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Found 1 Enz. Inhib. hit(s) for PDB: 2OJG
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM15614(N,N-dimethyl-4-(4-phenyl-1H-pyrazol-3-yl)-1H-pyrro...)
Affinity DataKi:  2.30E+3nM ΔG°:  -32.7kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by ERK2 was converted to ATP by pyruvate kinase with the production of pyruvate fr...More data for this Ligand-Target Pair