Affinity Data by PDB ID

PDB code 2F3F

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
beta-Secretase (BACE-1) (400/400 = 100%)^† (Homo sapiens (human))	BDBM16088 ((2R,4S)-4-[(4aS,12R,15S,17aS)-15-methyl-14,17-diox...) Show SMILES Show InChI	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	25
Universite de Montreal at Succursale Centre-Ville					Assay Description Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...				J Med Chem 49: 4544-67 (2006) Article DOI: 10.1021/jm060154a BindingDB Entry DOI: 10.7270/Q2RV0KZN
Universite de Montreal at Succursale Centre-Ville					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output