Affinity Data by PDB ID

PDB code 2PVV

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate Carboxypeptidase II (GCPII) (707/707 = 100%)^† (Homo sapiens (Human))	BDBM17663 ((2S)-2-amino-3-(sulfooxy)propanoic acid \| L-SOS \| ...) Show SMILES N[C@@H](COS(O)(=O)=O)C(O)=O Show InChI	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar	Purchase CHEBI KEGG MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	n/a	n/a	4.38E+5	n/a	n/a	n/a	n/a	7.4	37
NCI-FCRDC					Assay Description The inhibition concentration values of GCPII were determined using the radioenzymatic assay with [3H] NAAG (radiolabeled on the terminal glutamate). ...				J Med Chem 50: 3267-73 (2007) Article DOI: 10.1021/jm070133w BindingDB Entry DOI: 10.7270/Q29C6VPS
NCI-FCRDC					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output