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Report error Found 8 Enz. Inhib. hit(s) for PDB: 2EI8
TargetCoagulation factor X(Rabbit)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataKi:  1.74nMAssay Description:Inhibition of rabbit factor 10a by Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataKi:  2.85nMAssay Description:Inhibition of human factor 10a by Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetCoagulation factor X(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataKi:  8.77nMAssay Description:Inhibition of rat factor 10a by Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataIC50:  2.30nMpH: 7.4 T: 23°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataIC50:  2.30nMpH: 7.4 T: 23°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair