Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Intestinal fatty acid-binding protein (hIFABP) (131/131 = 100%)† (Homo sapiens (Human)) | BDBM85511![]() (CAS_74103-07-4 | KETOROLAC | Ketorolac tris salt |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 9.40E+3 | -54.5 | n/a | n/a | n/a | n/a | n/a | n/a | 293.15 |
Monash University | Assay Description Briefly, steady-state fluorescence spectra of ANS binding was monitored by measuring the increase in fluorescence signal between 450?550 nm following... | ACS Chem Biol 9: 2526-34 (2014) Article DOI: 10.1021/cb5005178 BindingDB Entry DOI: 10.7270/Q2348J4C | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Intestinal fatty acid-binding protein (hIFABP) (131/131 = 100%)† (Homo sapiens (Human)) | BDBM85511![]() (CAS_74103-07-4 | KETOROLAC | Ketorolac tris salt |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 5.67E+4 | n/a | n/a | n/a | 8.0 | 37 |
Monash University | Assay Description ITC experiments were carried out using an iTC200 microcalorimeter (MicroCal) with coin shaped sample cell (200 μL) at 37 C with stirring at 1000... | ACS Chem Biol 9: 2526-34 (2014) Article DOI: 10.1021/cb5005178 BindingDB Entry DOI: 10.7270/Q2348J4C | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |
Cell (A) | Syringe (B) | Cell Links | Syringe Links | Cell + Syr Links | ΔG° kJ/mole | -TΔS° kJ/mole | ΔH° kJ/mole | log K | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|
Intestinal fatty acid-binding protein (hIFABP) (131/131 = 100%)† (Homo sapiens (Human)) | BDBM85511![]() (CAS_74103-07-4 | KETOROLAC | Ketorolac tris salt |...) | GoogleScholar PDB | DrugBank KEGG PC cid PC sid PDB | -25.2 | -25.5 | 0.300 | 4.24 | 8 | 37 | |
Monash University | ACS Chem Biol 9: 2526-34 (2014) |
Cell (A) | Syringe (B) | Cell Links | Syringe Links | Cell + Syr Links | ΔG° kJ/mole | -TΔS° kJ/mole | ΔH° kJ/mole | log K | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|
Intestinal fatty acid-binding protein (hIFABP) (131/131 = 100%)† (Homo sapiens (Human)) | BDBM85511![]() (CAS_74103-07-4 | KETOROLAC | Ketorolac tris salt |...) | GoogleScholar PDB | DrugBank KEGG PC cid PC sid PDB | -25.2 | -25.5 | 0.300 | 4.24 | 8 | 37 | |
Monash University | ACS Chem Biol 9: 2526-34 (2014) |