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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dihydroorotate Dehydrogenase (DHODH) (367/367 = 100%)† (Homo sapiens (human)) | BDBM16114 (3-{[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl}t...) | PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet  | DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 44 | n/a | n/a | n/a | n/a | 8.0 | 25 |
4SC AG | Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect... | Bioorg Med Chem Lett 16: 267-70 (2006) | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Dihydroorotate dehydrogenase (367/367 = 100%)† (Homo sapiens (Human)) | BDBM16114 (3-{[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl}t...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 44 | n/a | n/a | n/a | n/a | 8.0 | 30 |
4SC AG | Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect... | J Med Chem 49: 1239-47 (2006) | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
