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Report error Found 3 Enz. Inhib. hit(s) for PDB: 2Z65
TargetToll-like receptor 4(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50274760(3-O-DECYL-2-DEOXY-6-O-{2-DEOXY-3-O-[(3R)-3-METHOXY...)
Affinity DataIC50:  1.5nMAssay Description:Antagonist activity at human TLR4 expressed in HE293 cells by ELAM1-luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetToll-like receptor 4(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50274760(3-O-DECYL-2-DEOXY-6-O-{2-DEOXY-3-O-[(3R)-3-METHOXY...)
Affinity DataIC50:  1.5nMAssay Description:Antagonist activity at TLR4 in human serum assessed as reduction in LPS-induced TNFalpha production after 3 hrs by ELISAMore data for this Ligand-Target Pair
TargetToll-like receptor 4(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50274760(3-O-DECYL-2-DEOXY-6-O-{2-DEOXY-3-O-[(3R)-3-METHOXY...)
Affinity DataIC50:  1.5nMAssay Description:Antagonist activity at TLR4 in human HL60 cells assessed as inhibition of LPS-induced cytokine productionMore data for this Ligand-Target Pair