Affinity Data by PDB ID

PDB code 2OAH

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-secretase 1 (402/404 > 99%)^† (Homo sapiens (Human))	BDBM16680 (Mixture of trans methyl(cyclopropylmethyl)diastere...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	37
Merck Research Laboratories					Assay Description HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...				Bioorg Med Chem Lett 17: 1788-92 (2007) Article DOI: 10.1016/j.bmcl.2006.12.051 BindingDB Entry DOI: 10.7270/Q2CF9NCQ
Merck Research Laboratories					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output