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Report error Found 5 Enz. Inhib. hit(s) for PDB: 2JT6
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096645(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Affinity DataIC50:  25nMAssay Description:Inhibition of Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096645(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Affinity DataIC50:  47nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096645(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Affinity DataIC50:  57nMAssay Description:In vitro inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096645(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Affinity DataKd:  110nMAssay Description:Binding affinity to stromelysin-1 catalytic domain expressed in Escherichia coli BL21 (DE3) by isothermal titration colorimetryMore data for this Ligand-Target Pair
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096645(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Affinity DataKd:  100nMAssay Description:Binding affinity to stromelysin-1 catalytic domainMore data for this Ligand-Target Pair