TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
TargetDisintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q](Homo sapiens (Human))
Vertex Pharmaceuticals
Vertex Pharmaceuticals
Affinity DataKi: 10nM ΔG°: -45.2kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for TACE inhibition using fluorescence resonance energy transfer (FRET) assay. TACE catalyzed cleavage of the substrate pep...More data for this Ligand-Target Pair