	7.4	n/a
Quaid-i-Azam University					Assay Description The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...				Bioorg Chem 70: 17-26 (2017) Article DOI: 10.1016/j.bioorg.2016.11.004 BindingDB Entry DOI: 10.7270/Q2WM1C7Z
Quaid-i-Azam University					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	7.4	37
Sapienza University of Rome					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 2818-24 (2009) Article DOI: 10.1021/jm801590u BindingDB Entry DOI: 10.7270/Q2X63K8T
Sapienza University of Rome					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Porto Curated by ChEMBL					Assay Description Inhibition of human recombinant microsomal MAOA expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...				Eur J Med Chem 158: 781-800 (2018) BindingDB Entry DOI: 10.7270/Q2F192DM
University of Porto Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected insect BTI-TN-5B1-4 cells assessed as p-tyramine conversion to H2O...				Bioorg Med Chem Lett 23: 5128-30 (2013) BindingDB Entry DOI: 10.7270/Q2WD43H9
Universit£ La Sapienza Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
"G. D'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A using kynuramine as substrate after 20 mins by fluorescence assay				Eur J Med Chem 143: 1543-1552 (2018) BindingDB Entry DOI: 10.7270/Q27H1N3J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (459/525 = 87%)^† (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Government College University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30...				Eur J Med Chem 143: 1373-1386 (2018) BindingDB Entry DOI: 10.7270/Q21V5HHC
Government College University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Porto Curated by ChEMBL					Assay Description Inhibition of human recombinant microsomal MAOA expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...				J Med Chem 60: 7206-7212 (2017) Article DOI: 10.1021/acs.jmedchem.7b00918 BindingDB Entry DOI: 10.7270/Q23B62KQ
University of Porto Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BT1-TN-5B1-4 cells assessed as inhibition of production of hydrogen peroxide ...				Eur J Med Chem 59: 91-100 (2013) Article DOI: 10.1016/j.ejmech.2012.11.006 BindingDB Entry DOI: 10.7270/Q2T43VFR
Sapienza University of Rome Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant microsomal MAO-A expressed in baculovirus infected BTI-TN-5B1-4 cells using p-tyramine as substrate assessed as reduc...				Eur J Med Chem 117: 292-300 (2016) Article DOI: 10.1016/j.ejmech.2016.03.081 BindingDB Entry DOI: 10.7270/Q2JW8GSP
Universit£ di Roma Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Cagliari Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI cells using p-tyramine as substrate after 15 mins by Amplex Red-based flu...				Eur J Med Chem 108: 542-52 (2016) Article DOI: 10.1016/j.ejmech.2015.12.026 BindingDB Entry DOI: 10.7270/Q2GX4DFK
Universit£ degli Studi di Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Magna Gr£cia di Catanzaro Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as inhibition of hydrogen peroxide product...				Eur J Med Chem 48: 284-95 (2012) Article DOI: 10.1016/j.ejmech.2011.12.027 BindingDB Entry DOI: 10.7270/Q2JS9QW8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorio de Quimica Medica (IQOG, CSIC) Curated by ChEMBL					Assay Description Inhibition of human MAO-A expressed in baculovirus infected BTI insect cells preincubated for 15 mins				J Med Chem 57: 10455-63 (2014) Article DOI: 10.1021/jm501501a BindingDB Entry DOI: 10.7270/Q2WS8VX3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A using kynuramine substrate by spectrophotometric assay				J Med Chem 58: 5561-78 (2015) Article DOI: 10.1021/acs.jmedchem.5b00599 BindingDB Entry DOI: 10.7270/Q26T0PCZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as hydrogen peroxide production from p-tyra...				Bioorg Med Chem 18: 5063-70 (2010) Article DOI: 10.1016/j.bmc.2010.05.070 BindingDB Entry DOI: 10.7270/Q22F7PD1
Sapienza University of Rome Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Magna Graecia di Catanzaro Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A assessed as inhibition of production of hydrogen peroxide after 15 mins by Amplex Red fluorimetric method				Bioorg Med Chem Lett 20: 2709-12 (2010) Article DOI: 10.1016/j.bmcl.2010.03.081 BindingDB Entry DOI: 10.7270/Q22V2G80
Universit£ Magna Graecia di Catanzaro Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Anadolu University Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using tyramine as substrate pretreated for 30 mins followed ...				Eur J Med Chem 131: 92-106 (2017) Article DOI: 10.1016/j.ejmech.2017.03.009 BindingDB Entry DOI: 10.7270/Q2MG7RZB
Anadolu University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Sunchon National University Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA using kynuramine as substrate preincubated for 30 mins followed by substrate addition				Bioorg Med Chem Lett 28: 584-588 (2018) BindingDB Entry DOI: 10.7270/Q25T3P2R
Sunchon National University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric ana...				Bioorg Med Chem Lett 22: 4926-9 (2012) Article DOI: 10.1016/j.bmcl.2012.06.058 BindingDB Entry DOI: 10.7270/Q21Z45GF
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A using kynuramine as substrate after 30 mins by fluorescence assay				Bioorg Med Chem Lett 27: 718-722 (2017) Article DOI: 10.1016/j.bmcl.2017.01.050 BindingDB Entry DOI: 10.7270/Q2JM2CX6
Sichuan University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	7.4	n/a
Sichuan University					Assay Description Recombinant human MAO-A and MAO-B (5 mg/mL) were purchased from Sigma-Aldrich, pre-aliquoted and stored at -80 °C. Solutions of test compounds we...				Bioorg Chem 71: 305-314 (2017) Article DOI: 10.1016/j.bioorg.2017.02.016 BindingDB Entry DOI: 10.7270/Q2X9295T
Sichuan University					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human MAOA using p-tyramine as substrate after 30 mins by Amplex red based spectrophotometric analysis				Bioorg Med Chem 23: 6486-96 (2015) Article DOI: 10.1016/j.bmc.2015.08.012 BindingDB Entry DOI: 10.7270/Q2MK6FPP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A using p-tyramine as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by...				Bioorg Med Chem 26: 232-244 (2018) BindingDB Entry DOI: 10.7270/Q2959M4S
Yonsei University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Sunchon National University Curated by ChEMBL					Assay Description Reversible inhibition of recombinant human MAO-A assessed as residual activity using kynuramine as substrate preincubated for 30 mins followed by dia...				Bioorg Med Chem Lett 28: 2403-2407 (2018) BindingDB Entry DOI: 10.7270/Q23R0WCT
Sunchon National University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human MAOA after 1 hr by luminescence assay				J Med Chem 56: 1247-61 (2013) Article DOI: 10.1021/jm301686s BindingDB Entry DOI: 10.7270/Q2SB472H
Universit£ degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human MAOA using p-tyramine as substrate preincubated for 15 mins followed by substrate addition measured after 15 mins by ...				Eur J Med Chem 143: 33-47 (2018) BindingDB Entry DOI: 10.7270/Q2C53PC3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Okayama University Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...				Eur J Med Chem 121: 864-879 (2016) Article DOI: 10.1016/j.ejmech.2015.10.001 BindingDB Entry DOI: 10.7270/Q2B27X8T
Okayama University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Rottapharm S.p.A US Patent					Assay Description Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...				US Patent US8633208 (2014) BindingDB Entry DOI: 10.7270/Q23J3BMD
Rottapharm S.p.A US Patent					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (459/525 = 87%)^† (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Okayama University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver homogenate using [14C]-5HT as substrate preincubated for 30 mins followed by substrate addition measured after 20 mi...				Eur J Med Chem 80: 543-61 (2014) Article DOI: 10.1016/j.ejmech.2014.04.078 BindingDB Entry DOI: 10.7270/Q2BK1DWK
Okayama University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	30.2	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in insect cells assessed as inhibition of kynuramine oxidation after 30 mins by fluorescence assay				J Med Chem 54: 7023-9 (2011) Article DOI: 10.1021/jm200710b BindingDB Entry DOI: 10.7270/Q2765FQJ
Karolinska Institutet Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	189	n/a	n/a	n/a	n/a	n/a	n/a
Hefei University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A using p-tyramine as substrate preincubated for 15 mins followed by substrate addition measured over 15 mins by ...				Eur J Med Chem 145: 588-593 (2018) BindingDB Entry DOI: 10.7270/Q2JD50CJ
Hefei University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	189	n/a	n/a	n/a	n/a	n/a	n/a
Anhui Medical University Curated by ChEMBL					Assay Description Inhibition of recombinant human microsomal MAO-A expressed in baculovirus-infected insect cells using p-tyramine as substrate assessed as H2O2 produc...				Bioorg Med Chem 24: 1741-8 (2016) Article DOI: 10.1016/j.bmc.2016.02.045 BindingDB Entry DOI: 10.7270/Q2T72K99
Anhui Medical University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (459/525 = 87%)^† (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro Inhibitory activity of Monoamine oxidase at rat hyphalamic mitochondrial PEA by displacing 2.5 uM of [14C]PEA (phenethylamine)				J Med Chem 26: 1036-42 (1983) Article DOI: 10.1021/jm00361a017 BindingDB Entry DOI: 10.7270/Q2K076FV
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (459/525 = 87%)^† (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	2.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology Curated by ChEMBL					Assay Description Inhibition of MAOA in rat liver homogenates preincubated for 60 mins				Bioorg Med Chem Lett 18: 6362-8 (2008) Article DOI: 10.1016/j.bmcl.2008.10.084 BindingDB Entry DOI: 10.7270/Q2GT5N1F
Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (459/525 = 87%)^† (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	2.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hacettepe University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver homogenate after 60 mins by residual activity plot				Bioorg Med Chem 17: 675-89 (2009) Article DOI: 10.1016/j.bmc.2008.11.068 BindingDB Entry DOI: 10.7270/Q2BG2NWT
Hacettepe University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (459/525 = 87%)^† (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	2.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hacettepe University Curated by ChEMBL					Assay Description Inhibition of rat liver MAOA after 60 mins pre-incubation				Bioorg Med Chem 15: 5775-86 (2007) Article DOI: 10.1016/j.bmc.2007.06.004 BindingDB Entry DOI: 10.7270/Q2JH3N0R
Hacettepe University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hefei University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human MAOA using p-tyramine as substrate assessed as H2O2 production preincubated for 15 mins followed by substrate additio...				Eur J Med Chem 103: 185-90 (2015) Article DOI: 10.1016/j.ejmech.2015.08.055 BindingDB Entry DOI: 10.7270/Q29C7070
Hefei University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Anhui Medical University Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A using p-tyramine as substrate assessed as production of H2O2 incubated for 15 mins prior to substrate addition ...				Bioorg Med Chem 23: 515-25 (2015) Article DOI: 10.1016/j.bmc.2014.12.010 BindingDB Entry DOI: 10.7270/Q2R2132N
Anhui Medical University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA				J Med Chem 51: 4874-80 (2008) Article DOI: 10.1021/jm800132g BindingDB Entry DOI: 10.7270/Q27P8Z5J
Sapienza University of Rome Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase (flavin-containing) A (527/527 = 100%)^† (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-tyramin...				Eur J Med Chem 46: 4846-52 (2011) Article DOI: 10.1016/j.ejmech.2011.07.017 BindingDB Entry DOI: 10.7270/Q2QV3MXF
Sapienza University of Rome Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (459/525 = 87%)^† (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rat brain mitochondrial Monoamine oxidase				J Med Chem 28: 186-93 (1985) Article DOI: 10.1021/jm00380a007 BindingDB Entry DOI: 10.7270/Q26M3910
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

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Search BindingMOAD for More Affinity Data:

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output