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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet  | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | 0.0150 | -61.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Pantarhei Bioscience B.V. US Patent | Assay Description The method employed was adapted from the scientific literature and described in detail by Osboum et al. (1993, Biochemistry, 32, 6229-6236). Recombin... | US Patent US9040509 (2015) BindingDB Entry DOI: 10.7270/Q2Z036WK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | 0.0150 | -61.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
PANTARHEI BIOSCIENCE B.V. US Patent | Assay Description The method employed was adapted from the scientific literature and described in detail by Osbourn et al. (1993, Biochemistry, 32, 6229-6236). Recombi... | US Patent US9034854 (2015) BindingDB Entry DOI: 10.7270/Q2W66JJT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of New Mexico Health Sciences Center Curated by ChEMBL | Assay Description Displacement of E2-Alexa633 from GFP-tagged ERbeta expressed in COS7 cells by FACS | Nat Chem Biol 2: 207-12 (2006) Article DOI: 10.1038/nchembio775 BindingDB Entry DOI: 10.7270/Q2ZK5GV2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Research Curated by ChEMBL | Assay Description Displacement of [3H]estradiol from full length biotinylated human ERbeta by scintillation proximity assay | Bioorg Med Chem Lett 18: 5075-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.121 BindingDB Entry DOI: 10.7270/Q2C53KNF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research and Development Curated by ChEMBL | Assay Description Ability to displace [3H]-17-beta-estradiol from Estrogen receptor beta by scintillation proximity assay. | Bioorg Med Chem Lett 11: 1939-42 (2001) Article DOI: 10.1016/s0960-894x(01)00321-3 BindingDB Entry DOI: 10.7270/Q2ZK5FZ0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Pisa Curated by ChEMBL | Assay Description Relative binding affinity for human estrogen receptor betacompared to [3H]-estradiol | J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]estradiol from full length human recombinant ERbeta after 3 hrs by scintillation proximity assay | Bioorg Med Chem Lett 17: 2322-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.054 BindingDB Entry DOI: 10.7270/Q2PC322G | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of estrogen receptor beta | Bioorg Med Chem Lett 15: 1675-81 (2005) Article DOI: 10.1016/j.bmcl.2005.01.046 BindingDB Entry DOI: 10.7270/Q2S46RFB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of binding to recombinant human estrogen receptor beta | Bioorg Med Chem Lett 15: 107-13 (2004) Article DOI: 10.1016/j.bmcl.2004.10.036 BindingDB Entry DOI: 10.7270/Q2GM86S0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding potency for human ER beta | Bioorg Med Chem Lett 14: 3865-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.073 BindingDB Entry DOI: 10.7270/Q279444V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding potency for human ER beta | Bioorg Med Chem Lett 14: 3861-4 (2004) Article DOI: 10.1016/j.bmcl.2004.05.074 BindingDB Entry DOI: 10.7270/Q2C24VW7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity towards human recombinant Estrogen receptor beta was determined | J Med Chem 47: 2171-5 (2004) Article DOI: 10.1021/jm034243o BindingDB Entry DOI: 10.7270/Q2XK8F08 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity against human estrogen receptor beta (ER beta) in competitive binding assay | Bioorg Med Chem Lett 14: 1417-21 (2004) Article DOI: 10.1016/j.bmcl.2004.01.031 BindingDB Entry DOI: 10.7270/Q28G8K4S | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to human recombinant ERbeta by scintillation proximity assay | Bioorg Med Chem Lett 16: 4652-6 (2006) Article DOI: 10.1016/j.bmcl.2006.05.103 BindingDB Entry DOI: 10.7270/Q2MP52WG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity for human estrogen receptor beta | Bioorg Med Chem Lett 15: 715-8 (2005) Article DOI: 10.1016/j.bmcl.2004.11.018 BindingDB Entry DOI: 10.7270/Q28K78KJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human estrogen receptor 2 using tritiated estradiol incubated for 3 hr | Bioorg Med Chem Lett 15: 3912-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.089 BindingDB Entry DOI: 10.7270/Q2DV1JDB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity for human estrogen receptor beta | Bioorg Med Chem Lett 14: 3753-5 (2004) Article DOI: 10.1016/j.bmcl.2004.04.101 BindingDB Entry DOI: 10.7270/Q29886GZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity for human estrogen receptor beta | Bioorg Med Chem Lett 14: 3747-51 (2004) Article DOI: 10.1016/j.bmcl.2004.04.100 BindingDB Entry DOI: 10.7270/Q2F18Z69 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.18 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cells | Bioorg Med Chem Lett 15: 5562-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.010 BindingDB Entry DOI: 10.7270/Q2N879CK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to ERbeta | Bioorg Med Chem Lett 16: 1468-72 (2006) Article DOI: 10.1016/j.bmcl.2005.12.057 BindingDB Entry DOI: 10.7270/Q2SX6CTN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to human ERbeta | Bioorg Med Chem Lett 16: 834-8 (2006) Article DOI: 10.1016/j.bmcl.2005.11.014 BindingDB Entry DOI: 10.7270/Q2R78G0P | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to human recombinant ERbeta by scintillation proximity assay | Bioorg Med Chem Lett 17: 2944-8 (2007) Article DOI: 10.1016/j.bmcl.2006.12.053 BindingDB Entry DOI: 10.7270/Q2D50NS7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to human ERbeta | Bioorg Med Chem Lett 16: 3896-901 (2006) Article DOI: 10.1016/j.bmcl.2006.05.036 BindingDB Entry DOI: 10.7270/Q24T6J01 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to ERbeta by scintillation proximity assay | Bioorg Med Chem Lett 16: 3489-94 (2006) Article DOI: 10.1016/j.bmcl.2006.03.098 BindingDB Entry DOI: 10.7270/Q2R2110X | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity at human recombinant ERbeta | Bioorg Med Chem Lett 17: 6295-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.001 BindingDB Entry DOI: 10.7270/Q2JQ11VT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | 7.6 | 22 |
Ghent University | Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated polyvinyltoluene scintillation beads (Amersham) and biot... | J Med Chem 49: 7357-65 (2006) Article DOI: 10.1021/jm060692n BindingDB Entry DOI: 10.7270/Q2M61HJ1 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM (Merck Research Laboratories Rome) Curated by ChEMBL | Assay Description Binding affinity to human ER beta | J Med Chem 49: 5404-7 (2006) Article DOI: 10.1021/jm060516e BindingDB Entry DOI: 10.7270/Q2DB81GH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor (255/255 = 100%)† (Rattus norvegicus) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of [3H]17-beta-estradiol binding to rat ER beta expressed in Escherichia coli | J Med Chem 47: 5021-40 (2004) Article DOI: 10.1021/jm049719y BindingDB Entry DOI: 10.7270/Q2C828S5 | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Estrogen receptor (255/255 = 100%)† (Rattus norvegicus) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Research Center Curated by ChEMBL | Assay Description Binding to Estrogen receptor- beta (ER beta) receptor | Bioorg Med Chem Lett 12: 2875-8 (2002) Article DOI: 10.1016/s0960-894x(02)00613-3 BindingDB Entry DOI: 10.7270/Q2F18Z2H | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Corporation Curated by ChEMBL | Assay Description In vitro binding affinity for estrogen receptor beta | Bioorg Med Chem Lett 13: 1919-22 (2003) Article DOI: 10.1016/s0960-894x(03)00307-x BindingDB Entry DOI: 10.7270/Q29K49MK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor (249/255 = 98%)† (Mus musculus) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of [3H]17-beta-estradiol binding to mouse ER beta expressed in Escherichia coli | J Med Chem 47: 5021-40 (2004) Article DOI: 10.1021/jm049719y BindingDB Entry DOI: 10.7270/Q2C828S5 | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens Curated by ChEMBL | Assay Description Displacement of fluorescent estrogen ES2 from human recombinant ERbeta by fluorescence polarization assay | J Nat Prod 72: 1603-7 (2009) Article DOI: 10.1021/np900271m BindingDB Entry DOI: 10.7270/Q2D21XRF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of human LBD of ERbeta | Bioorg Med Chem Lett 17: 118-22 (2006) Article DOI: 10.1016/j.bmcl.2006.09.088 BindingDB Entry DOI: 10.7270/Q2XW4JFX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Binding affinity towards human estrogen receptor beta (ERbeta) | Bioorg Med Chem Lett 13: 2399-403 (2003) Article DOI: 10.1016/s0960-894x(03)00394-9 BindingDB Entry DOI: 10.7270/Q2TB169D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of [3H]-17-beta-estradiol binding to human estrogen receptor beta expressed in Escherichia coli | J Med Chem 48: 3953-79 (2005) Article DOI: 10.1021/jm058173s BindingDB Entry DOI: 10.7270/Q2QF8SF0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of human ERbeta by radioligand binding assay | Bioorg Med Chem Lett 17: 902-6 (2007) Article DOI: 10.1016/j.bmcl.2006.11.066 BindingDB Entry DOI: 10.7270/Q2222TD0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of human estrogen receptor beta | Bioorg Med Chem Lett 15: 3137-42 (2005) Article DOI: 10.1016/j.bmcl.2005.04.013 BindingDB Entry DOI: 10.7270/Q25Q4VMB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Binding affinity for human Estrogen receptor beta | Bioorg Med Chem Lett 14: 4925-9 (2004) Article DOI: 10.1016/j.bmcl.2004.07.029 BindingDB Entry DOI: 10.7270/Q2TM79K8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Binding affinity for human Estrogen receptor beta | Bioorg Med Chem Lett 15: 4520-5 (2005) Article DOI: 10.1016/j.bmcl.2005.07.008 BindingDB Entry DOI: 10.7270/Q20864VH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligand | J Med Chem 47: 5021-40 (2004) Article DOI: 10.1021/jm049719y BindingDB Entry DOI: 10.7270/Q2C828S5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Pharmaceutical University Curated by ChEMBL | Assay Description Binding affinity to human recombinant ERbeta receptor by liquid scintillation counter | Bioorg Med Chem Lett 18: 5050-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.004 BindingDB Entry DOI: 10.7270/Q2KK9BKX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Displacement of [3H]17-beta-estradiol from human Estrogen receptor beta | Bioorg Med Chem Lett 10: 147-51 (2000) Article DOI: 10.1016/s0960-894x(99)00648-4 BindingDB Entry DOI: 10.7270/Q2JH3MQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College Curated by ChEMBL | Assay Description Displacement of fluorescein-labeled estrogen from human recombinant ERbeta by fluorescence polarization based competitive binding affinity assay | J Med Chem 57: 9370-82 (2014) Article DOI: 10.1021/jm500670d BindingDB Entry DOI: 10.7270/Q2BR8TSK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 10.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Charles University in Prague Curated by ChEMBL | Assay Description Antagonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activity after 18 hrs by lu... | J Med Chem 53: 6947-53 (2010) Article DOI: 10.1021/jm100563h BindingDB Entry DOI: 10.7270/Q2PC33M2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 11 | n/a | 0.840 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company | Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor... | J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 16.7 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California Curated by ChEMBL | Assay Description Binding affinity to human ERbeta | J Med Chem 50: 4471-81 (2007) Article DOI: 10.1021/jm070546x BindingDB Entry DOI: 10.7270/Q2XG9RZW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis Pharmaceuticals | Assay Description Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA... | J Med Chem 46: 2945-57 (2003) Article DOI: 10.1021/jm030086h BindingDB Entry DOI: 10.7270/Q2H41PQQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis Pharmaceuticals | Assay Description Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA... | J Med Chem 48: 364-79 (2005) Article DOI: 10.1021/jm040858p BindingDB Entry DOI: 10.7270/Q2CC0XZJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 24 | n/a | 0.0700 | n/a | n/a | 7.4 | 22 |
Novartis Pharmaceuticals | Assay Description Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA... | J Med Chem 45: 1399-401 (2002) Article DOI: 10.1021/jm015577l BindingDB Entry DOI: 10.7270/Q27M0665 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a |
Università di Pisa Curated by ChEMBL | Assay Description Binding affinity for human estrogen receptor beta | J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor (255/255 = 100%)† (Rattus norvegicus) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | n/a | n/a | 0.140 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Effect on ERbeta in rat ovary granulosa cell line transfected with ER responsive luciferase reporter | Bioorg Med Chem Lett 15: 5562-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.010 BindingDB Entry DOI: 10.7270/Q2N879CK | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Agonist activity at human ERbeta in human MCF7 cells assessed as otubain 2 endogenous genes activation after 24 hrs by qPCR | J Med Chem 58: 1184-94 (2015) Article DOI: 10.1021/jm501829f BindingDB Entry DOI: 10.7270/Q2XK8H8P | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.380 | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Agonist activity at human ERbeta expressed in human HEC1 cells assessed as transcriptional activation after 24 hrs by ERE-luciferase reporter gene tr... | J Med Chem 58: 1184-94 (2015) Article DOI: 10.1021/jm501829f BindingDB Entry DOI: 10.7270/Q2XK8H8P | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Research and Development Curated by ChEMBL | Assay Description Agonist effect on transcriptional activation of T47D cells expressing human estrogen receptor beta | J Med Chem 45: 5492-505 (2002) Article DOI: 10.1021/jm020291h BindingDB Entry DOI: 10.7270/Q2J965RW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0850 | n/a | n/a | n/a | n/a |
Phenex Pharmaceuticals AG Curated by ChEMBL | Assay Description Agonist activity at human ERbeta expressed in HEK293 cells by luciferase reporter gene assay | Bioorg Med Chem Lett 24: 5265-7 (2014) Article DOI: 10.1016/j.bmcl.2014.09.053 BindingDB Entry DOI: 10.7270/Q2S46TKZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 9.70 | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Curated by ChEMBL | Assay Description In vitro agonist activity for estrogen receptor beta expressed in COS-1 cells | Bioorg Med Chem Lett 15: 1463-6 (2005) Article DOI: 10.1016/j.bmcl.2004.12.077 BindingDB Entry DOI: 10.7270/Q25H7FR7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Urbana-Champaign Curated by ChEMBL | Assay Description Binding affinity to full-length human estrogen receptor beta | Bioorg Med Chem 17: 3528-35 (2009) Article DOI: 10.1016/j.bmc.2009.04.016 BindingDB Entry DOI: 10.7270/Q22R3RP1 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a |
University of Illinois Curated by ChEMBL | Assay Description Agonist activity at ERbeta expressed in human HEC1 cells assessed as transcriptional potency after 24 hrs by luciferase-beta galactosidase reporter g... | Eur J Med Chem 44: 3412-24 (2009) Article DOI: 10.1016/j.ejmech.2009.02.006 BindingDB Entry DOI: 10.7270/Q2NK3F37 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a |
University of Illinois Curated by ChEMBL | Assay Description Binding affinity to human full length ERbeta receptor | Eur J Med Chem 44: 3412-24 (2009) Article DOI: 10.1016/j.ejmech.2009.02.006 BindingDB Entry DOI: 10.7270/Q2NK3F37 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 280 | n/a | n/a | n/a | n/a |
Technische Universiteit Eindhoven Curated by ChEMBL | Assay Description Agonist activity at human N-terminal His6-tagged ERbeta receptor LBD expressed in Escherichia coli BL21 (DE3) assessed as induction of SRC1 peptide r... | J Med Chem 54: 2005-11 (2011) Article DOI: 10.1021/jm1011116 BindingDB Entry DOI: 10.7270/Q2R49R3P | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.720 | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Agonist activity at human full-length ERbeta receptor expressed in human HEC1 cells co-expressing (ERE)2-pS2-luc gene assessed as transcriptional act... | Eur J Med Chem 46: 2453-62 (2011) Article DOI: 10.1016/j.ejmech.2011.03.030 BindingDB Entry DOI: 10.7270/Q2ZC8362 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Binding affinity to human full-length ERbeta receptor | Eur J Med Chem 46: 2453-62 (2011) Article DOI: 10.1016/j.ejmech.2011.03.030 BindingDB Entry DOI: 10.7270/Q2ZC8362 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.25 | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Agonist activity at ERbeta expressed in UAS cells co-expressing beta-lactamase after 18 hrs by beta-lactamase reporter gene assay | Bioorg Med Chem Lett 21: 5680-3 (2011) Article DOI: 10.1016/j.bmcl.2011.08.041 BindingDB Entry DOI: 10.7270/Q2JS9QTC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a |
University of Illinois Curated by ChEMBL | Assay Description Agonist activity at human ERbeta expressed in U2OS cells coexpressing pCMX-hSRC3 assessed as luciferase activity after 24 hrs by reporter gene assay | J Med Chem 55: 528-37 (2012) Article DOI: 10.1021/jm201436k BindingDB Entry DOI: 10.7270/Q2PN963M | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a |
University of Illinois Curated by ChEMBL | Assay Description Agonist activity at human ERbeta expressed in HEC-1 cells coexpressing beta-gal assessed as luciferase activity after 24 hrs by reporter gene assay | J Med Chem 55: 528-37 (2012) Article DOI: 10.1021/jm201436k BindingDB Entry DOI: 10.7270/Q2PN963M | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a |
University of Illinois Curated by ChEMBL | Assay Description Agonist activity at human N-His6-tagged terbium-labelled ERbeta ligand binding domain expressed in Escherichia coli BL21 cells assessed as recruitmen... | J Med Chem 55: 528-37 (2012) Article DOI: 10.1021/jm201436k BindingDB Entry DOI: 10.7270/Q2PN963M | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a |
University of Illinois Curated by ChEMBL | Assay Description Agonist activity at human N-His6-tagged terbium-labelled NRID-SRC3 of ERbeta ligand binding domain expressed in Escherichia coli BL21 cells after 1 h... | J Med Chem 55: 528-37 (2012) Article DOI: 10.1021/jm201436k BindingDB Entry DOI: 10.7270/Q2PN963M | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
Wuhan University Curated by ChEMBL | Assay Description Agonist activity at human ERbeta expressed in HepG2 cells after 24 hrs by luciferase reporter gene assay | J Med Chem 55: 2324-41 (2012) Article DOI: 10.1021/jm201556r BindingDB Entry DOI: 10.7270/Q2VT1T4R | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.670 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Ability to activate estrogen receptor 2-mediated transcription. | Bioorg Med Chem Lett 14: 2327-30 (2004) Article DOI: 10.1016/j.bmcl.2004.01.099 BindingDB Entry DOI: 10.7270/Q2HT2PVS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effect on transactivation of ALP gene expression in HEK293 cells transfected with hERbeta | Bioorg Med Chem Lett 16: 834-8 (2006) Article DOI: 10.1016/j.bmcl.2005.11.014 BindingDB Entry DOI: 10.7270/Q2R78G0P | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Agonist activity at human recombinant ERbeta expressed in HEK293 cells by transactivation assay | Bioorg Med Chem Lett 17: 2944-8 (2007) Article DOI: 10.1016/j.bmcl.2006.12.053 BindingDB Entry DOI: 10.7270/Q2D50NS7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Agonist activity at ERbeta expressed in HEK293 cells by transactivation assay | Bioorg Med Chem Lett 17: 6295-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.001 BindingDB Entry DOI: 10.7270/Q2JQ11VT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University) Curated by ChEMBL | Assay Description Binding affinity to human full length estrogen receptor beta by Scatchard plot analysis | J Med Chem 56: 3346-66 (2013) Article DOI: 10.1021/jm400157e BindingDB Entry DOI: 10.7270/Q2MK6F7V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Agonist activity at estrogen receptor beta ligand binding domain expressed in african green monkey COS7 cells co-transfected with Gal4-LBD by lucifer... | J Nat Prod 72: 1944-8 (2009) Article DOI: 10.1021/np9004882 BindingDB Entry DOI: 10.7270/Q2R49RQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0100 | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin Curated by ChEMBL | Assay Description Activation of human ERbeta expressed in human U2-OS cells by luciferase reporter gene assay relative to untreated control | J Med Chem 55: 9607-18 (2012) Article DOI: 10.1021/jm300860j BindingDB Entry DOI: 10.7270/Q2R212H2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.458 | n/a | n/a | n/a | n/a |
Charles University in Prague Curated by ChEMBL | Assay Description Agonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucifer... | J Med Chem 53: 6947-53 (2010) Article DOI: 10.1021/jm100563h BindingDB Entry DOI: 10.7270/Q2PC33M2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.08 | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Agonist activity at ERbeta expressed in yeast assessed as alpha-galactosidase activity | J Med Chem 53: 5361-5 (2010) Article DOI: 10.1021/jm100369g BindingDB Entry DOI: 10.7270/Q2319WV8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Agonist activity at ERbeta expressed in CHO-K1 cells by luciferase reporter gene transactivation assay | J Med Chem 53: 5361-5 (2010) Article DOI: 10.1021/jm100369g BindingDB Entry DOI: 10.7270/Q2319WV8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Agonist activity at human ERbeta LBD by cell based luciferase reporter gene assay | J Med Chem 54: 788-808 (2012) Article DOI: 10.1021/jm101063h BindingDB Entry DOI: 10.7270/Q208668Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0360 | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Transcriptional activation of ERbeta receptor expressed in CHO-K1 cells after 24 hrs by luciferase reporter gene assay | Eur J Med Chem 54: 188-96 (2012) Article DOI: 10.1016/j.ejmech.2012.04.041 BindingDB Entry DOI: 10.7270/Q2445NJ5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.08 | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Agonist activity at ERbeta receptor LBD expressed in yeast AH109 cells assessed as interaction with SRC1 after 24 hrs by alpha-galactosidase assay | Eur J Med Chem 54: 188-96 (2012) Article DOI: 10.1016/j.ejmech.2012.04.041 BindingDB Entry DOI: 10.7270/Q2445NJ5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0390 | n/a | n/a | n/a | n/a |
University of Illinois Curated by ChEMBL | Assay Description Transcriptional potency (EC50) at Human estrogen receptor Beta | J Med Chem 44: 4230-51 (2001) Article DOI: 10.1021/jm010254a BindingDB Entry DOI: 10.7270/Q289155W | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0980 | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Transcriptional activation of estrogen receptor beta in U2OS cell using estrogen-regulated luciferase reporter gene plasmid upon incubation for 20-30... | J Med Chem 48: 5989-6003 (2005) Article DOI: 10.1021/jm050226i BindingDB Entry DOI: 10.7270/Q2B857P7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.130 | n/a | n/a | n/a | n/a |
Universita di Pisa Curated by ChEMBL | Assay Description Agonist activity at full-length human estrogen receptor beta expressed in human HEC1 cells assessed as transcriptional activation after 24 hrs by luc... | J Med Chem 52: 858-67 (2009) Article DOI: 10.1021/jm801458t BindingDB Entry DOI: 10.7270/Q23R0SRH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a |
Institute of Radiological and Medical Sciences Curated by ChEMBL | Assay Description Binding affinity to full-length human estrogen receptor beta | Bioorg Med Chem 17: 3479-88 (2009) Article DOI: 10.1016/j.bmc.2009.02.064 BindingDB Entry DOI: 10.7270/Q2T43T0H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a |
Università di Pisa Curated by ChEMBL | Assay Description Displacement of [3H]estradiol from human ERbeta | J Med Chem 49: 5001-12 (2006) Article DOI: 10.1021/jm060560u BindingDB Entry DOI: 10.7270/Q2ZG6RVQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
