TargetDisintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q](Human)
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataKi: 0.0600nM ΔG°: -57.8kJ/molepH: 7.3 T: 22°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
3D Structure (crystal)TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
University of Athens
Curated by ChEMBL
University of Athens
Curated by ChEMBL
Affinity DataKi: 0.560nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
University of Athens
Curated by ChEMBL
University of Athens
Curated by ChEMBL
Affinity DataKi: 0.560nMAssay Description:Affinity for Tumor necrosis factor alpha converting enzyme (TACE)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
University of Athens
Curated by ChEMBL
University of Athens
Curated by ChEMBL
Affinity DataKi: 0.560nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 0.560nMAssay Description:Inhibition of TACE in human whole blood assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
University of Athens
Curated by ChEMBL
University of Athens
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Affinity for Tumor necrosis factor alpha converting enzyme (TACE)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of Tumor necrosis factor alpha secretion in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
